Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 9 studies | 25% ± 5% | |
| fibroblast | 7 studies | 20% ± 5% | |
| macrophage | 6 studies | 22% ± 4% | |
| microglial cell | 5 studies | 22% ± 6% | |
| astrocyte | 5 studies | 27% ± 8% | |
| glutamatergic neuron | 5 studies | 49% ± 27% | |
| oligodendrocyte | 5 studies | 22% ± 5% | |
| oligodendrocyte precursor cell | 5 studies | 26% ± 10% | |
| neuron | 4 studies | 21% ± 7% | |
| epithelial cell | 4 studies | 29% ± 8% | |
| myeloid cell | 3 studies | 17% ± 2% | |
| ciliated cell | 3 studies | 21% ± 1% | |
| lymphocyte | 3 studies | 19% ± 1% | |
| GABAergic neuron | 3 studies | 48% ± 4% | |
| pericyte | 3 studies | 27% ± 5% | |
| endothelial cell of lymphatic vessel | 3 studies | 21% ± 3% | |
| plasmacytoid dendritic cell | 3 studies | 24% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 3742.91 | 459 / 459 | 100% | 26.82 | 1117 / 1118 |
| prostate | 100% | 2960.98 | 245 / 245 | 100% | 20.14 | 501 / 502 |
| lung | 100% | 4612.51 | 578 / 578 | 100% | 21.90 | 1152 / 1155 |
| esophagus | 100% | 2670.05 | 1445 / 1445 | 99% | 22.68 | 182 / 183 |
| thymus | 100% | 3761.58 | 653 / 653 | 99% | 23.44 | 601 / 605 |
| brain | 99% | 2651.60 | 2619 / 2642 | 100% | 26.59 | 705 / 705 |
| uterus | 100% | 3394.48 | 170 / 170 | 99% | 21.86 | 455 / 459 |
| kidney | 100% | 2466.44 | 89 / 89 | 99% | 23.91 | 892 / 901 |
| bladder | 100% | 3054.81 | 21 / 21 | 99% | 18.18 | 497 / 504 |
| adrenal gland | 100% | 2582.22 | 258 / 258 | 97% | 22.18 | 224 / 230 |
| intestine | 100% | 3349.86 | 966 / 966 | 96% | 13.62 | 507 / 527 |
| pancreas | 98% | 1705.93 | 321 / 328 | 98% | 17.04 | 174 / 178 |
| stomach | 100% | 2333.94 | 359 / 359 | 95% | 15.09 | 273 / 286 |
| skin | 100% | 4180.19 | 1806 / 1809 | 95% | 24.89 | 448 / 472 |
| ovary | 100% | 2643.11 | 180 / 180 | 94% | 9.89 | 403 / 430 |
| liver | 100% | 2205.41 | 226 / 226 | 79% | 7.86 | 319 / 406 |
| blood vessel | 100% | 3723.49 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 25.34 | 29 / 29 |
| spleen | 100% | 4450.91 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 22.60 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 8.39 | 1 / 1 |
| adipose | 100% | 4093.29 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 99% | 1573.95 | 796 / 803 | 0% | 0 | 0 / 0 |
| heart | 99% | 2163.13 | 849 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 78% | 10.79 | 62 / 80 |
| peripheral blood | 60% | 1504.99 | 561 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0031092 | Cellular component | platelet alpha granule membrane |
| GO_0009986 | Cellular component | cell surface |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0015035 | Molecular function | protein-disulfide reductase activity |
| GO_0003756 | Molecular function | protein disulfide isomerase activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | TMX3 |
| Protein name | protein disulfide-isomerase (EC 5.3.4.1) Thioredoxin related transmembrane protein 3 Protein disulfide-isomerase TMX3 (EC 5.3.4.1) (Thioredoxin domain-containing protein 10) (Thioredoxin-related transmembrane protein 3) |
| Synonyms | TXNDC10 KIAA1830 |
| Description | FUNCTION: Probable disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. May act as a dithiol oxidase . Acts as a regulator of endoplasmic reticulum-mitochondria contact sites via its ability to regulate redox signals . . |
| Accessions | ENST00000565918.5 H3BVI1 H3BPB3 Q96JJ7 ENST00000569053.5 ENST00000564008.5 ENST00000564631.5 H3BT89 ENST00000569982.3 ENST00000299608.7 [Q96JJ7-1] H3BRY0 Q3B7X1 ENST00000562706.5 [Q96JJ7-2] ENST00000443099.6 B4DIE3 |