UBXN8 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of UBXN8 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of UBXN8 at tissue level.

III. Associated gene sets

GO_0007338Biological processsingle fertilization
GO_0036503Biological processERAD pathway
GO_0005730Cellular componentnucleolus
GO_0000151Cellular componentubiquitin ligase complex
GO_0005654Cellular componentnucleoplasm
GO_0005783Cellular componentendoplasmic reticulum
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005634Cellular componentnucleus
GO_0030674Molecular functionprotein-macromolecule adaptor activity
GO_0005515Molecular functionprotein binding
GO_0043130Molecular functionubiquitin binding

IV. Literature review

[source]
Gene nameUBXN8
Protein nameUBX domain-containing protein 8 (Reproduction 8 protein) (Rep-8 protein) (UBX domain-containing protein 6)
UBX domain protein 8
SynonymsUBXD6
D8S2298E
REP8
DescriptionFUNCTION: Involved in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins, possibly by tethering VCP to the endoplasmic reticulum membrane. May play a role in reproduction. .

AccessionsENST00000341403.9
A0A087X0J2
ENST00000620074.5
ENST00000265616.10
A0A087WV67
ENST00000615729.4 [O00124-3]
A0A087WT23
A0A087WUA4
ENST00000380154.9
ENST00000518059.5
A0A087WZN0
A0A087WWA4
O00124
ENST00000522968.1