UGGT1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0018279Biological processprotein N-linked glycosylation via asparagine
GO_0097359Biological processUDP-glucosylation
GO_0051084Biological process'de novo' post-translational protein folding
GO_0036503Biological processERAD pathway
GO_0005788Cellular componentendoplasmic reticulum lumen
GO_0070062Cellular componentextracellular exosome
GO_0032991Cellular componentprotein-containing complex
GO_0005783Cellular componentendoplasmic reticulum
GO_0005793Cellular componentendoplasmic reticulum-Golgi intermediate compartment
GO_0003980Molecular functionUDP-glucose:glycoprotein glucosyltransferase activity
GO_0005515Molecular functionprotein binding
GO_0051082Molecular functionunfolded protein binding

IV. Literature review

[source]
Gene nameUGGT1
Protein nameUDP-glucose glycoprotein glucosyltransferase 1
Alternative protein UGGT1
UDP-glucose:glycoprotein glucosyltransferase 1 (UGT1) (hUGT1) (EC 2.4.1.-) (UDP--Glc:glycoprotein glucosyltransferase) (UDP-glucose ceramide glucosyltransferase-like 1)
SynonymsUGCGL1
UGGT
UGTR
GT
UGT1
DescriptionFUNCTION: Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation. .

AccessionsENST00000376723.7
F8WCI2
H7BZG0
L8ECI4
Q9NYU2
ENST00000430075.5
ENST00000438277.5
ENST00000418197.1
ENST00000259253.11 [Q9NYU2-1]
E2QRN8
F8WCE6