AVPR2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of AVPR2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of AVPR2 at tissue level.

III. Associated gene sets

GO_0008285Biological processnegative regulation of cell population proliferation
GO_0007188Biological processadenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO_0034097Biological processresponse to cytokine
GO_0010628Biological processpositive regulation of gene expression
GO_0045907Biological processpositive regulation of vasoconstriction
GO_1902533Biological processpositive regulation of intracellular signal transduction
GO_0032870Biological processcellular response to hormone stimulus
GO_0001992Biological processregulation of systemic arterial blood pressure by vasopressin
GO_0007599Biological processhemostasis
GO_0007190Biological processactivation of adenylate cyclase activity
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0003084Biological processpositive regulation of systemic arterial blood pressure
GO_0003092Biological processrenal water retention
GO_0008284Biological processpositive regulation of cell population proliferation
GO_0021537Biological processtelencephalon development
GO_0005886Cellular componentplasma membrane
GO_0030139Cellular componentendocytic vesicle
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0016020Cellular componentmembrane
GO_0030669Cellular componentclathrin-coated endocytic vesicle membrane
GO_0005794Cellular componentGolgi apparatus
GO_0005783Cellular componentendoplasmic reticulum
GO_0005768Cellular componentendosome
GO_0042277Molecular functionpeptide binding
GO_0005000Molecular functionvasopressin receptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameAVPR2
Protein nameVasopressin V2 receptor (V2R) (AVPR V2) (Antidiuretic hormone receptor) (Renal-type arginine vasopressin receptor)
Vasopressin V2 receptor
Arginine vasopressin receptor 2
SynonymsV2R
DIR3
ADHR
DIR
DescriptionFUNCTION: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption. .

FUNCTION: Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. .

AccessionsENST00000434679.6
ENST00000646375.2 [P30518-1]
ENST00000337474.5 [P30518-1]
ENST00000430697.1
C9JV81
ENST00000370049.1 [P30518-2]
P30518
F8WET1