TXNDC12 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	18 studies	26% ± 10%	Explore
macrophage	13 studies	23% ± 8%	Explore
natural killer cell	12 studies	20% ± 4%	Explore
fibroblast	11 studies	22% ± 9%	Explore
CD8-positive, alpha-beta T cell	10 studies	18% ± 3%	Explore
endothelial cell of lymphatic vessel	9 studies	23% ± 7%	Explore
non-classical monocyte	9 studies	25% ± 12%	Explore
CD4-positive, alpha-beta T cell	9 studies	19% ± 2%	Explore
regulatory T cell	9 studies	20% ± 4%	Explore
gamma-delta T cell	9 studies	20% ± 7%	Explore
plasma cell	7 studies	26% ± 11%	Explore
CD16-positive, CD56-dim natural killer cell, human	7 studies	19% ± 2%	Explore
classical monocyte	7 studies	24% ± 9%	Explore
epithelial cell	7 studies	40% ± 19%	Explore
CD16-negative, CD56-bright natural killer cell, human	6 studies	18% ± 3%	Explore
capillary endothelial cell	6 studies	21% ± 2%	Explore
endothelial cell of artery	6 studies	18% ± 2%	Explore
endothelial cell of vascular tree	6 studies	20% ± 3%	Explore
B cell	6 studies	21% ± 7%	Explore
ciliated cell	6 studies	30% ± 11%	Explore
plasmacytoid dendritic cell	6 studies	23% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	17% ± 1%	Explore
conventional dendritic cell	5 studies	32% ± 11%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	19% ± 2%	Explore
connective tissue cell	5 studies	22% ± 4%	Explore
monocyte	5 studies	22% ± 7%	Explore
memory B cell	5 studies	16% ± 1%	Explore
mucosal invariant T cell	5 studies	18% ± 2%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	4 studies	17% ± 2%	Explore
mature NK T cell	4 studies	17% ± 2%	Explore
T cell	4 studies	18% ± 3%	Explore
pericyte	4 studies	20% ± 4%	Explore
myeloid cell	4 studies	28% ± 9%	Explore
vein endothelial cell	4 studies	21% ± 5%	Explore
glutamatergic neuron	4 studies	28% ± 12%	Explore
oligodendrocyte precursor cell	4 studies	20% ± 4%	Explore
enteroendocrine cell	4 studies	24% ± 12%	Explore
basal cell	4 studies	32% ± 14%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	20% ± 5%	Explore
plasmablast	3 studies	51% ± 15%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	19% ± 3%	Explore
pancreatic A cell	3 studies	33% ± 8%	Explore
naive B cell	3 studies	18% ± 2%	Explore
exhausted T cell	3 studies	20% ± 5%	Explore
hematopoietic precursor cell	3 studies	30% ± 5%	Explore
neural crest cell	3 studies	18% ± 3%	Explore
progenitor cell	3 studies	20% ± 3%	Explore
pro-B cell	3 studies	23% ± 2%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	17% ± 2%	Explore
GABAergic neuron	3 studies	25% ± 7%	Explore
dendritic cell	3 studies	45% ± 9%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	20% ± 5%	Explore
goblet cell	3 studies	28% ± 11%	Explore
intestinal crypt stem cell	3 studies	23% ± 1%	Explore
double negative thymocyte	3 studies	23% ± 8%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	8 studies	21% ± 5%	Explore
lung	7 studies	24% ± 6%	Explore
brain	6 studies	21% ± 6%	Explore
pancreas	3 studies	32% ± 9%	Explore
liver	3 studies	21% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
stomach	100%	2222.53	359 / 359	99%	8.34	284 / 286
ovary	100%	2756.58	180 / 180	98%	8.18	423 / 430
esophagus	100%	1805.92	1444 / 1445	98%	5.69	180 / 183
intestine	100%	2292.34	966 / 966	98%	9.00	516 / 527
lung	100%	2810.48	578 / 578	98%	6.76	1127 / 1155
brain	100%	1964.92	2639 / 2642	96%	6.22	679 / 705
pancreas	100%	2311.59	328 / 328	96%	5.63	171 / 178
skin	100%	2966.82	1809 / 1809	94%	6.73	445 / 472
breast	100%	2879.41	459 / 459	94%	5.51	1050 / 1118
prostate	100%	2206.27	245 / 245	94%	5.59	471 / 502
bladder	100%	2132.57	21 / 21	93%	7.60	471 / 504
uterus	100%	2262.18	170 / 170	93%	6.38	425 / 459
thymus	100%	2760.81	653 / 653	88%	4.73	535 / 605
kidney	100%	2224.76	89 / 89	85%	4.91	766 / 901
liver	100%	1814.08	226 / 226	82%	4.12	332 / 406
adrenal gland	100%	2808.90	258 / 258	79%	4.43	181 / 230
adipose	100%	2940.48	1204 / 1204	0%	0	0 / 0
spleen	100%	2677.25	241 / 241	0%	0	0 / 0
blood vessel	100%	2167.00	1332 / 1335	0%	0	0 / 0
peripheral blood	99%	3031.84	923 / 929	0%	0	0 / 0
heart	98%	1550.48	848 / 861	0%	0	0 / 0
muscle	98%	1045.33	788 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	96%	6.15	43 / 45
eye	0%	0	0 / 0	91%	4.83	73 / 80
lymph node	0%	0	0 / 0	72%	4.37	21 / 29
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_1902236	Biological process	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO_0005788	Cellular component	endoplasmic reticulum lumen
GO_0005783	Cellular component	endoplasmic reticulum
GO_0019153	Molecular function	protein-disulfide reductase (glutathione) activity
GO_0015035	Molecular function	protein-disulfide reductase activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	TXNDC12
Protein name	Thioredoxin domain-containing protein 12 (EC 1.8.4.2) (Endoplasmic reticulum resident protein 18) (ER protein 18) (ERp18) (Endoplasmic reticulum resident protein 19) (ER protein 19) (ERp19) (Thioredoxin-like protein p19) (hTLP19) Thioredoxin domain containing 12
Synonyms	TLP19 UNQ713/PRO1376
Description	FUNCTION: Protein-disulfide reductase of the endoplasmic reticulum that promotes disulfide bond formation in client proteins through its thiol-disulfide oxidase activity. .
Accessions	O95881 ENST00000610127.2 ENST00000371626.9 ENST00000472624.5 V9GY50 V9GYV4

TXNDC12 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review