Name | Number of supported studies | Average coverage | |
---|---|---|---|
classical monocyte | 20 studies | 27% ± 13% | |
monocyte | 11 studies | 25% ± 10% | |
epithelial cell | 11 studies | 36% ± 18% | |
type II pneumocyte | 10 studies | 35% ± 15% | |
endothelial cell | 10 studies | 21% ± 5% | |
type I pneumocyte | 8 studies | 29% ± 11% | |
non-classical monocyte | 8 studies | 31% ± 14% | |
adipocyte | 8 studies | 22% ± 4% | |
respiratory goblet cell | 7 studies | 26% ± 18% | |
basal cell | 7 studies | 36% ± 14% | |
ciliated cell | 7 studies | 34% ± 16% | |
fibroblast | 7 studies | 20% ± 6% | |
kidney loop of Henle epithelial cell | 6 studies | 23% ± 5% | |
enterocyte | 6 studies | 31% ± 12% | |
pericyte | 6 studies | 18% ± 2% | |
conventional dendritic cell | 5 studies | 33% ± 13% | |
goblet cell | 5 studies | 28% ± 7% | |
hepatocyte | 5 studies | 45% ± 23% | |
macrophage | 5 studies | 23% ± 7% | |
squamous epithelial cell | 4 studies | 47% ± 21% | |
neuron | 4 studies | 26% ± 12% | |
myeloid cell | 4 studies | 29% ± 13% | |
club cell | 4 studies | 29% ± 15% | |
secretory cell | 4 studies | 31% ± 17% | |
GABAergic neuron | 4 studies | 30% ± 11% | |
glutamatergic neuron | 4 studies | 39% ± 16% | |
hematopoietic precursor cell | 3 studies | 28% ± 5% | |
alveolar macrophage | 3 studies | 18% ± 2% | |
dendritic cell | 3 studies | 39% ± 20% | |
natural killer cell | 3 studies | 16% ± 0% | |
neutrophil | 3 studies | 23% ± 5% | |
transit amplifying cell | 3 studies | 22% ± 9% | |
mononuclear phagocyte | 3 studies | 27% ± 7% | |
astrocyte | 3 studies | 20% ± 2% | |
connective tissue cell | 3 studies | 18% ± 0% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
intestine | 100% | 7111.58 | 966 / 966 | 100% | 128.80 | 527 / 527 |
liver | 100% | 9873.46 | 226 / 226 | 100% | 144.39 | 406 / 406 |
lung | 100% | 7697.23 | 578 / 578 | 100% | 126.37 | 1155 / 1155 |
stomach | 100% | 8192.36 | 359 / 359 | 100% | 116.56 | 286 / 286 |
esophagus | 100% | 5976.40 | 1444 / 1445 | 100% | 129.67 | 183 / 183 |
breast | 100% | 5270.95 | 459 / 459 | 100% | 121.62 | 1117 / 1118 |
prostate | 100% | 4388.12 | 245 / 245 | 100% | 118.07 | 501 / 502 |
skin | 100% | 6354.89 | 1809 / 1809 | 100% | 147.77 | 471 / 472 |
uterus | 100% | 3483.39 | 170 / 170 | 100% | 103.05 | 458 / 459 |
pancreas | 100% | 3737.24 | 327 / 328 | 100% | 130.27 | 178 / 178 |
kidney | 100% | 8147.37 | 89 / 89 | 100% | 103.33 | 898 / 901 |
bladder | 100% | 4475.05 | 21 / 21 | 100% | 110.52 | 502 / 504 |
thymus | 100% | 4853.74 | 652 / 653 | 100% | 115.61 | 603 / 605 |
adrenal gland | 100% | 8475.97 | 258 / 258 | 99% | 97.20 | 228 / 230 |
ovary | 100% | 2920.38 | 180 / 180 | 99% | 58.35 | 426 / 430 |
brain | 99% | 4118.79 | 2612 / 2642 | 100% | 79.06 | 705 / 705 |
adipose | 100% | 6576.14 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 292.85 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 52.79 | 29 / 29 |
muscle | 100% | 7454.62 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 2747.97 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 114.42 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 108.58 | 1 / 1 |
blood vessel | 100% | 3746.19 | 1334 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 4969.91 | 923 / 929 | 0% | 0 | 0 / 0 |
heart | 94% | 4424.46 | 807 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006813 | Biological process | potassium ion transport |
GO_0006469 | Biological process | negative regulation of protein kinase activity |
GO_0006611 | Biological process | protein export from nucleus |
GO_0070885 | Biological process | negative regulation of calcineurin-NFAT signaling cascade |
GO_0031122 | Biological process | cytoplasmic microtubule organization |
GO_0010923 | Biological process | negative regulation of phosphatase activity |
GO_0071073 | Biological process | positive regulation of phospholipid biosynthetic process |
GO_0061025 | Biological process | membrane fusion |
GO_0042308 | Biological process | negative regulation of protein import into nucleus |
GO_0061024 | Biological process | membrane organization |
GO_0071468 | Biological process | cellular response to acidic pH |
GO_0032088 | Biological process | negative regulation of NF-kappaB transcription factor activity |
GO_0032417 | Biological process | positive regulation of sodium:proton antiporter activity |
GO_0001933 | Biological process | negative regulation of protein phosphorylation |
GO_0031397 | Biological process | negative regulation of protein ubiquitination |
GO_0051222 | Biological process | positive regulation of protein transport |
GO_0050821 | Biological process | protein stabilization |
GO_0022406 | Biological process | membrane docking |
GO_0007264 | Biological process | small GTPase-mediated signal transduction |
GO_0090314 | Biological process | positive regulation of protein targeting to membrane |
GO_0060050 | Biological process | positive regulation of protein glycosylation |
GO_0051453 | Biological process | regulation of intracellular pH |
GO_0031953 | Biological process | negative regulation of protein autophosphorylation |
GO_0001578 | Biological process | microtubule bundle formation |
GO_0035725 | Biological process | sodium ion transmembrane transport |
GO_0005886 | Cellular component | plasma membrane |
GO_0045121 | Cellular component | membrane raft |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005925 | Cellular component | focal adhesion |
GO_0000139 | Cellular component | Golgi membrane |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0015630 | Cellular component | microtubule cytoskeleton |
GO_0005793 | Cellular component | endoplasmic reticulum-Golgi intermediate compartment |
GO_0005737 | Cellular component | cytoplasm |
GO_0030133 | Cellular component | transport vesicle |
GO_1990351 | Cellular component | transporter complex |
GO_0005634 | Cellular component | nucleus |
GO_0004860 | Molecular function | protein kinase inhibitor activity |
GO_0019900 | Molecular function | kinase binding |
GO_0015385 | Molecular function | sodium:proton antiporter activity |
GO_0048306 | Molecular function | calcium-dependent protein binding |
GO_0015459 | Molecular function | potassium channel regulator activity |
GO_0008017 | Molecular function | microtubule binding |
GO_0005509 | Molecular function | calcium ion binding |
GO_0005515 | Molecular function | protein binding |
Gene name | CHP1 |
Protein name | Calcineurin B homologous protein 1 (Calcineurin B-like protein) (Calcium-binding protein CHP) (Calcium-binding protein p22) (EF-hand calcium-binding domain-containing protein p22) Calcineurin like EF-hand protein 1 |
Synonyms | CHP |
Description | FUNCTION: Calcium-binding protein involved in different processes such as regulation of vesicular trafficking, plasma membrane Na(+)/H(+) exchanger and gene transcription. Involved in the constitutive exocytic membrane traffic. Mediates the association between microtubules and membrane-bound organelles of the endoplasmic reticulum and Golgi apparatus and is also required for the targeting and fusion of transcytotic vesicles (TCV) with the plasma membrane. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Affects the pH sensitivity of SLC9A1/NHE1 by increasing its sensitivity at acidic pH. Required for the stabilization and localization of SLC9A1/NHE1 at the plasma membrane. Inhibits serum- and GTPase-stimulated Na(+)/H(+) exchange. Plays a role as an inhibitor of ribosomal RNA transcription by repressing the nucleolar UBF1 transcriptional activity. May sequester UBF1 in the nucleoplasm and limit its translocation to the nucleolus. Associates to the ribosomal gene promoter. Acts as a negative regulator of the calcineurin/NFAT signaling pathway. Inhibits NFAT nuclear translocation and transcriptional activity by suppressing the calcium-dependent calcineurin phosphatase activity. Also negatively regulates the kinase activity of the apoptosis-induced kinase STK17B. Inhibits both STK17B auto- and substrate-phosphorylations in a calcium-dependent manner. . |
Accessions | ENST00000560784.5 ENST00000392151.6 ENST00000560965.1 ENST00000560397.5 H0YLX1 Q99653 H0YLY7 H0YNG9 H0YKE7 ENST00000560411.5 ENST00000334660.10 F5GX29 |