ATP11B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0034220Biological processmonoatomic ion transmembrane transport
GO_0006811Biological processmonoatomic ion transport
GO_0045332Biological processphospholipid translocation
GO_0015917Biological processaminophospholipid transport
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0055037Cellular componentrecycling endosome
GO_0031901Cellular componentearly endosome membrane
GO_0035577Cellular componentazurophil granule membrane
GO_0055038Cellular componentrecycling endosome membrane
GO_0005794Cellular componentGolgi apparatus
GO_0005637Cellular componentnuclear inner membrane
GO_1990531Cellular componentphospholipid-translocating ATPase complex
GO_0005783Cellular componentendoplasmic reticulum
GO_0090556Molecular functionphosphatidylserine floppase activity
GO_0015075Molecular functionmonoatomic ion transmembrane transporter activity
GO_0140326Molecular functionATPase-coupled intramembrane lipid transporter activity
GO_0000287Molecular functionmagnesium ion binding
GO_0090555Molecular functionphosphatidylethanolamine flippase activity
GO_0005524Molecular functionATP binding
GO_0005515Molecular functionprotein binding
GO_0016887Molecular functionATP hydrolysis activity

IV. Literature review

[source]
Gene nameATP11B
Protein nameATP11B protein
ATPase phospholipid transporting 11B (putative)
Phospholipid-transporting ATPase IF (EC 7.6.2.1) (ATPase IR) (ATPase class VI type 11B) (P4-ATPase flippase complex alpha subunit ATP11B)
Truncated ATPase 11B protein
Phospholipid-transporting ATPase (EC 7.6.2.1)
Alternative protein ATP11B
SynonymsKIAA0956
ATPIR
ATPIF
DescriptionFUNCTION: Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids, phosphatidylserines (PS) and phosphatidylethanolamines (PE), from the outer to the inner leaflet of intracellular membranes . May contribute to the maintenance of membrane lipid asymmetry in endosome compartment . .

AccessionsA0A0C4DG94
H7C575
ENST00000484691.1
H7C4W6
Q8N4L6
ENST00000493826.1
L8E9M9
ENST00000498086.5
ENST00000482070.1
Q9Y2G3
H0Y854
ENST00000466758.5
H7C4E6
ENST00000491699.6
ENST00000323116.10
A5XEH5
H0Y8C7