Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 17 studies | 57% ± 18% | |
endothelial cell | 16 studies | 34% ± 16% | |
oligodendrocyte | 15 studies | 85% ± 8% | |
GABAergic neuron | 11 studies | 49% ± 20% | |
glutamatergic neuron | 11 studies | 43% ± 22% | |
fibroblast | 10 studies | 31% ± 10% | |
neuron | 7 studies | 36% ± 17% | |
ciliated cell | 7 studies | 38% ± 20% | |
endothelial cell of lymphatic vessel | 7 studies | 25% ± 11% | |
epithelial cell | 6 studies | 38% ± 22% | |
interneuron | 6 studies | 54% ± 20% | |
oligodendrocyte precursor cell | 6 studies | 31% ± 11% | |
basal cell | 5 studies | 48% ± 16% | |
club cell | 5 studies | 40% ± 16% | |
monocyte | 5 studies | 34% ± 9% | |
type I pneumocyte | 5 studies | 61% ± 6% | |
type II pneumocyte | 5 studies | 47% ± 6% | |
granule cell | 4 studies | 51% ± 14% | |
microglial cell | 4 studies | 51% ± 13% | |
pericyte | 4 studies | 28% ± 19% | |
dendritic cell | 4 studies | 20% ± 2% | |
vein endothelial cell | 4 studies | 27% ± 9% | |
Mueller cell | 4 studies | 56% ± 25% | |
amacrine cell | 4 studies | 71% ± 28% | |
retinal cone cell | 4 studies | 21% ± 6% | |
myofibroblast cell | 4 studies | 23% ± 5% | |
GABAergic interneuron | 3 studies | 41% ± 7% | |
glial cell | 3 studies | 42% ± 16% | |
macrophage | 3 studies | 38% ± 15% | |
progenitor cell | 3 studies | 45% ± 23% | |
adipocyte | 3 studies | 34% ± 23% | |
mesothelial cell | 3 studies | 35% ± 7% | |
GABAergic amacrine cell | 3 studies | 48% ± 13% | |
ON-bipolar cell | 3 studies | 56% ± 32% | |
glycinergic amacrine cell | 3 studies | 90% ± 8% | |
retina horizontal cell | 3 studies | 42% ± 25% | |
endothelial cell of vascular tree | 3 studies | 25% ± 3% | |
ependymal cell | 3 studies | 49% ± 23% | |
alveolar macrophage | 3 studies | 29% ± 6% | |
capillary endothelial cell | 3 studies | 26% ± 7% | |
respiratory goblet cell | 3 studies | 51% ± 18% | |
mucus secreting cell | 3 studies | 41% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 1608.94 | 245 / 245 | 100% | 15.29 | 501 / 502 |
lung | 100% | 1710.96 | 578 / 578 | 98% | 11.49 | 1131 / 1155 |
intestine | 100% | 3044.93 | 966 / 966 | 98% | 8.63 | 514 / 527 |
pancreas | 99% | 881.98 | 325 / 328 | 98% | 10.97 | 174 / 178 |
brain | 100% | 2074.11 | 2637 / 2642 | 97% | 13.46 | 682 / 705 |
esophagus | 98% | 1480.23 | 1421 / 1445 | 98% | 8.80 | 179 / 183 |
stomach | 100% | 2641.36 | 359 / 359 | 95% | 9.00 | 273 / 286 |
breast | 99% | 1421.59 | 456 / 459 | 95% | 10.06 | 1064 / 1118 |
bladder | 100% | 2425.05 | 21 / 21 | 93% | 9.18 | 470 / 504 |
kidney | 99% | 1363.19 | 88 / 89 | 92% | 13.09 | 831 / 901 |
uterus | 100% | 1145.96 | 170 / 170 | 91% | 9.92 | 418 / 459 |
thymus | 100% | 1820.47 | 653 / 653 | 88% | 6.55 | 534 / 605 |
ovary | 87% | 485.16 | 156 / 180 | 92% | 6.76 | 397 / 430 |
skin | 91% | 992.27 | 1649 / 1809 | 85% | 10.77 | 401 / 472 |
ureter | 0% | 0 | 0 / 0 | 100% | 3.75 | 1 / 1 |
adipose | 99% | 1078.45 | 1191 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 89% | 9.30 | 40 / 45 |
heart | 70% | 364.33 | 607 / 861 | 0% | 0 | 0 / 0 |
adrenal gland | 24% | 81.11 | 61 / 258 | 39% | 1.60 | 90 / 230 |
spleen | 59% | 230.25 | 143 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 51% | 262.72 | 676 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 45% | 1.46 | 13 / 29 |
peripheral blood | 42% | 276.93 | 386 / 929 | 0% | 0 | 0 / 0 |
liver | 6% | 21.26 | 13 / 226 | 15% | 0.74 | 60 / 406 |
muscle | 13% | 48.52 | 107 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 8% | 0.28 | 6 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0055074 | Biological process | calcium ion homeostasis |
GO_0035269 | Biological process | protein O-linked mannosylation |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0004169 | Molecular function | dolichyl-phosphate-mannose-protein mannosyltransferase activity |
GO_0005515 | Molecular function | protein binding |
GO_0000030 | Molecular function | mannosyltransferase activity |
Gene name | TMTC2 |
Protein name | Protein O-mannosyl-transferase TMTC2 (EC 2.4.1.109) (Transmembrane O-mannosyltransferase targeting cadherins 2) (Transmembrane and tetratricopeptide repeat-containing 2) dolichyl-phosphate-mannose--protein mannosyltransferase (EC 2.4.1.109) Transmembrane O-mannosyltransferase targeting cadherins 2 |
Synonyms | hCG_1730330 |
Description | FUNCTION: Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O-mannosyl-transferase on other proteins such as PDIA3. . |
Accessions | Q8N394 F8VSH2 ENST00000549919.1 ENST00000321196.8 A0A0B4J253 F8VRQ2 ENST00000548305.5 ENST00000546590.2 |