Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 15 studies | 30% ± 15% | |
microglial cell | 11 studies | 29% ± 11% | |
oligodendrocyte | 11 studies | 34% ± 11% | |
oligodendrocyte precursor cell | 10 studies | 28% ± 13% | |
T cell | 9 studies | 26% ± 8% | |
glutamatergic neuron | 9 studies | 40% ± 27% | |
macrophage | 9 studies | 32% ± 11% | |
adipocyte | 9 studies | 32% ± 9% | |
fibroblast | 8 studies | 24% ± 12% | |
mast cell | 8 studies | 23% ± 6% | |
astrocyte | 8 studies | 29% ± 13% | |
B cell | 7 studies | 23% ± 8% | |
epithelial cell | 7 studies | 32% ± 18% | |
GABAergic neuron | 7 studies | 39% ± 21% | |
natural killer cell | 6 studies | 27% ± 9% | |
CD8-positive, alpha-beta T cell | 6 studies | 22% ± 5% | |
interneuron | 6 studies | 36% ± 22% | |
myeloid cell | 6 studies | 23% ± 6% | |
dendritic cell | 6 studies | 24% ± 6% | |
CD16-negative, CD56-bright natural killer cell, human | 5 studies | 22% ± 6% | |
CD4-positive, alpha-beta T cell | 5 studies | 24% ± 6% | |
effector memory CD8-positive, alpha-beta T cell | 5 studies | 22% ± 7% | |
plasma cell | 5 studies | 35% ± 14% | |
ciliated cell | 5 studies | 22% ± 5% | |
CD8-positive, alpha-beta memory T cell | 5 studies | 18% ± 2% | |
endothelial cell of lymphatic vessel | 5 studies | 36% ± 8% | |
monocyte | 5 studies | 36% ± 9% | |
smooth muscle cell | 5 studies | 20% ± 3% | |
type I pneumocyte | 5 studies | 28% ± 9% | |
type II pneumocyte | 5 studies | 24% ± 7% | |
CD16-positive, CD56-dim natural killer cell, human | 4 studies | 22% ± 5% | |
neuron | 4 studies | 30% ± 13% | |
cardiac muscle cell | 4 studies | 28% ± 2% | |
lymphocyte | 4 studies | 39% ± 17% | |
retina horizontal cell | 4 studies | 27% ± 13% | |
retinal rod cell | 4 studies | 31% ± 5% | |
club cell | 4 studies | 25% ± 8% | |
pericyte | 4 studies | 27% ± 6% | |
classical monocyte | 3 studies | 23% ± 4% | |
GABAergic interneuron | 3 studies | 22% ± 5% | |
retinal cone cell | 3 studies | 27% ± 8% | |
gamma-delta T cell | 3 studies | 22% ± 4% | |
hepatocyte | 3 studies | 33% ± 21% | |
alveolar macrophage | 3 studies | 41% ± 11% | |
respiratory goblet cell | 3 studies | 28% ± 12% | |
basal cell | 3 studies | 34% ± 22% | |
goblet cell | 3 studies | 42% ± 32% | |
leukocyte | 3 studies | 43% ± 12% | |
transit amplifying cell | 3 studies | 36% ± 26% | |
granule cell | 3 studies | 21% ± 4% | |
plasmacytoid dendritic cell | 3 studies | 22% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 4824.90 | 1445 / 1445 | 99% | 65.25 | 182 / 183 |
prostate | 100% | 3251.21 | 245 / 245 | 99% | 55.59 | 497 / 502 |
lung | 100% | 4070.00 | 578 / 578 | 99% | 45.43 | 1142 / 1155 |
intestine | 100% | 3695.51 | 966 / 966 | 98% | 27.62 | 517 / 527 |
stomach | 100% | 4532.25 | 359 / 359 | 98% | 30.93 | 280 / 286 |
bladder | 100% | 3479.57 | 21 / 21 | 96% | 28.77 | 485 / 504 |
pancreas | 99% | 1936.06 | 326 / 328 | 97% | 26.96 | 172 / 178 |
thymus | 100% | 2571.51 | 652 / 653 | 94% | 19.54 | 569 / 605 |
uterus | 100% | 3663.14 | 170 / 170 | 92% | 31.96 | 424 / 459 |
kidney | 100% | 1772.10 | 89 / 89 | 90% | 19.55 | 807 / 901 |
skin | 100% | 5277.74 | 1809 / 1809 | 89% | 21.11 | 422 / 472 |
breast | 100% | 3338.86 | 459 / 459 | 86% | 20.56 | 964 / 1118 |
ovary | 100% | 3204.73 | 180 / 180 | 86% | 11.53 | 370 / 430 |
brain | 76% | 1004.07 | 1998 / 2642 | 83% | 9.18 | 583 / 705 |
liver | 96% | 1278.81 | 218 / 226 | 61% | 7.89 | 246 / 406 |
adrenal gland | 99% | 1657.17 | 255 / 258 | 57% | 5.77 | 131 / 230 |
blood vessel | 100% | 3197.37 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 3555.55 | 241 / 241 | 0% | 0 | 0 / 0 |
adipose | 100% | 3685.79 | 1203 / 1204 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 7690.43 | 919 / 929 | 0% | 0 | 0 / 0 |
muscle | 98% | 1569.42 | 790 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 48.99 | 43 / 45 |
lymph node | 0% | 0 | 0 / 0 | 93% | 18.10 | 27 / 29 |
heart | 92% | 1767.87 | 795 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 40% | 3.90 | 32 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0034220 | Biological process | monoatomic ion transmembrane transport |
GO_0006811 | Biological process | monoatomic ion transport |
GO_0045332 | Biological process | phospholipid translocation |
GO_0015917 | Biological process | aminophospholipid transport |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0055037 | Cellular component | recycling endosome |
GO_0031901 | Cellular component | early endosome membrane |
GO_0035577 | Cellular component | azurophil granule membrane |
GO_0055038 | Cellular component | recycling endosome membrane |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0005637 | Cellular component | nuclear inner membrane |
GO_1990531 | Cellular component | phospholipid-translocating ATPase complex |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0090556 | Molecular function | phosphatidylserine floppase activity |
GO_0015075 | Molecular function | monoatomic ion transmembrane transporter activity |
GO_0140326 | Molecular function | ATPase-coupled intramembrane lipid transporter activity |
GO_0000287 | Molecular function | magnesium ion binding |
GO_0090555 | Molecular function | phosphatidylethanolamine flippase activity |
GO_0005524 | Molecular function | ATP binding |
GO_0005515 | Molecular function | protein binding |
GO_0016887 | Molecular function | ATP hydrolysis activity |
Gene name | ATP11B |
Protein name | ATP11B protein ATPase phospholipid transporting 11B (putative) Phospholipid-transporting ATPase IF (EC 7.6.2.1) (ATPase IR) (ATPase class VI type 11B) (P4-ATPase flippase complex alpha subunit ATP11B) Truncated ATPase 11B protein Phospholipid-transporting ATPase (EC 7.6.2.1) Alternative protein ATP11B |
Synonyms | KIAA0956 ATPIR ATPIF |
Description | FUNCTION: Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids, phosphatidylserines (PS) and phosphatidylethanolamines (PE), from the outer to the inner leaflet of intracellular membranes . May contribute to the maintenance of membrane lipid asymmetry in endosome compartment . . |
Accessions | A0A0C4DG94 H7C575 ENST00000484691.1 H7C4W6 Q8N4L6 ENST00000493826.1 L8E9M9 ENST00000498086.5 ENST00000482070.1 Q9Y2G3 H0Y854 ENST00000466758.5 H7C4E6 ENST00000491699.6 ENST00000323116.10 A5XEH5 H0Y8C7 |