CSH2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CSH2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CSH2 at tissue level.

III. Associated gene sets

GO_0042531Biological processpositive regulation of tyrosine phosphorylation of STAT protein
GO_0060396Biological processgrowth hormone receptor signaling pathway
GO_0031667Biological processresponse to nutrient levels
GO_0045927Biological processpositive regulation of growth
GO_0046427Biological processpositive regulation of receptor signaling pathway via JAK-STAT
GO_0048513Biological processanimal organ development
GO_0005615Cellular componentextracellular space
GO_0005783Cellular componentendoplasmic reticulum
GO_0031982Cellular componentvesicle
GO_0005131Molecular functiongrowth hormone receptor binding
GO_0008083Molecular functiongrowth factor activity
GO_0005179Molecular functionhormone activity
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameCSH2
Protein nameChorionic somatomammotropin hormone 2
Chorionic somatomammotropin hormone 2 isoform 2
Chorionic somatomammotropin hormone 2 isoform 3
Chorionic somatomammotropin hormone 2 (Choriomammotropin) (Lactogen) (Placental lactogen) (PL)
Synonyms
DescriptionFUNCTION: Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. .

AccessionsENST00000392886.7 [P0DML3-1]
ENST00000560142.5
ENST00000345366.8 [P0DML3-3]
H0YM39
B1A4H9
P0DML3
A6NIT4
ENST00000336844.9 [P0DML3-2]