EEF1D | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	49 studies	84% ± 19%	Explore
natural killer cell	45 studies	78% ± 21%	Explore
endothelial cell	43 studies	64% ± 24%	Explore
macrophage	42 studies	68% ± 23%	Explore
fibroblast	41 studies	73% ± 25%	Explore
T cell	40 studies	74% ± 27%	Explore
CD8-positive, alpha-beta T cell	39 studies	81% ± 20%	Explore
CD4-positive, alpha-beta T cell	36 studies	85% ± 19%	Explore
pericyte	34 studies	74% ± 25%	Explore
smooth muscle cell	29 studies	73% ± 27%	Explore
conventional dendritic cell	29 studies	88% ± 8%	Explore
classical monocyte	27 studies	83% ± 12%	Explore
regulatory T cell	27 studies	90% ± 11%	Explore
epithelial cell	27 studies	70% ± 26%	Explore
dendritic cell	26 studies	76% ± 25%	Explore
plasma cell	26 studies	82% ± 20%	Explore
plasmacytoid dendritic cell	26 studies	91% ± 7%	Explore
monocyte	25 studies	69% ± 27%	Explore
endothelial cell of lymphatic vessel	24 studies	73% ± 25%	Explore
non-classical monocyte	24 studies	88% ± 10%	Explore
mast cell	23 studies	65% ± 23%	Explore
mature NK T cell	23 studies	79% ± 18%	Explore
basal cell	22 studies	78% ± 23%	Explore
gamma-delta T cell	21 studies	83% ± 22%	Explore
memory B cell	21 studies	89% ± 18%	Explore
naive B cell	20 studies	88% ± 17%	Explore
connective tissue cell	19 studies	79% ± 21%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	18 studies	90% ± 13%	Explore
mucosal invariant T cell	17 studies	89% ± 13%	Explore
ciliated cell	17 studies	47% ± 15%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	79% ± 22%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	15 studies	91% ± 20%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	85% ± 11%	Explore
myofibroblast cell	15 studies	78% ± 23%	Explore
myeloid cell	15 studies	68% ± 25%	Explore
neutrophil	14 studies	48% ± 28%	Explore
capillary endothelial cell	14 studies	56% ± 21%	Explore
endothelial cell of artery	14 studies	63% ± 22%	Explore
vein endothelial cell	13 studies	68% ± 22%	Explore
endothelial cell of vascular tree	13 studies	72% ± 25%	Explore
effector memory CD8-positive, alpha-beta T cell	12 studies	82% ± 19%	Explore
innate lymphoid cell	12 studies	86% ± 8%	Explore
plasmablast	12 studies	87% ± 9%	Explore
CD4-positive, alpha-beta memory T cell	12 studies	87% ± 12%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	89% ± 11%	Explore
secretory cell	12 studies	82% ± 16%	Explore
club cell	11 studies	68% ± 28%	Explore
goblet cell	11 studies	62% ± 23%	Explore
type I pneumocyte	10 studies	51% ± 23%	Explore
type II pneumocyte	10 studies	67% ± 30%	Explore
T follicular helper cell	10 studies	93% ± 5%	Explore
leukocyte	10 studies	76% ± 25%	Explore
progenitor cell	10 studies	80% ± 24%	Explore
mesothelial cell	10 studies	81% ± 21%	Explore
erythrocyte	10 studies	62% ± 22%	Explore
abnormal cell	9 studies	79% ± 16%	Explore
IgG plasma cell	9 studies	73% ± 22%	Explore
astrocyte	9 studies	36% ± 17%	Explore
microglial cell	9 studies	54% ± 26%	Explore
platelet	8 studies	45% ± 25%	Explore
IgA plasma cell	8 studies	73% ± 25%	Explore
ionocyte	7 studies	71% ± 12%	Explore
respiratory goblet cell	7 studies	63% ± 24%	Explore
effector CD4-positive, alpha-beta T cell	7 studies	83% ± 24%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	92% ± 6%	Explore
mononuclear phagocyte	7 studies	73% ± 24%	Explore
epithelial cell of proximal tubule	7 studies	62% ± 23%	Explore
enterocyte	7 studies	62% ± 24%	Explore
hematopoietic stem cell	7 studies	93% ± 5%	Explore
precursor B cell	7 studies	79% ± 27%	Explore
neuron	7 studies	56% ± 16%	Explore
alveolar macrophage	6 studies	69% ± 20%	Explore
hematopoietic precursor cell	6 studies	73% ± 30%	Explore
kidney loop of Henle epithelial cell	6 studies	57% ± 18%	Explore
renal alpha-intercalated cell	6 studies	84% ± 6%	Explore
transit amplifying cell	6 studies	69% ± 22%	Explore
brush cell	6 studies	73% ± 16%	Explore
immature B cell	6 studies	92% ± 9%	Explore
oligodendrocyte	6 studies	27% ± 10%	Explore
intermediate monocyte	6 studies	79% ± 24%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	92% ± 7%	Explore
CD4-positive helper T cell	5 studies	86% ± 9%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	91% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	87% ± 6%	Explore
duct epithelial cell	5 studies	76% ± 29%	Explore
exhausted T cell	5 studies	94% ± 2%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	75% ± 16%	Explore
erythroblast	5 studies	67% ± 24%	Explore
intestinal crypt stem cell	5 studies	75% ± 30%	Explore
lymphocyte	5 studies	76% ± 27%	Explore
T-helper 17 cell	5 studies	93% ± 6%	Explore
group 3 innate lymphoid cell	5 studies	92% ± 4%	Explore
mucus secreting cell	5 studies	73% ± 27%	Explore
double negative thymocyte	5 studies	92% ± 4%	Explore
hepatocyte	5 studies	56% ± 25%	Explore
granulocyte	5 studies	77% ± 10%	Explore
oligodendrocyte precursor cell	5 studies	45% ± 24%	Explore
CD4-positive, alpha-beta cytotoxic T cell	4 studies	78% ± 24%	Explore
deuterosomal cell	4 studies	60% ± 16%	Explore
squamous epithelial cell	4 studies	51% ± 21%	Explore
pancreatic A cell	4 studies	55% ± 21%	Explore
type B pancreatic cell	4 studies	63% ± 20%	Explore
glomerular endothelial cell	4 studies	58% ± 16%	Explore
podocyte	4 studies	73% ± 17%	Explore
enteroendocrine cell	4 studies	73% ± 14%	Explore
retinal ganglion cell	4 studies	45% ± 29%	Explore
pro-B cell	4 studies	88% ± 3%	Explore
amacrine cell	4 studies	36% ± 14%	Explore
retinal pigment epithelial cell	4 studies	47% ± 26%	Explore
retinal rod cell	4 studies	29% ± 11%	Explore
adventitial cell	4 studies	76% ± 11%	Explore
adipocyte	4 studies	21% ± 6%	Explore
acinar cell	4 studies	67% ± 26%	Explore
muscle cell	4 studies	53% ± 21%	Explore
germinal center B cell	4 studies	85% ± 12%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	92% ± 8%	Explore
luminal cell of prostate epithelium	4 studies	79% ± 25%	Explore
IgM plasma cell	4 studies	72% ± 25%	Explore
glial cell	4 studies	57% ± 25%	Explore
melanocyte	4 studies	60% ± 30%	Explore
interneuron	4 studies	38% ± 25%	Explore
T-helper 1 cell	4 studies	96% ± 1%	Explore
hillock cell	3 studies	68% ± 29%	Explore
precursor cell	3 studies	93% ± 5%	Explore
monocyte-derived dendritic cell	3 studies	92% ± 9%	Explore
neural crest cell	3 studies	95% ± 3%	Explore
paneth cell	3 studies	82% ± 6%	Explore
retinal bipolar neuron	3 studies	35% ± 12%	Explore
OFF-bipolar cell	3 studies	23% ± 6%	Explore
renal principal cell	3 studies	64% ± 7%	Explore
thymocyte	3 studies	93% ± 5%	Explore
extravillous trophoblast	3 studies	85% ± 10%	Explore
placental villous trophoblast	3 studies	84% ± 7%	Explore
neuroendocrine cell	3 studies	62% ± 21%	Explore
Schwann cell	3 studies	62% ± 34%	Explore
retina horizontal cell	3 studies	36% ± 12%	Explore
retinal cone cell	3 studies	43% ± 13%	Explore
serous secreting cell	3 studies	85% ± 11%	Explore
tissue-resident macrophage	3 studies	59% ± 24%	Explore
follicular B cell	3 studies	87% ± 8%	Explore
intraepithelial lymphocyte	3 studies	90% ± 5%	Explore
Mueller cell	3 studies	57% ± 4%	Explore
cardiac muscle cell	3 studies	29% ± 13%	Explore
chondrocyte	3 studies	44% ± 28%	Explore
endothelial cell of sinusoid	3 studies	40% ± 28%	Explore
myoepithelial cell	3 studies	92% ± 2%	Explore
inflammatory macrophage	3 studies	71% ± 13%	Explore
pancreatic ductal cell	3 studies	72% ± 14%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	89% ± 8%	Explore
keratinocyte	3 studies	88% ± 10%	Explore
glutamatergic neuron	3 studies	30% ± 14%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	96% ± 1%	Explore
double-positive, alpha-beta thymocyte	3 studies	97% ± 1%	Explore
progenitor cell of mammary luminal epithelium	3 studies	97% ± 3%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	20 studies	67% ± 22%	Explore
peripheral blood	20 studies	87% ± 13%	Explore
intestine	12 studies	75% ± 20%	Explore
kidney	9 studies	68% ± 23%	Explore
eye	9 studies	37% ± 20%	Explore
brain	8 studies	39% ± 20%	Explore
liver	7 studies	67% ± 24%	Explore
lymph node	6 studies	88% ± 8%	Explore
pancreas	5 studies	60% ± 20%	Explore
bone marrow	5 studies	74% ± 22%	Explore
placenta	5 studies	60% ± 29%	Explore
uterus	5 studies	74% ± 25%	Explore
prostate	5 studies	65% ± 35%	Explore
breast	4 studies	88% ± 6%	Explore
heart	3 studies	36% ± 16%	Explore
adipose	3 studies	46% ± 30%	Explore
adrenal gland	3 studies	71% ± 24%	Explore
esophagus	3 studies	71% ± 22%	Explore
skin	3 studies	68% ± 30%	Explore
thymus	3 studies	74% ± 34%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	7297.30	1445 / 1445	100%	23.80	183 / 183
ovary	100%	13524.45	180 / 180	100%	35.91	430 / 430
pancreas	100%	9886.99	328 / 328	100%	24.11	178 / 178
prostate	100%	8795.59	245 / 245	100%	29.91	502 / 502
stomach	100%	6715.19	359 / 359	100%	25.55	286 / 286
lung	100%	6295.16	577 / 578	100%	23.79	1153 / 1155
intestine	100%	8306.82	966 / 966	100%	27.66	525 / 527
uterus	100%	9637.98	170 / 170	100%	25.95	457 / 459
breast	100%	8047.63	459 / 459	100%	30.02	1113 / 1118
thymus	100%	8299.67	653 / 653	99%	25.60	601 / 605
brain	99%	3618.77	2626 / 2642	100%	23.49	704 / 705
skin	100%	7808.93	1809 / 1809	99%	23.87	467 / 472
bladder	100%	8168.62	21 / 21	99%	25.57	498 / 504
kidney	100%	5984.91	89 / 89	99%	18.05	888 / 901
liver	100%	3578.42	226 / 226	98%	19.22	397 / 406
adrenal gland	100%	7908.80	258 / 258	95%	19.99	219 / 230
adipose	100%	7280.86	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	68.36	80 / 80
lymph node	0%	0	0 / 0	100%	34.30	29 / 29
muscle	100%	7332.22	803 / 803	0%	0	0 / 0
spleen	100%	8348.81	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	23.78	45 / 45
ureter	0%	0	0 / 0	100%	28.12	1 / 1
blood vessel	100%	6236.35	1334 / 1335	0%	0	0 / 0
peripheral blood	99%	6433.30	923 / 929	0%	0	0 / 0
heart	99%	5790.46	850 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006414	Biological process	translational elongation
GO_0071479	Biological process	cellular response to ionizing radiation
GO_0005853	Cellular component	eukaryotic translation elongation factor 1 complex
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005783	Cellular component	endoplasmic reticulum
GO_0005737	Cellular component	cytoplasm
GO_0001650	Cellular component	fibrillar center
GO_0005634	Cellular component	nucleus
GO_0045296	Molecular function	cadherin binding
GO_0003677	Molecular function	DNA binding
GO_0008135	Molecular function	translation factor activity, RNA binding
GO_0005085	Molecular function	guanyl-nucleotide exchange factor activity
GO_0003746	Molecular function	translation elongation factor activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	EEF1D
Protein name	Elongation factor 1-delta Elongation factor 1-delta (EF-1-delta) (Antigen NY-CO-4) Elongation factor 1-delta (Eukaryotic translation elongation factor 1 delta) Eukaryotic translation elongation factor 1 delta
Synonyms	EF1D
Description	FUNCTION: [Isoform 1]: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome.; FUNCTION: [Isoform 2]: Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE).
Accessions	E9PIZ1 ENST00000529007.5 ENST00000534380.6 [P29692-1] ENST00000634157.1 E9PM66 E9PQR8 ENST00000530445.6 [P29692-1] E9PNW6 ENST00000633339.1 E9PQC9 ENST00000525223.1 E9PK06 ENST00000524883.1 ENST00000633697.1 ENST00000526838.5 [P29692-4] E9PI39 ENST00000534804.5 E9PJ84 ENST00000632587.1 [P29692-1] ENST00000530191.6 [P29692-1] E9PRL0 ENST00000529832.5 ENST00000633090.1 ENST00000631875.1 ENST00000632241.1 ENST00000631863.1 ENST00000531670.5 E9PMW7 ENST00000631585.1 ENST00000528610.5 [P29692-3] ENST00000614575.4 [P29692-1] A0A087X1X7 ENST00000632965.1 [P29692-3] ENST00000526340.5 ENST00000423316.7 ENST00000633686.1 ENST00000533494 ENST00000530306.5 ENST00000618139.4 [P29692-2] ENST00000633396.1 ENST00000632733.1 ENST00000529272.5 [P29692-1] ENST00000633928.1 ENST00000533833.5 ENST00000419152.7 [P29692-1] E9PN71 E9PKH7 ENST00000633641.1 H0YCK7 ENST00000632626.1 ENST00000632675.1 [P29692-3] E9PJV8 ENST00000615698.4 [P29692-1] ENST00000615067.4 [P29692-1] ENST00000632659.1 ENST00000619198.2 ENST00000631688.1 ENST00000526135.5 Q9BW34 ENST00000532543.1 P29692 ENST00000531621.5 ENST00000631650.1 ENST00000531218.6 [P29692-1] E9PI93 ENST00000529516 ENST00000633259.1 E9PNC8 ENST00000633394.1 H0YE58 E9PL71 E9PL21 ENST00000524624.5 [P29692-3] ENST00000634156.1 ENST00000525261.5 ENST00000532596.5 ENST00000531218 ENST00000631850.1 ENST00000526710.1 ENST00000524397.5 ENST00000317198.10 [P29692-1] ENST00000530191 ENST00000631698.1 [P29692-4] A0A0J9YXU2 E9PKK3 ENST00000529516.6 [P29692-4] ENST00000395119.7 [P29692-1] E9PLS6 ENST00000442189.6 [P29692-2] ENST00000534377 ENST00000526133.1 E9PQ49 E9PIP5 ENST00000620155.3 [P29692-2] E9PLL8 ENST00000619144.4 [P29692-2] ENST00000632115.1 E9PL12 E9PRY8 ENST00000632238.1 ENST00000633476.1 ENST00000530616.5 E9PQZ1 ENST00000528303.5 ENST00000529576.5 ENST00000633887.1 ENST00000533749.5 ENST00000533494.6 [P29692-1] ENST00000530445 E9PLA1 ENST00000532741.5 ENST00000534377.6 [P29692-3] E9PK01 E9PJD0 E9PPY1 ENST00000528519.1 E9PPR1 ENST00000530545.5 E9PLT8 ENST00000633058.1 ENST00000531931.1 E9PN56 ENST00000633857.1 E9PN91 ENST00000531281.1 ENST00000618139 ENST00000631763.1 ENST00000632402.1 ENST00000524900.1 E9PK72 ENST00000534380 ENST00000632162.1 ENST00000531953.5 ENST00000632423.1 ENST00000532400.1 ENST00000528382.1 ENST00000534475.5 A0A8C8L741

EEF1D report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review