Name | Number of supported studies | Average coverage | |
---|---|---|---|
type I pneumocyte | 9 studies | 33% ± 14% | |
type II pneumocyte | 8 studies | 47% ± 17% | |
endothelial cell of lymphatic vessel | 7 studies | 27% ± 8% | |
microglial cell | 7 studies | 34% ± 11% | |
GABAergic neuron | 6 studies | 35% ± 17% | |
podocyte | 5 studies | 43% ± 11% | |
endothelial cell | 5 studies | 29% ± 13% | |
Mueller cell | 5 studies | 50% ± 16% | |
astrocyte | 4 studies | 28% ± 11% | |
glutamatergic neuron | 4 studies | 47% ± 17% | |
plasmacytoid dendritic cell | 4 studies | 21% ± 4% | |
kidney loop of Henle epithelial cell | 4 studies | 41% ± 14% | |
epithelial cell | 3 studies | 39% ± 15% | |
oligodendrocyte precursor cell | 3 studies | 29% ± 7% | |
macrophage | 3 studies | 21% ± 6% | |
fibroblast | 3 studies | 31% ± 10% | |
interneuron | 3 studies | 48% ± 21% | |
epithelial cell of proximal tubule | 3 studies | 37% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 100% | 5301.90 | 89 / 89 | 96% | 84.94 | 867 / 901 |
prostate | 100% | 3648.98 | 244 / 245 | 81% | 52.52 | 406 / 502 |
uterus | 99% | 2563.09 | 169 / 170 | 68% | 31.40 | 314 / 459 |
esophagus | 100% | 1667.65 | 1439 / 1445 | 65% | 33.57 | 119 / 183 |
lung | 96% | 2489.61 | 554 / 578 | 65% | 30.53 | 748 / 1155 |
adrenal gland | 100% | 6279.51 | 258 / 258 | 43% | 15.99 | 99 / 230 |
ovary | 100% | 2560.91 | 180 / 180 | 42% | 8.11 | 179 / 430 |
stomach | 91% | 1660.38 | 328 / 359 | 41% | 7.54 | 117 / 286 |
bladder | 90% | 1530.38 | 19 / 21 | 41% | 10.49 | 205 / 504 |
skin | 96% | 1977.93 | 1728 / 1809 | 34% | 13.71 | 161 / 472 |
intestine | 89% | 2683.81 | 858 / 966 | 38% | 6.29 | 198 / 527 |
breast | 87% | 814.28 | 398 / 459 | 21% | 4.01 | 238 / 1118 |
pancreas | 23% | 116.83 | 76 / 328 | 80% | 18.34 | 143 / 178 |
thymus | 76% | 474.27 | 495 / 653 | 25% | 8.47 | 154 / 605 |
spleen | 100% | 8584.13 | 241 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 95% | 1376.57 | 1262 / 1335 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 82% | 73.10 | 37 / 45 |
adipose | 74% | 550.88 | 895 / 1204 | 0% | 0 | 0 / 0 |
brain | 23% | 144.69 | 604 / 2642 | 32% | 5.30 | 224 / 705 |
heart | 42% | 268.64 | 364 / 861 | 0% | 0 | 0 / 0 |
liver | 33% | 195.18 | 75 / 226 | 6% | 1.59 | 24 / 406 |
lymph node | 0% | 0 | 0 / 0 | 10% | 1.86 | 3 / 29 |
peripheral blood | 9% | 216.27 | 88 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 5% | 0.62 | 4 / 80 |
muscle | 2% | 10.49 | 17 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0019511 | Biological process | peptidyl-proline hydroxylation |
GO_0008285 | Biological process | negative regulation of cell population proliferation |
GO_0032963 | Biological process | collagen metabolic process |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0005604 | Cellular component | basement membrane |
GO_0005788 | Cellular component | endoplasmic reticulum lumen |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0016529 | Cellular component | sarcoplasmic reticulum |
GO_0005506 | Molecular function | iron ion binding |
GO_0031418 | Molecular function | L-ascorbic acid binding |
GO_0019797 | Molecular function | procollagen-proline 3-dioxygenase activity |
Gene name | P3H2 |
Protein name | Prolyl 3-hydroxylase 2 Prolyl 3-hydroxylase 2 (EC 1.14.11.7) (Leprecan-like protein 1) (Myxoid liposarcoma-associated protein 4) Alternative protein LEPREL1 |
Synonyms | MLAT4 LEPREL1 |
Description | FUNCTION: Prolyl 3-hydroxylase that catalyzes the post-translational formation of 3-hydroxyproline on collagens . Contributes to proline 3-hydroxylation of collagen COL4A1 and COL1A1 in tendons, the eye sclera and in the eye lens capsule (By similarity). Has high activity with the type IV collagen COL4A1, and lower activity with COL1A1 . Catalyzes hydroxylation of the first Pro in Gly-Pro-Hyp sequences where Hyp is 4-hydroxyproline . Has no activity on substrates that lack 4-hydroxyproline in the third position . . |
Accessions | ENST00000444866.5 C9JSL4 ENST00000427335.6 [Q8IVL5-2] ENST00000426003.1 L8E8F3 C9J313 ENST00000319332.10 [Q8IVL5-1] Q8IVL5 |