ERGIC3 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	32 studies	35% ± 16%	Explore
CD4-positive, alpha-beta T cell	25 studies	26% ± 8%	Explore
plasma cell	24 studies	46% ± 22%	Explore
natural killer cell	23 studies	25% ± 7%	Explore
B cell	23 studies	27% ± 10%	Explore
endothelial cell	23 studies	29% ± 15%	Explore
conventional dendritic cell	22 studies	35% ± 16%	Explore
CD8-positive, alpha-beta T cell	21 studies	27% ± 8%	Explore
epithelial cell	20 studies	43% ± 22%	Explore
macrophage	20 studies	32% ± 14%	Explore
classical monocyte	20 studies	30% ± 9%	Explore
ciliated cell	19 studies	62% ± 21%	Explore
non-classical monocyte	18 studies	31% ± 11%	Explore
T cell	18 studies	27% ± 13%	Explore
basal cell	18 studies	40% ± 21%	Explore
pericyte	18 studies	32% ± 15%	Explore
regulatory T cell	18 studies	29% ± 7%	Explore
plasmacytoid dendritic cell	17 studies	41% ± 13%	Explore
smooth muscle cell	17 studies	30% ± 14%	Explore
memory B cell	16 studies	24% ± 6%	Explore
connective tissue cell	16 studies	43% ± 19%	Explore
monocyte	15 studies	30% ± 12%	Explore
gamma-delta T cell	13 studies	28% ± 11%	Explore
naive B cell	13 studies	23% ± 5%	Explore
secretory cell	12 studies	37% ± 18%	Explore
myofibroblast cell	12 studies	40% ± 17%	Explore
endothelial cell of lymphatic vessel	12 studies	31% ± 12%	Explore
plasmablast	11 studies	46% ± 23%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	27% ± 11%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	26% ± 6%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	24% ± 6%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	10 studies	26% ± 5%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	29% ± 5%	Explore
abnormal cell	10 studies	36% ± 15%	Explore
goblet cell	9 studies	35% ± 13%	Explore
mesothelial cell	9 studies	49% ± 24%	Explore
dendritic cell	9 studies	43% ± 20%	Explore
mucosal invariant T cell	9 studies	25% ± 4%	Explore
mast cell	9 studies	22% ± 7%	Explore
type I pneumocyte	8 studies	27% ± 15%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	30% ± 8%	Explore
mature NK T cell	8 studies	22% ± 5%	Explore
progenitor cell	8 studies	47% ± 17%	Explore
endothelial cell of artery	8 studies	24% ± 8%	Explore
vein endothelial cell	8 studies	29% ± 14%	Explore
IgG plasma cell	8 studies	35% ± 14%	Explore
T follicular helper cell	8 studies	27% ± 9%	Explore
club cell	7 studies	44% ± 10%	Explore
endothelial cell of vascular tree	7 studies	26% ± 5%	Explore
myeloid cell	7 studies	28% ± 11%	Explore
hematopoietic precursor cell	6 studies	39% ± 17%	Explore
respiratory goblet cell	6 studies	37% ± 21%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	26% ± 6%	Explore
capillary endothelial cell	6 studies	26% ± 14%	Explore
epithelial cell of proximal tubule	6 studies	32% ± 18%	Explore
IgA plasma cell	6 studies	40% ± 14%	Explore
hematopoietic stem cell	6 studies	44% ± 16%	Explore
innate lymphoid cell	6 studies	25% ± 6%	Explore
type II pneumocyte	6 studies	40% ± 18%	Explore
ionocyte	5 studies	26% ± 11%	Explore
kidney loop of Henle epithelial cell	5 studies	27% ± 13%	Explore
enterocyte	5 studies	31% ± 8%	Explore
enteroendocrine cell	5 studies	42% ± 17%	Explore
transit amplifying cell	5 studies	30% ± 11%	Explore
erythroblast	5 studies	30% ± 15%	Explore
precursor B cell	5 studies	33% ± 8%	Explore
neuron	5 studies	43% ± 20%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	31% ± 6%	Explore
deuterosomal cell	4 studies	44% ± 11%	Explore
pancreatic A cell	4 studies	35% ± 11%	Explore
mononuclear phagocyte	4 studies	34% ± 17%	Explore
exhausted T cell	4 studies	33% ± 6%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	55% ± 20%	Explore
intestinal crypt stem cell	4 studies	41% ± 15%	Explore
leukocyte	4 studies	27% ± 8%	Explore
pro-B cell	4 studies	31% ± 8%	Explore
immature B cell	4 studies	39% ± 14%	Explore
astrocyte	4 studies	25% ± 14%	Explore
adventitial cell	4 studies	26% ± 10%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	42% ± 8%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	45% ± 16%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	33% ± 7%	Explore
oligodendrocyte precursor cell	4 studies	32% ± 15%	Explore
brush cell	4 studies	19% ± 3%	Explore
erythrocyte	4 studies	36% ± 19%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	24% ± 5%	Explore
duct epithelial cell	3 studies	38% ± 13%	Explore
precursor cell	3 studies	55% ± 13%	Explore
squamous epithelial cell	3 studies	37% ± 25%	Explore
type B pancreatic cell	3 studies	33% ± 6%	Explore
renal alpha-intercalated cell	3 studies	40% ± 17%	Explore
neural crest cell	3 studies	43% ± 13%	Explore
extravillous trophoblast	3 studies	68% ± 14%	Explore
placental villous trophoblast	3 studies	74% ± 22%	Explore
common myeloid progenitor	3 studies	46% ± 23%	Explore
lymphocyte	3 studies	26% ± 7%	Explore
alveolar macrophage	3 studies	22% ± 3%	Explore
mucus secreting cell	3 studies	38% ± 12%	Explore
serous secreting cell	3 studies	49% ± 11%	Explore
muscle cell	3 studies	29% ± 15%	Explore
intermediate monocyte	3 studies	42% ± 17%	Explore
luminal cell of prostate epithelium	3 studies	31% ± 11%	Explore
IgM plasma cell	3 studies	34% ± 10%	Explore
glutamatergic neuron	3 studies	29% ± 10%	Explore
granulocyte	3 studies	28% ± 8%	Explore
granulocyte monocyte progenitor cell	3 studies	39% ± 16%	Explore
group 3 innate lymphoid cell	3 studies	33% ± 9%	Explore
T-helper 1 cell	3 studies	28% ± 7%	Explore
T-helper 17 cell	3 studies	23% ± 5%	Explore
double negative thymocyte	3 studies	39% ± 15%	Explore
progenitor cell of mammary luminal epithelium	3 studies	45% ± 20%	Explore
hepatocyte	3 studies	40% ± 28%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	15 studies	38% ± 17%	Explore
peripheral blood	13 studies	30% ± 6%	Explore
intestine	10 studies	32% ± 15%	Explore
kidney	8 studies	28% ± 10%	Explore
bone marrow	6 studies	20% ± 4%	Explore
brain	6 studies	21% ± 6%	Explore
placenta	5 studies	41% ± 27%	Explore
lymph node	5 studies	29% ± 12%	Explore
pancreas	4 studies	34% ± 11%	Explore
uterus	4 studies	34% ± 19%	Explore
breast	4 studies	30% ± 13%	Explore
liver	4 studies	30% ± 16%	Explore
skin	3 studies	29% ± 3%	Explore
adrenal gland	3 studies	22% ± 6%	Explore
prostate	3 studies	26% ± 8%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	6819.55	1445 / 1445	100%	118.28	183 / 183
liver	100%	5230.81	226 / 226	100%	100.05	406 / 406
ovary	100%	10502.33	180 / 180	100%	208.88	430 / 430
pancreas	100%	6548.20	328 / 328	100%	129.72	178 / 178
skin	100%	10428.54	1809 / 1809	100%	172.54	472 / 472
stomach	100%	7643.33	359 / 359	100%	188.13	286 / 286
thymus	100%	11002.86	653 / 653	100%	154.96	604 / 605
lung	100%	7834.42	578 / 578	100%	148.89	1153 / 1155
breast	100%	8940.86	459 / 459	100%	156.18	1116 / 1118
prostate	100%	8818.52	245 / 245	100%	151.36	501 / 502
intestine	100%	8116.98	966 / 966	100%	198.16	525 / 527
uterus	100%	9141.04	170 / 170	100%	156.19	457 / 459
brain	100%	4271.94	2629 / 2642	100%	115.74	705 / 705
kidney	100%	8263.81	89 / 89	99%	105.91	895 / 901
bladder	100%	7958.86	21 / 21	99%	191.40	500 / 504
adrenal gland	100%	10014.17	258 / 258	99%	90.71	228 / 230
adipose	100%	7758.19	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	153.38	80 / 80
lymph node	0%	0	0 / 0	100%	104.39	29 / 29
spleen	100%	7332.80	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	125.06	45 / 45
ureter	0%	0	0 / 0	100%	83.47	1 / 1
blood vessel	100%	7389.87	1334 / 1335	0%	0	0 / 0
muscle	99%	3696.58	794 / 803	0%	0	0 / 0
peripheral blood	98%	4852.16	913 / 929	0%	0	0 / 0
heart	98%	4696.58	845 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006888	Biological process	endoplasmic reticulum to Golgi vesicle-mediated transport
GO_0006890	Biological process	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
GO_0090316	Biological process	positive regulation of intracellular protein transport
GO_0033116	Cellular component	endoplasmic reticulum-Golgi intermediate compartment membrane
GO_0000139	Cellular component	Golgi membrane
GO_0005783	Cellular component	endoplasmic reticulum
GO_0061852	Cellular component	retrograde transporter complex, Golgi to ER
GO_1990351	Cellular component	transporter complex
GO_0030134	Cellular component	COPII-coated ER to Golgi transport vesicle
GO_0016020	Cellular component	membrane
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	ERGIC3
Protein name	Endoplasmic reticulum-Golgi intermediate compartment protein 3 (Serologically defined breast cancer antigen NY-BR-84) Endoplasmic reticulum-Golgi intermediate compartment protein
Synonyms	RP3-477O4.12-011 PRO0989 hCG_38214 SDBCAG84 RP3-477O4.12-008 CGI-54 C20orf47 RP3-477O4.12-015 RP3-477O4.12-006 ERV46 RP3-477O4.12-017
Description	FUNCTION: Possible role in transport between endoplasmic reticulum and Golgi. Positively regulates trafficking of the secretory proteins SERPINA1/alpha1-antitrypsin and HP/haptoglobin . . FUNCTION: Plays a role in transport between endoplasmic reticulum and Golgi. . FUNCTION: Plays a role in transport between endoplasmic reticulum and Golgi. . FUNCTION: Plays a role in transport between endoplasmic reticulum and Golgi. . FUNCTION: Plays a role in transport between endoplasmic reticulum and Golgi. . FUNCTION: Plays a role in transport between endoplasmic reticulum and Golgi. . FUNCTION: Plays a role in transport between endoplasmic reticulum and Golgi. . FUNCTION: Plays a role in transport between endoplasmic reticulum and Golgi. . FUNCTION: Plays a role in transport between endoplasmic reticulum and Golgi. . FUNCTION: Plays a role in transport between endoplasmic reticulum and Golgi. . FUNCTION: Plays a role in transport between endoplasmic reticulum and Golgi. . FUNCTION: Plays a role in transport between endoplasmic reticulum and Golgi. .
Accessions	Q5JWS1 Q5JWS0 H0Y621 ENST00000451605.1 Q5JWS2 Q9Y282 ENST00000348547.7 [Q9Y282-1] A2TJK5 H0Y5K5 A0A0C4DH46 ENST00000442139.5 A6PVJ3 H0Y802 ENST00000411577.5 ENST00000413587.5 H0Y6Z0 ENST00000438317.5 ENST00000416206.5 ENST00000357394.8 [Q9Y282-3] A6PVJ2

ERGIC3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review