TM7SF2 | OmnibusX

Name	Number of supported studies	Average coverage
ciliated cell	9 studies	23% ± 8%	Explore
type II pneumocyte	4 studies	24% ± 11%	Explore
epithelial cell	3 studies	39% ± 13%	Explore
astrocyte	3 studies	30% ± 16%	Explore
Mueller cell	3 studies	40% ± 8%	Explore
oligodendrocyte precursor cell	3 studies	26% ± 11%	Explore
neuron	3 studies	39% ± 15%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of TM7SF2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	99%	1642.11	648 / 653	99%	69.78	601 / 605
brain	99%	1730.01	2618 / 2642	99%	59.08	695 / 705
prostate	95%	2983.42	232 / 245	100%	169.23	500 / 502
liver	100%	4108.73	226 / 226	94%	132.03	382 / 406
ovary	96%	3396.11	173 / 180	98%	62.30	420 / 430
adrenal gland	100%	21573.79	258 / 258	90%	140.50	206 / 230
breast	93%	2405.70	429 / 459	78%	33.23	869 / 1118
kidney	100%	1547.08	89 / 89	69%	30.00	623 / 901
pancreas	98%	3452.65	322 / 328	62%	14.85	111 / 178
intestine	77%	611.91	741 / 966	73%	19.35	383 / 527
stomach	92%	2165.43	329 / 359	51%	14.32	146 / 286
lung	64%	755.42	370 / 578	72%	25.65	832 / 1155
bladder	52%	401.29	11 / 21	77%	37.01	388 / 504
esophagus	65%	1286.52	945 / 1445	43%	10.35	78 / 183
skin	72%	3600.71	1305 / 1809	32%	8.87	150 / 472
ureter	0%	0	0 / 0	100%	113.50	1 / 1
heart	97%	2534.86	834 / 861	0%	0	0 / 0
uterus	35%	286.96	60 / 170	60%	26.04	276 / 459
adipose	93%	2585.98	1114 / 1204	0%	0	0 / 0
spleen	74%	490.85	178 / 241	0%	0	0 / 0
lymph node	0%	0	0 / 0	72%	21.13	21 / 29
tonsil	0%	0	0 / 0	51%	13.16	23 / 45
muscle	27%	162.48	213 / 803	0%	0	0 / 0
peripheral blood	25%	238.07	234 / 929	0%	0	0 / 0
blood vessel	15%	148.45	197 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	5%	0.88	4 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0006695	Biological process	cholesterol biosynthetic process
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0005783	Cellular component	endoplasmic reticulum
GO_0043235	Cellular component	receptor complex
GO_0005886	Cellular component	plasma membrane
GO_0005637	Cellular component	nuclear inner membrane
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0050661	Molecular function	NADP binding
GO_0005515	Molecular function	protein binding
GO_0050613	Molecular function	delta14-sterol reductase activity

Gene name	TM7SF2
Protein name	Delta(14)-sterol reductase TM7SF2 (Delta-14-SR) (EC 1.3.1.70) (3-beta-hydroxysterol Delta (14)-reductase) (Another new gene 1 protein) (C-14 sterol reductase) (C14SR) (Putative sterol reductase SR-1) (Sterol C14-reductase) (Transmembrane 7 superfamily member 2) Transmembrane 7 superfamily member 2
Synonyms	ANG1
Description	FUNCTION: Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis. .
Accessions	ENST00000525385.5 E9PQ50 H0YEN6 ENST00000528802.1 E9PLL1 ENST00000526809.5 O76062 E9PK81 ENST00000529601.5 E9PP79 E9PQZ7 E9PRQ1 ENST00000345348.9 [O76062-2] ENST00000530750.5 E9PLI3 ENST00000534371.5 ENST00000526085.5 E9PLS9 ENST00000524986.5 E9PS18 H0YDY5 ENST00000524690.5 ENST00000527968.5 ENST00000529414.5 E9PS09 H0YCI8 ENST00000279263.14 [O76062-1] ENST00000531321.5 ENST00000529292.5

TM7SF2 report