MIA2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0035459Biological processvesicle cargo loading
GO_0006888Biological processendoplasmic reticulum to Golgi vesicle-mediated transport
GO_0009306Biological processprotein secretion
GO_0005783Cellular componentendoplasmic reticulum
GO_0070971Cellular componentendoplasmic reticulum exit site
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMIA2
Protein nameCTAGE5 protein
MIA SH3 domain ER export factor 2
MIA2 protein
Melanoma inhibitory activity protein 2 (MIA protein 2) (CTAGE family member 5 ER export factor) (Cutaneous T-cell lymphoma-associated antigen 5) (Meningioma-expressed antigen 6/11)
SynonymsMGEA6
CTAGE5
MEA11
MEA6
MGEA11
DescriptionFUNCTION: Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum . Plays a role in the secretion of lipoproteins, pre-chylomicrons and pre-VLDLs, by participating in their export from the endoplasmic reticulum . Thereby, may play a role in cholesterol and triglyceride homeostasis (By similarity). Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers and recruiting PREB/SEC12 at the endoplasmic reticulum exit sites . .

AccessionsENST00000553728.1
Q96PC5
Q05BM1
ENST00000341502.9 [Q96PC5-10]
ENST00000554392.5
Q4G155
ENST00000348007.7 [Q96PC5-8]
ENST00000341749.7 [Q96PC5-14]
ENST00000557148.5
ENST00000557038.5 [Q96PC5-11]
ENST00000555716.5
G3V3C4
ENST00000280082.4 [Q96PC5-2]
ENST00000396165.8 [Q96PC5-9]
ENST00000640607.2 [Q96PC5-3]
ENST00000553352.1 [Q96PC5-9]
ENST00000556148.5 [Q96PC5-13]
G3V4M1
ENST00000396158.6 [Q96PC5-12]
ENST00000280083.7 [Q96PC5-7]
Q6PIE7
G3V599
G3V5K6