CSH1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CSH1 at tissue level.

III. Associated gene sets

GO_0042531Biological processpositive regulation of tyrosine phosphorylation of STAT protein
GO_0060396Biological processgrowth hormone receptor signaling pathway
GO_0031667Biological processresponse to nutrient levels
GO_0045927Biological processpositive regulation of growth
GO_0046427Biological processpositive regulation of receptor signaling pathway via JAK-STAT
GO_0048513Biological processanimal organ development
GO_0005615Cellular componentextracellular space
GO_0005783Cellular componentendoplasmic reticulum
GO_0005576Cellular componentextracellular region
GO_0031982Cellular componentvesicle
GO_0031904Cellular componentendosome lumen
GO_0005131Molecular functiongrowth hormone receptor binding
GO_0008083Molecular functiongrowth factor activity
GO_0005179Molecular functionhormone activity
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameCSH1
Protein nameChorionic somatomammotropin hormone 1 (Choriomammotropin) (Lactogen) (Placental lactogen) (PL)
Chorionic somatomammotropin hormone 1 (Placental lactogen)
Chorionic somatomammotropin hormone 1 (Chorionic somatomammotropin hormone 2)
Chorionic somatomammotropin hormone 1 isoform 1 (Growth hormone B3) (HCG1749481, isoform CRA_c) (HCG1749481, isoform CRA_e) (HCG1749481, isoform CRA_i) (cDNA FLJ75407, highly similar to Homo sapiens chorionic somatomammotropin hormone 1 (placental lactogen) (CSH1), transcript variant 1, mRNA)
Chorionic somatomammotropin hormone 1 (HCG1749481, isoform CRA_k)
Chorionic somatomammotropin hormone 1 (HCG1749481, isoform CRA_d) (HCG1749481, isoform CRA_w) (HCG1749481, isoform CRA_y)
SynonymsCSH2
GHB3
hCG_1749481
DescriptionFUNCTION: Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. .

AccessionsENST00000453363.7
P0DML2
ENST00000316193.13
A8K6C2
A0A087WUG6
A6NFB4
ENST00000329882.8
ENST00000613718.3
B1A4H2
ENST00000610991.1
Q6PF11