FATE1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of FATE1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of FATE1 at tissue level.

III. Associated gene sets

GO_0006915Biological processapoptotic process
GO_0043066Biological processnegative regulation of apoptotic process
GO_0051562Biological processnegative regulation of mitochondrial calcium ion concentration
GO_0005741Cellular componentmitochondrial outer membrane
GO_0044233Cellular componentmitochondria-associated endoplasmic reticulum membrane contact site
GO_0005783Cellular componentendoplasmic reticulum
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0042802Molecular functionidentical protein binding
GO_0031625Molecular functionubiquitin protein ligase binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameFATE1
Protein nameFetal and adult testis-expressed transcript protein (Cancer/testis antigen 43) (CT43) (Tumor antigen BJ-HCC-2)
Fetal and adult testis expressed 1
SynonymsFATE
DescriptionFUNCTION: Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER-mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis . May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling . .

AccessionsH7C1I5
Q969F0
ENST00000370350.7
ENST00000417321.1