ATP10B | OmnibusX

Name	Number of supported studies	Average coverage
oligodendrocyte	16 studies	53% ± 19%	Explore
oligodendrocyte precursor cell	15 studies	46% ± 19%	Explore
astrocyte	9 studies	30% ± 15%	Explore
epithelial cell	5 studies	25% ± 7%	Explore
squamous epithelial cell	4 studies	28% ± 14%	Explore
respiratory goblet cell	3 studies	23% ± 6%	Explore
intestinal crypt stem cell	3 studies	23% ± 6%	Explore

Name	Number of supported studies	Average coverage
brain	10 studies	29% ± 15%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
intestine	52%	3297.40	506 / 966	94%	49.86	497 / 527
pancreas	72%	662.04	237 / 328	74%	13.60	131 / 178
brain	92%	879.61	2423 / 2642	50%	3.50	349 / 705
stomach	36%	238.88	131 / 359	87%	43.35	250 / 286
skin	71%	1806.98	1289 / 1809	50%	5.47	236 / 472
esophagus	40%	786.40	573 / 1445	67%	22.99	122 / 183
bladder	10%	30.33	2 / 21	46%	15.97	233 / 504
tonsil	0%	0	0 / 0	44%	8.41	20 / 45
lung	1%	8.48	5 / 578	35%	5.93	402 / 1155
uterus	1%	14.36	2 / 170	29%	3.42	134 / 459
ovary	0%	0	0 / 180	19%	1.36	80 / 430
thymus	1%	4.68	7 / 653	13%	2.88	81 / 605
liver	0%	1.61	1 / 226	3%	0.39	11 / 406
breast	1%	19.01	5 / 459	1%	0.05	13 / 1118
adipose	2%	9.04	24 / 1204	0%	0	0 / 0
blood vessel	2%	6.94	23 / 1335	0%	0	0 / 0
prostate	2%	5.02	4 / 245	0%	0	0 / 502
kidney	0%	0	0 / 89	1%	0.09	5 / 901
adrenal gland	0%	0	0 / 258	0%	0.02	1 / 230
muscle	0%	0.52	1 / 803	0%	0	0 / 0
heart	0%	0.39	1 / 861	0%	0	0 / 0
peripheral blood	0%	0.52	1 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0097212	Biological process	lysosomal membrane organization
GO_0045332	Biological process	phospholipid translocation
GO_1990531	Cellular component	phospholipid-translocating ATPase complex
GO_0005783	Cellular component	endoplasmic reticulum
GO_0031902	Cellular component	late endosome membrane
GO_0016020	Cellular component	membrane
GO_0005886	Cellular component	plasma membrane
GO_0005765	Cellular component	lysosomal membrane
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0140345	Molecular function	phosphatidylcholine flippase activity
GO_0005524	Molecular function	ATP binding
GO_0005515	Molecular function	protein binding
GO_0140351	Molecular function	glycosylceramide flippase activity
GO_0016887	Molecular function	ATP hydrolysis activity
GO_0000287	Molecular function	magnesium ion binding
GO_0140326	Molecular function	ATPase-coupled intramembrane lipid transporter activity

Gene name	ATP10B
Protein name	ATP10B protein (ATPase phospholipid transporting 10B (putative)) Phospholipid-transporting ATPase (EC 7.6.2.1) Phospholipid-transporting ATPase VB (EC 7.6.2.1) (ATPase class V type 10B) (P4-ATPase flippase complex alpha subunit ATP10B)
Synonyms	KIAA0715 hCG_1979529 ATPVB
Description	FUNCTION: Catalytic component of a P4-ATPase flippase complex, which catalyzes the hydrolysis of ATP coupled to the transport of glucosylceramide (GlcCer) from the outer to the inner leaflet of lysosome membranes. Plays an important role in the maintenance of lysosome membrane integrity and function in cortical neurons. .
Accessions	ENST00000520108.1 Q2YDW8 O94823 ENST00000642502.1 A0A2R8YDI5 ENST00000327245.10 [O94823-1]

ATP10B report