Insufficient scRNA-seq data for expression of UBXN8 at single-cell level.
Insufficient scRNA-seq data for expression of UBXN8 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 519.18 | 2637 / 2642 | 100% | 11.08 | 704 / 705 |
| prostate | 100% | 464.31 | 245 / 245 | 100% | 9.52 | 500 / 502 |
| pancreas | 100% | 440.62 | 328 / 328 | 99% | 6.31 | 177 / 178 |
| liver | 100% | 927.82 | 226 / 226 | 99% | 10.31 | 403 / 406 |
| thymus | 100% | 764.53 | 653 / 653 | 99% | 12.93 | 600 / 605 |
| skin | 100% | 578.91 | 1804 / 1809 | 99% | 14.25 | 468 / 472 |
| lung | 100% | 533.66 | 576 / 578 | 99% | 6.69 | 1143 / 1155 |
| uterus | 100% | 544.21 | 170 / 170 | 98% | 7.21 | 452 / 459 |
| ovary | 100% | 4254.99 | 180 / 180 | 98% | 7.08 | 423 / 430 |
| breast | 100% | 521.88 | 459 / 459 | 98% | 9.16 | 1098 / 1118 |
| adrenal gland | 100% | 1129.16 | 258 / 258 | 97% | 9.87 | 224 / 230 |
| bladder | 100% | 560.14 | 21 / 21 | 97% | 6.39 | 488 / 504 |
| kidney | 100% | 570.18 | 89 / 89 | 97% | 7.68 | 872 / 901 |
| stomach | 100% | 564.28 | 359 / 359 | 96% | 6.47 | 274 / 286 |
| intestine | 100% | 386.54 | 966 / 966 | 95% | 7.41 | 503 / 527 |
| esophagus | 100% | 389.36 | 1443 / 1445 | 95% | 5.16 | 173 / 183 |
| adipose | 100% | 617.66 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 5.89 | 29 / 29 |
| spleen | 100% | 941.10 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 2.58 | 1 / 1 |
| eye | 0% | 0 | 0 / 0 | 99% | 12.41 | 79 / 80 |
| blood vessel | 98% | 303.28 | 1309 / 1335 | 0% | 0 | 0 / 0 |
| heart | 94% | 222.71 | 812 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 93% | 4.86 | 42 / 45 |
| muscle | 87% | 192.67 | 695 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 46% | 150.65 | 431 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007338 | Biological process | single fertilization |
| GO_0036503 | Biological process | ERAD pathway |
| GO_0005730 | Cellular component | nucleolus |
| GO_0000151 | Cellular component | ubiquitin ligase complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0005634 | Cellular component | nucleus |
| GO_0030674 | Molecular function | protein-macromolecule adaptor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0043130 | Molecular function | ubiquitin binding |
| Gene name | UBXN8 |
| Protein name | UBX domain-containing protein 8 (Reproduction 8 protein) (Rep-8 protein) (UBX domain-containing protein 6) UBX domain protein 8 |
| Synonyms | UBXD6 D8S2298E REP8 |
| Description | FUNCTION: Involved in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins, possibly by tethering VCP to the endoplasmic reticulum membrane. May play a role in reproduction. . |
| Accessions | ENST00000341403.9 A0A087X0J2 ENST00000620074.5 ENST00000265616.10 A0A087WV67 ENST00000615729.4 [O00124-3] A0A087WT23 A0A087WUA4 ENST00000380154.9 ENST00000518059.5 A0A087WZN0 A0A087WWA4 O00124 ENST00000522968.1 |