Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| extravillous trophoblast | 3 studies | 51% ± 25% |
Insufficient scRNA-seq data for expression of CSH1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 0% | 0 | 0 / 1445 | 1% | 0.58 | 1 / 183 |
| adrenal gland | 0% | 0.52 | 1 / 258 | 0% | 0 | 0 / 230 |
| intestine | 0% | 0 | 0 / 966 | 0% | 0.45 | 2 / 527 |
| lung | 0% | 0 | 0 / 578 | 0% | 0.01 | 3 / 1155 |
| uterus | 0% | 0 | 0 / 170 | 0% | 0.02 | 1 / 459 |
| bladder | 0% | 0 | 0 / 21 | 0% | 0.00 | 1 / 504 |
| thymus | 0% | 0 | 0 / 653 | 0% | 0.00 | 1 / 605 |
| skin | 0% | 0.17 | 2 / 1809 | 0% | 0 | 0 / 472 |
| adipose | 0% | 2.07 | 1 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0.08 | 1 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| brain | 0% | 0 | 0 / 2642 | 0% | 0 | 0 / 705 |
| breast | 0% | 0 | 0 / 459 | 0% | 0 | 0 / 1118 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| kidney | 0% | 0 | 0 / 89 | 0% | 0 | 0 / 901 |
| liver | 0% | 0 | 0 / 226 | 0% | 0 | 0 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ovary | 0% | 0 | 0 / 180 | 0% | 0 | 0 / 430 |
| pancreas | 0% | 0 | 0 / 328 | 0% | 0 | 0 / 178 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| prostate | 0% | 0 | 0 / 245 | 0% | 0 | 0 / 502 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| stomach | 0% | 0 | 0 / 359 | 0% | 0 | 0 / 286 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0042531 | Biological process | positive regulation of tyrosine phosphorylation of STAT protein |
| GO_0060396 | Biological process | growth hormone receptor signaling pathway |
| GO_0031667 | Biological process | response to nutrient levels |
| GO_0045927 | Biological process | positive regulation of growth |
| GO_0046427 | Biological process | positive regulation of receptor signaling pathway via JAK-STAT |
| GO_0048513 | Biological process | animal organ development |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005576 | Cellular component | extracellular region |
| GO_0031982 | Cellular component | vesicle |
| GO_0031904 | Cellular component | endosome lumen |
| GO_0005131 | Molecular function | growth hormone receptor binding |
| GO_0008083 | Molecular function | growth factor activity |
| GO_0005179 | Molecular function | hormone activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | CSH1 |
| Protein name | Chorionic somatomammotropin hormone 1 (Choriomammotropin) (Lactogen) (Placental lactogen) (PL) Chorionic somatomammotropin hormone 1 (Placental lactogen) Chorionic somatomammotropin hormone 1 (Chorionic somatomammotropin hormone 2) Chorionic somatomammotropin hormone 1 isoform 1 (Growth hormone B3) (HCG1749481, isoform CRA_c) (HCG1749481, isoform CRA_e) (HCG1749481, isoform CRA_i) (cDNA FLJ75407, highly similar to Homo sapiens chorionic somatomammotropin hormone 1 (placental lactogen) (CSH1), transcript variant 1, mRNA) Chorionic somatomammotropin hormone 1 (HCG1749481, isoform CRA_k) Chorionic somatomammotropin hormone 1 (HCG1749481, isoform CRA_d) (HCG1749481, isoform CRA_w) (HCG1749481, isoform CRA_y) |
| Synonyms | CSH2 GHB3 hCG_1749481 |
| Description | FUNCTION: Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. . |
| Accessions | ENST00000453363.7 P0DML2 ENST00000316193.13 A8K6C2 A0A087WUG6 A6NFB4 ENST00000329882.8 ENST00000613718.3 B1A4H2 ENST00000610991.1 Q6PF11 |