TPST2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	34 studies	34% ± 12%	Explore
endothelial cell	31 studies	25% ± 9%	Explore
CD8-positive, alpha-beta T cell	18 studies	25% ± 9%	Explore
mast cell	17 studies	22% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	16 studies	35% ± 14%	Explore
mature NK T cell	16 studies	30% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	16 studies	42% ± 13%	Explore
gamma-delta T cell	13 studies	27% ± 8%	Explore
plasma cell	12 studies	30% ± 9%	Explore
platelet	10 studies	36% ± 12%	Explore
capillary endothelial cell	10 studies	29% ± 7%	Explore
vein endothelial cell	10 studies	30% ± 15%	Explore
CD8-positive, alpha-beta memory T cell	8 studies	24% ± 9%	Explore
macrophage	8 studies	23% ± 4%	Explore
endothelial cell of lymphatic vessel	7 studies	22% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	6 studies	25% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	31% ± 7%	Explore
megakaryocyte	6 studies	66% ± 19%	Explore
endothelial cell of vascular tree	6 studies	23% ± 4%	Explore
T cell	6 studies	19% ± 4%	Explore
endothelial cell of artery	6 studies	31% ± 11%	Explore
mucosal invariant T cell	6 studies	18% ± 2%	Explore
plasmacytoid dendritic cell	6 studies	21% ± 4%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	25% ± 7%	Explore
lymphocyte	5 studies	21% ± 3%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	27% ± 8%	Explore
classical monocyte	4 studies	27% ± 9%	Explore
exhausted T cell	4 studies	27% ± 6%	Explore
plasmablast	4 studies	32% ± 20%	Explore
IgG plasma cell	4 studies	20% ± 3%	Explore
myeloid cell	4 studies	24% ± 7%	Explore
epithelial cell	4 studies	33% ± 16%	Explore
innate lymphoid cell	4 studies	32% ± 16%	Explore
glutamatergic neuron	4 studies	32% ± 8%	Explore
hematopoietic precursor cell	3 studies	20% ± 6%	Explore
non-classical monocyte	3 studies	32% ± 8%	Explore
glomerular endothelial cell	3 studies	28% ± 6%	Explore
IgA plasma cell	3 studies	22% ± 1%	Explore
monocyte	3 studies	20% ± 4%	Explore
T follicular helper cell	3 studies	17% ± 1%	Explore
abnormal cell	3 studies	23% ± 10%	Explore
hepatocyte	3 studies	31% ± 19%	Explore
GABAergic neuron	3 studies	27% ± 5%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	37% ± 11%	Explore
hematopoietic stem cell	3 studies	32% ± 21%	Explore
astrocyte	3 studies	20% ± 4%	Explore
interneuron	3 studies	23% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	10 studies	22% ± 5%	Explore
liver	4 studies	23% ± 6%	Explore
lung	3 studies	21% ± 3%	Explore
brain	3 studies	33% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	4383.04	226 / 226	100%	33.27	406 / 406
pancreas	100%	23099.68	328 / 328	100%	22.44	178 / 178
thymus	100%	4318.74	653 / 653	100%	38.74	605 / 605
lung	100%	5196.45	578 / 578	100%	20.73	1154 / 1155
bladder	100%	1622.76	21 / 21	99%	19.19	501 / 504
uterus	100%	2179.61	170 / 170	99%	21.70	455 / 459
breast	100%	2563.65	459 / 459	99%	19.32	1104 / 1118
skin	100%	1748.21	1805 / 1809	99%	15.53	466 / 472
esophagus	98%	1375.13	1423 / 1445	100%	17.51	183 / 183
prostate	100%	1830.89	244 / 245	97%	12.01	485 / 502
ovary	96%	955.07	173 / 180	99%	14.92	424 / 430
intestine	95%	1154.74	918 / 966	99%	14.66	524 / 527
kidney	100%	2331.16	89 / 89	92%	15.19	832 / 901
brain	91%	1161.80	2413 / 2642	100%	17.53	705 / 705
stomach	84%	756.62	300 / 359	99%	14.77	284 / 286
adrenal gland	100%	3502.87	258 / 258	71%	7.96	164 / 230
adipose	100%	2584.86	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	25.75	29 / 29
spleen	100%	3971.84	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	20.15	45 / 45
ureter	0%	0	0 / 0	100%	6.19	1 / 1
peripheral blood	100%	6557.03	928 / 929	0%	0	0 / 0
muscle	100%	2404.25	799 / 803	0%	0	0 / 0
blood vessel	99%	1509.19	1319 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	99%	19.66	79 / 80
heart	98%	1729.13	847 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006478	Biological process	peptidyl-tyrosine sulfation
GO_0050427	Biological process	3'-phosphoadenosine 5'-phosphosulfate metabolic process
GO_0000139	Cellular component	Golgi membrane
GO_0005783	Cellular component	endoplasmic reticulum
GO_0005794	Cellular component	Golgi apparatus
GO_0042803	Molecular function	protein homodimerization activity
GO_0008476	Molecular function	protein-tyrosine sulfotransferase activity

IV. Literature review

[source]

Gene name	TPST2
Protein name	Protein-tyrosine sulfotransferase 2 (EC 2.8.2.20) (Tyrosylprotein sulfotransferase 2) (TPST-2) Protein-tyrosine sulfotransferase (EC 2.8.2.20) Tyrosylprotein sulfotransferase 2
Synonyms
Description	FUNCTION: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate. . FUNCTION: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate. . FUNCTION: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate. . FUNCTION: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate. .
Accessions	ENST00000398110.6 B1AHK0 B1AHJ5 B1AHJ9 ENST00000442495.5 ENST00000440953.5 O60704 ENST00000445720.1 B1AHJ7 B1AHJ6 B1AHJ8 ENST00000454778.6 ENST00000338754.9 ENST00000403880.5 ENST00000453117.1 ENST00000450022.1

TPST2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review