UTP15 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of UTP15 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of UTP15 at tissue level.

III. Associated gene sets

GO_2000234Biological processpositive regulation of rRNA processing
GO_0045943Biological processpositive regulation of transcription by RNA polymerase I
GO_0006364Biological processrRNA processing
GO_0042274Biological processribosomal small subunit biogenesis
GO_0005730Cellular componentnucleolus
GO_0001650Cellular componentfibrillar center
GO_0005654Cellular componentnucleoplasm
GO_0005783Cellular componentendoplasmic reticulum
GO_0032040Cellular componentsmall-subunit processome
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameUTP15
Protein nameU3 small nucleolar RNA-associated protein 15 homolog
UTP15 small subunit processome component
Synonyms
DescriptionFUNCTION: Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I . Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome . .

AccessionsD6RF65
A0A1Y8EI88
ENST00000508491.1 [Q8TED0-3]
ENST00000509005.5
H0Y8P4
ENST00000508686.1
Q8TED0
ENST00000543251.5 [Q8TED0-2]
ENST00000296792.9 [Q8TED0-1]
ENST00000513824.5