Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 15 studies | 30% ± 15% | |
| microglial cell | 11 studies | 29% ± 11% | |
| oligodendrocyte | 11 studies | 34% ± 11% | |
| oligodendrocyte precursor cell | 10 studies | 28% ± 13% | |
| T cell | 9 studies | 26% ± 8% | |
| glutamatergic neuron | 9 studies | 40% ± 27% | |
| macrophage | 9 studies | 32% ± 11% | |
| adipocyte | 9 studies | 32% ± 9% | |
| fibroblast | 8 studies | 24% ± 12% | |
| mast cell | 8 studies | 23% ± 6% | |
| astrocyte | 8 studies | 29% ± 13% | |
| B cell | 7 studies | 23% ± 8% | |
| epithelial cell | 7 studies | 32% ± 18% | |
| GABAergic neuron | 7 studies | 39% ± 21% | |
| natural killer cell | 6 studies | 27% ± 9% | |
| CD8-positive, alpha-beta T cell | 6 studies | 22% ± 5% | |
| interneuron | 6 studies | 36% ± 22% | |
| myeloid cell | 6 studies | 23% ± 6% | |
| dendritic cell | 6 studies | 24% ± 6% | |
| CD16-negative, CD56-bright natural killer cell, human | 5 studies | 22% ± 6% | |
| CD4-positive, alpha-beta T cell | 5 studies | 24% ± 6% | |
| effector memory CD8-positive, alpha-beta T cell | 5 studies | 22% ± 7% | |
| plasma cell | 5 studies | 35% ± 14% | |
| ciliated cell | 5 studies | 22% ± 5% | |
| CD8-positive, alpha-beta memory T cell | 5 studies | 18% ± 2% | |
| endothelial cell of lymphatic vessel | 5 studies | 36% ± 8% | |
| monocyte | 5 studies | 36% ± 9% | |
| smooth muscle cell | 5 studies | 20% ± 3% | |
| type I pneumocyte | 5 studies | 28% ± 9% | |
| type II pneumocyte | 5 studies | 24% ± 7% | |
| CD16-positive, CD56-dim natural killer cell, human | 4 studies | 22% ± 5% | |
| neuron | 4 studies | 30% ± 13% | |
| cardiac muscle cell | 4 studies | 28% ± 2% | |
| lymphocyte | 4 studies | 39% ± 17% | |
| retina horizontal cell | 4 studies | 27% ± 13% | |
| retinal rod cell | 4 studies | 31% ± 5% | |
| club cell | 4 studies | 25% ± 8% | |
| pericyte | 4 studies | 27% ± 6% | |
| classical monocyte | 3 studies | 23% ± 4% | |
| GABAergic interneuron | 3 studies | 22% ± 5% | |
| retinal cone cell | 3 studies | 27% ± 8% | |
| gamma-delta T cell | 3 studies | 22% ± 4% | |
| hepatocyte | 3 studies | 33% ± 21% | |
| alveolar macrophage | 3 studies | 41% ± 11% | |
| respiratory goblet cell | 3 studies | 28% ± 12% | |
| basal cell | 3 studies | 34% ± 22% | |
| goblet cell | 3 studies | 42% ± 32% | |
| leukocyte | 3 studies | 43% ± 12% | |
| transit amplifying cell | 3 studies | 36% ± 26% | |
| granule cell | 3 studies | 21% ± 4% | |
| plasmacytoid dendritic cell | 3 studies | 22% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 4824.90 | 1445 / 1445 | 99% | 65.25 | 182 / 183 |
| prostate | 100% | 3251.21 | 245 / 245 | 99% | 55.59 | 497 / 502 |
| lung | 100% | 4070.00 | 578 / 578 | 99% | 45.43 | 1142 / 1155 |
| intestine | 100% | 3695.51 | 966 / 966 | 98% | 27.62 | 517 / 527 |
| stomach | 100% | 4532.25 | 359 / 359 | 98% | 30.93 | 280 / 286 |
| bladder | 100% | 3479.57 | 21 / 21 | 96% | 28.77 | 485 / 504 |
| pancreas | 99% | 1936.06 | 326 / 328 | 97% | 26.96 | 172 / 178 |
| thymus | 100% | 2571.51 | 652 / 653 | 94% | 19.54 | 569 / 605 |
| uterus | 100% | 3663.14 | 170 / 170 | 92% | 31.96 | 424 / 459 |
| kidney | 100% | 1772.10 | 89 / 89 | 90% | 19.55 | 807 / 901 |
| skin | 100% | 5277.74 | 1809 / 1809 | 89% | 21.11 | 422 / 472 |
| breast | 100% | 3338.86 | 459 / 459 | 86% | 20.56 | 964 / 1118 |
| ovary | 100% | 3204.73 | 180 / 180 | 86% | 11.53 | 370 / 430 |
| brain | 76% | 1004.07 | 1998 / 2642 | 83% | 9.18 | 583 / 705 |
| liver | 96% | 1278.81 | 218 / 226 | 61% | 7.89 | 246 / 406 |
| adrenal gland | 99% | 1657.17 | 255 / 258 | 57% | 5.77 | 131 / 230 |
| blood vessel | 100% | 3197.37 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 100% | 3555.55 | 241 / 241 | 0% | 0 | 0 / 0 |
| adipose | 100% | 3685.79 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| peripheral blood | 99% | 7690.43 | 919 / 929 | 0% | 0 | 0 / 0 |
| muscle | 98% | 1569.42 | 790 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 48.99 | 43 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 93% | 18.10 | 27 / 29 |
| heart | 92% | 1767.87 | 795 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 40% | 3.90 | 32 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0034220 | Biological process | monoatomic ion transmembrane transport |
| GO_0006811 | Biological process | monoatomic ion transport |
| GO_0045332 | Biological process | phospholipid translocation |
| GO_0015917 | Biological process | aminophospholipid transport |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0055037 | Cellular component | recycling endosome |
| GO_0031901 | Cellular component | early endosome membrane |
| GO_0035577 | Cellular component | azurophil granule membrane |
| GO_0055038 | Cellular component | recycling endosome membrane |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005637 | Cellular component | nuclear inner membrane |
| GO_1990531 | Cellular component | phospholipid-translocating ATPase complex |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0090556 | Molecular function | phosphatidylserine floppase activity |
| GO_0015075 | Molecular function | monoatomic ion transmembrane transporter activity |
| GO_0140326 | Molecular function | ATPase-coupled intramembrane lipid transporter activity |
| GO_0000287 | Molecular function | magnesium ion binding |
| GO_0090555 | Molecular function | phosphatidylethanolamine flippase activity |
| GO_0005524 | Molecular function | ATP binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0016887 | Molecular function | ATP hydrolysis activity |
| Gene name | ATP11B |
| Protein name | ATP11B protein ATPase phospholipid transporting 11B (putative) Phospholipid-transporting ATPase IF (EC 7.6.2.1) (ATPase IR) (ATPase class VI type 11B) (P4-ATPase flippase complex alpha subunit ATP11B) Truncated ATPase 11B protein Phospholipid-transporting ATPase (EC 7.6.2.1) Alternative protein ATP11B |
| Synonyms | KIAA0956 ATPIR ATPIF |
| Description | FUNCTION: Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids, phosphatidylserines (PS) and phosphatidylethanolamines (PE), from the outer to the inner leaflet of intracellular membranes . May contribute to the maintenance of membrane lipid asymmetry in endosome compartment . . |
| Accessions | A0A0C4DG94 H7C575 ENST00000484691.1 H7C4W6 Q8N4L6 ENST00000493826.1 L8E9M9 ENST00000498086.5 ENST00000482070.1 Q9Y2G3 H0Y854 ENST00000466758.5 H7C4E6 ENST00000491699.6 ENST00000323116.10 A5XEH5 H0Y8C7 |