Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 7 studies | 27% ± 9% | |
| endothelial cell | 6 studies | 28% ± 9% | |
| secretory cell | 5 studies | 23% ± 8% | |
| goblet cell | 5 studies | 21% ± 4% | |
| glutamatergic neuron | 4 studies | 33% ± 14% | |
| GABAergic neuron | 4 studies | 31% ± 11% | |
| respiratory goblet cell | 3 studies | 23% ± 6% | |
| squamous epithelial cell | 3 studies | 40% ± 25% | |
| basal cell | 3 studies | 30% ± 9% | |
| interneuron | 3 studies | 35% ± 19% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 24% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| intestine | 100% | 4618.52 | 965 / 966 | 100% | 52.77 | 527 / 527 |
| uterus | 100% | 2895.09 | 170 / 170 | 100% | 39.95 | 457 / 459 |
| ovary | 99% | 2037.98 | 179 / 180 | 100% | 32.91 | 430 / 430 |
| stomach | 100% | 2978.76 | 358 / 359 | 100% | 43.37 | 285 / 286 |
| bladder | 100% | 3330.95 | 21 / 21 | 99% | 51.92 | 500 / 504 |
| esophagus | 99% | 3088.54 | 1432 / 1445 | 100% | 38.95 | 183 / 183 |
| skin | 100% | 2360.78 | 1806 / 1809 | 97% | 17.81 | 458 / 472 |
| lung | 98% | 1761.13 | 566 / 578 | 99% | 31.22 | 1140 / 1155 |
| brain | 96% | 6213.15 | 2537 / 2642 | 100% | 20.91 | 702 / 705 |
| thymus | 96% | 1396.18 | 630 / 653 | 98% | 18.80 | 590 / 605 |
| breast | 100% | 2770.93 | 458 / 459 | 94% | 13.87 | 1053 / 1118 |
| kidney | 96% | 1282.22 | 85 / 89 | 96% | 14.95 | 862 / 901 |
| pancreas | 78% | 818.73 | 256 / 328 | 99% | 93.83 | 176 / 178 |
| prostate | 99% | 2002.82 | 243 / 245 | 75% | 7.76 | 374 / 502 |
| adrenal gland | 82% | 787.25 | 212 / 258 | 89% | 27.04 | 204 / 230 |
| spleen | 100% | 2855.16 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 30.77 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 107.82 | 1 / 1 |
| adipose | 100% | 2798.24 | 1202 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 21.46 | 28 / 29 |
| heart | 96% | 1992.89 | 824 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 95% | 1715.52 | 1263 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 75% | 1344.89 | 699 / 929 | 0% | 0 | 0 / 0 |
| muscle | 57% | 562.23 | 461 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 56% | 5.09 | 45 / 80 |
| liver | 4% | 38.76 | 10 / 226 | 26% | 5.09 | 106 / 406 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006654 | Biological process | phosphatidic acid biosynthetic process |
| GO_0006644 | Biological process | phospholipid metabolic process |
| GO_0036148 | Biological process | phosphatidylglycerol acyl-chain remodeling |
| GO_0036150 | Biological process | phosphatidylserine acyl-chain remodeling |
| GO_0036151 | Biological process | phosphatidylcholine acyl-chain remodeling |
| GO_0036152 | Biological process | phosphatidylethanolamine acyl-chain remodeling |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0016020 | Cellular component | membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0047144 | Molecular function | 2-acylglycerol-3-phosphate O-acyltransferase activity |
| GO_0047192 | Molecular function | 1-alkylglycerophosphocholine O-acetyltransferase activity |
| GO_0003841 | Molecular function | 1-acylglycerol-3-phosphate O-acyltransferase activity |
| GO_0071617 | Molecular function | lysophospholipid acyltransferase activity |
| GO_0106263 | Molecular function | 1-acylglycerophosphoserine O-acyltransferase activity |
| GO_0047184 | Molecular function | 1-acylglycerophosphocholine O-acyltransferase activity |
| GO_0042171 | Molecular function | lysophosphatidic acid acyltransferase activity |
| GO_0047166 | Molecular function | 1-alkenylglycerophosphoethanolamine O-acyltransferase activity |
| GO_0106262 | Molecular function | 1-acylglycerophosphoethanolamine O-acyltransferase activity |
| Gene name | LPCAT4 |
| Protein name | LPCAT4 protein Lysophospholipid acyltransferase LPCAT4 (1-acylglycerol-3-phosphate O-acyltransferase 7) (1-AGP acyltransferase 7) (1-AGPAT 7) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n6) (1-alkenylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.121) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acyltransferase-like 3) (Lysophosphatidylcholine acyltransferase 4) (Lysophosphatidylethanolamine acyltransferase 2) (EC 2.3.1.n7) (Plasmalogen synthase) Lysophosphatidylcholine acyltransferase 4 |
| Synonyms | LPEAT2 AYTL3 AGPAT7 |
| Description | FUNCTION: Displays acyl-CoA-dependent lysophospholipid acyltransferase activity with a subset of lysophospholipids as substrates; converts lysophosphatidylethanolamine to phosphatidylethanolamine, lysophosphatidylcholine to phosphatidycholine, 1-alkenyl-lysophatidylethanolamine to 1-alkenyl-phosphatidylethanolamine, lysophosphatidylglycerol and alkyl-lysophosphatidylcholine to phosphatidylglycerol and alkyl-phosphatidylcholine, respectively. In contrast, has no lysophosphatidylinositol, glycerol-3-phosphate, diacylglycerol or lysophosphatidic acid acyltransferase activity. Prefers long chain acyl-CoAs (C16, C18) as acyl donors. . |
| Accessions | ENST00000314891.11 Q643R3 ENST00000709501.1 B7ZM32 ENST00000567507.1 H3BMK4 |
