TMF1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	20 studies	22% ± 8%	Explore
natural killer cell	20 studies	22% ± 7%	Explore
ciliated cell	19 studies	40% ± 15%	Explore
fibroblast	17 studies	23% ± 7%	Explore
endothelial cell	15 studies	24% ± 8%	Explore
CD8-positive, alpha-beta T cell	14 studies	23% ± 6%	Explore
naive B cell	13 studies	24% ± 5%	Explore
regulatory T cell	13 studies	21% ± 5%	Explore
CD4-positive, alpha-beta T cell	12 studies	23% ± 5%	Explore
pericyte	11 studies	23% ± 8%	Explore
gamma-delta T cell	11 studies	25% ± 7%	Explore
T cell	10 studies	22% ± 8%	Explore
mast cell	10 studies	23% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	25% ± 7%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	23% ± 7%	Explore
memory B cell	10 studies	20% ± 3%	Explore
classical monocyte	9 studies	23% ± 8%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	22% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell	9 studies	23% ± 7%	Explore
mature NK T cell	9 studies	22% ± 6%	Explore
macrophage	9 studies	20% ± 5%	Explore
smooth muscle cell	8 studies	19% ± 3%	Explore
epithelial cell	8 studies	36% ± 19%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	8 studies	22% ± 5%	Explore
plasmacytoid dendritic cell	8 studies	20% ± 6%	Explore
mucosal invariant T cell	7 studies	20% ± 3%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	23% ± 5%	Explore
microglial cell	6 studies	20% ± 5%	Explore
basal cell	6 studies	28% ± 10%	Explore
myofibroblast cell	6 studies	20% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	6 studies	21% ± 3%	Explore
plasma cell	5 studies	28% ± 11%	Explore
leukocyte	5 studies	22% ± 4%	Explore
non-classical monocyte	5 studies	26% ± 9%	Explore
astrocyte	5 studies	25% ± 7%	Explore
glutamatergic neuron	5 studies	40% ± 15%	Explore
oligodendrocyte	5 studies	22% ± 5%	Explore
monocyte	4 studies	18% ± 2%	Explore
endothelial cell of lymphatic vessel	4 studies	19% ± 1%	Explore
type I pneumocyte	4 studies	22% ± 2%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	20% ± 4%	Explore
retinal cone cell	4 studies	25% ± 4%	Explore
retinal rod cell	4 studies	17% ± 1%	Explore
secretory cell	4 studies	23% ± 7%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	27% ± 9%	Explore
GABAergic neuron	4 studies	37% ± 12%	Explore
oligodendrocyte precursor cell	4 studies	27% ± 7%	Explore
dendritic cell	4 studies	31% ± 15%	Explore
goblet cell	4 studies	35% ± 18%	Explore
interneuron	4 studies	37% ± 17%	Explore
ionocyte	3 studies	32% ± 4%	Explore
respiratory goblet cell	3 studies	28% ± 8%	Explore
squamous epithelial cell	3 studies	41% ± 23%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	22% ± 4%	Explore
conventional dendritic cell	3 studies	32% ± 15%	Explore
plasmablast	3 studies	44% ± 15%	Explore
precursor B cell	3 studies	27% ± 4%	Explore
club cell	3 studies	28% ± 1%	Explore
retina horizontal cell	3 studies	18% ± 2%	Explore
lymphocyte	3 studies	30% ± 9%	Explore
innate lymphoid cell	3 studies	21% ± 6%	Explore
pancreatic A cell	3 studies	38% ± 16%	Explore
pancreatic ductal cell	3 studies	38% ± 17%	Explore
abnormal cell	3 studies	19% ± 5%	Explore
connective tissue cell	3 studies	22% ± 3%	Explore
granulocyte	3 studies	19% ± 3%	Explore
T follicular helper cell	3 studies	24% ± 3%	Explore
neuron	3 studies	24% ± 6%	Explore
double negative thymocyte	3 studies	27% ± 8%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	10 studies	26% ± 10%	Explore
lung	7 studies	26% ± 6%	Explore
brain	7 studies	31% ± 11%	Explore
eye	5 studies	22% ± 8%	Explore
bone marrow	3 studies	18% ± 2%	Explore
uterus	3 studies	28% ± 12%	Explore
intestine	3 studies	21% ± 4%	Explore
liver	3 studies	21% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2303.09	1445 / 1445	100%	20.27	183 / 183
ovary	100%	2933.42	180 / 180	100%	13.17	430 / 430
lung	100%	3252.83	577 / 578	100%	17.09	1155 / 1155
breast	100%	2989.14	459 / 459	100%	25.15	1116 / 1118
prostate	100%	2678.84	245 / 245	100%	21.92	501 / 502
pancreas	100%	2001.92	328 / 328	99%	17.59	177 / 178
bladder	100%	2387.24	21 / 21	99%	15.40	500 / 504
thymus	100%	3154.06	653 / 653	99%	21.02	600 / 605
stomach	100%	2026.08	359 / 359	99%	18.59	283 / 286
intestine	100%	2690.94	966 / 966	99%	17.39	520 / 527
adrenal gland	100%	2222.15	258 / 258	98%	13.13	226 / 230
uterus	100%	3032.61	170 / 170	98%	14.87	450 / 459
brain	98%	1415.69	2592 / 2642	99%	12.65	701 / 705
kidney	100%	1700.78	89 / 89	97%	14.74	878 / 901
skin	100%	2913.30	1807 / 1809	90%	15.75	427 / 472
liver	99%	1163.92	224 / 226	88%	6.73	356 / 406
adipose	100%	2890.33	1204 / 1204	0%	0	0 / 0
blood vessel	100%	3112.70	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	13.40	29 / 29
muscle	100%	2005.64	803 / 803	0%	0	0 / 0
spleen	100%	2352.49	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	5.77	1 / 1
tonsil	0%	0	0 / 0	96%	11.85	43 / 45
heart	95%	1408.42	819 / 861	0%	0	0 / 0
peripheral blood	87%	1883.14	811 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	41%	2.86	33 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0010629	Biological process	negative regulation of gene expression
GO_0007289	Biological process	spermatid nucleus differentiation
GO_0030317	Biological process	flagellated sperm motility
GO_0032275	Biological process	luteinizing hormone secretion
GO_0001675	Biological process	acrosome assembly
GO_1904036	Biological process	negative regulation of epithelial cell apoptotic process
GO_0042742	Biological process	defense response to bacterium
GO_1904019	Biological process	epithelial cell apoptotic process
GO_2000845	Biological process	positive regulation of testosterone secretion
GO_0001819	Biological process	positive regulation of cytokine production
GO_0033327	Biological process	Leydig cell differentiation
GO_0030521	Biological process	androgen receptor signaling pathway
GO_0061136	Biological process	regulation of proteasomal protein catabolic process
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0005794	Cellular component	Golgi apparatus
GO_0000139	Cellular component	Golgi membrane
GO_0005783	Cellular component	endoplasmic reticulum
GO_0005829	Cellular component	cytosol
GO_0005634	Cellular component	nucleus
GO_0003677	Molecular function	DNA binding
GO_0050681	Molecular function	nuclear androgen receptor binding
GO_0030374	Molecular function	nuclear receptor coactivator activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	TMF1
Protein name	TATA element modulatory factor 1 TMF1 protein TATA element modulatory factor (TMF) (Androgen receptor coactivator 160 kDa protein) (Androgen receptor-associated protein of 160 kDa)
Synonyms	ARA160
Description	FUNCTION: Potential coactivator of the androgen receptor. Mediates STAT3 degradation. May play critical roles in two RAB6-dependent retrograde transport processes: one from endosomes to the Golgi and the other from the Golgi to the ER. This protein binds the HIV-1 TATA element and inhibits transcriptional activation by the TATA-binding protein (TBP). .
Accessions	A0A2R8Y7M0 ENST00000488010.5 Q6PII6 F8WF45 ENST00000646304.1 ENST00000646708.1 [P82094-2] ENST00000398559.7 [P82094-1] P82094

TMF1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review