PRKCSH | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	18 studies	22% ± 5%	Explore
endothelial cell	15 studies	24% ± 9%	Explore
fibroblast	15 studies	29% ± 9%	Explore
CD8-positive, alpha-beta T cell	15 studies	19% ± 4%	Explore
regulatory T cell	14 studies	20% ± 3%	Explore
B cell	13 studies	22% ± 4%	Explore
CD4-positive, alpha-beta T cell	13 studies	19% ± 4%	Explore
classical monocyte	13 studies	25% ± 10%	Explore
plasma cell	11 studies	31% ± 10%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	22% ± 4%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	22% ± 7%	Explore
macrophage	11 studies	21% ± 7%	Explore
gamma-delta T cell	11 studies	22% ± 8%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	25% ± 6%	Explore
epithelial cell	10 studies	38% ± 21%	Explore
pericyte	10 studies	23% ± 5%	Explore
memory B cell	10 studies	22% ± 6%	Explore
naive B cell	10 studies	22% ± 5%	Explore
basal cell	9 studies	25% ± 13%	Explore
non-classical monocyte	9 studies	25% ± 11%	Explore
connective tissue cell	9 studies	30% ± 7%	Explore
abnormal cell	9 studies	24% ± 9%	Explore
oligodendrocyte	9 studies	24% ± 7%	Explore
mucosal invariant T cell	9 studies	22% ± 4%	Explore
plasmacytoid dendritic cell	9 studies	26% ± 3%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	22% ± 6%	Explore
conventional dendritic cell	8 studies	30% ± 15%	Explore
myofibroblast cell	8 studies	24% ± 6%	Explore
ciliated cell	7 studies	29% ± 11%	Explore
mature NK T cell	7 studies	20% ± 4%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	7 studies	21% ± 3%	Explore
T cell	7 studies	22% ± 5%	Explore
goblet cell	7 studies	23% ± 9%	Explore
smooth muscle cell	7 studies	20% ± 2%	Explore
plasmablast	6 studies	46% ± 21%	Explore
hematopoietic precursor cell	5 studies	37% ± 14%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	22% ± 2%	Explore
progenitor cell	5 studies	26% ± 6%	Explore
enterocyte	5 studies	21% ± 2%	Explore
mesothelial cell	5 studies	29% ± 16%	Explore
hematopoietic stem cell	5 studies	31% ± 9%	Explore
myeloid cell	5 studies	31% ± 13%	Explore
monocyte	5 studies	22% ± 5%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	26% ± 7%	Explore
exhausted T cell	4 studies	21% ± 5%	Explore
neuron	4 studies	28% ± 12%	Explore
endothelial cell of lymphatic vessel	4 studies	25% ± 7%	Explore
T follicular helper cell	4 studies	17% ± 1%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	19% ± 3%	Explore
endothelial cell of vascular tree	4 studies	20% ± 2%	Explore
innate lymphoid cell	4 studies	18% ± 2%	Explore
dendritic cell	4 studies	37% ± 15%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	21% ± 7%	Explore
enteroendocrine cell	4 studies	25% ± 10%	Explore
secretory cell	3 studies	23% ± 4%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	29% ± 6%	Explore
endothelial cell of artery	3 studies	18% ± 2%	Explore
intestinal crypt stem cell	3 studies	20% ± 3%	Explore
neural crest cell	3 studies	22% ± 1%	Explore
vein endothelial cell	3 studies	23% ± 7%	Explore
transit amplifying cell	3 studies	20% ± 1%	Explore
glutamatergic neuron	3 studies	31% ± 12%	Explore
common myeloid progenitor	3 studies	34% ± 14%	Explore
type I pneumocyte	3 studies	30% ± 9%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	24% ± 3%	Explore
granulocyte monocyte progenitor cell	3 studies	30% ± 8%	Explore
group 3 innate lymphoid cell	3 studies	24% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	18% ± 3%	Explore
double negative thymocyte	3 studies	28% ± 7%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	12 studies	24% ± 5%	Explore
intestine	8 studies	22% ± 10%	Explore
lung	6 studies	27% ± 6%	Explore
brain	5 studies	25% ± 7%	Explore
kidney	4 studies	20% ± 3%	Explore
placenta	3 studies	31% ± 4%	Explore
bone marrow	3 studies	25% ± 11%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	9359.55	1445 / 1445	100%	202.62	183 / 183
liver	100%	9704.44	226 / 226	100%	204.98	406 / 406
ovary	100%	18768.58	180 / 180	100%	329.21	430 / 430
skin	100%	15110.37	1809 / 1809	100%	329.20	472 / 472
thymus	100%	14557.71	653 / 653	100%	240.62	605 / 605
uterus	100%	14242.18	170 / 170	100%	256.91	459 / 459
brain	100%	8370.47	2639 / 2642	100%	176.30	705 / 705
pancreas	100%	10537.71	328 / 328	99%	190.27	177 / 178
intestine	100%	12022.45	966 / 966	99%	225.55	524 / 527
stomach	100%	9960.40	359 / 359	99%	207.56	284 / 286
kidney	100%	10998.89	89 / 89	99%	199.32	894 / 901
prostate	100%	12789.24	245 / 245	99%	290.25	498 / 502
adrenal gland	100%	11226.19	258 / 258	99%	199.66	228 / 230
breast	100%	12486.74	459 / 459	99%	205.46	1103 / 1118
bladder	100%	11115.33	21 / 21	99%	232.07	497 / 504
lung	100%	11137.62	578 / 578	98%	199.79	1137 / 1155
adipose	100%	11592.43	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	408.27	80 / 80
lymph node	0%	0	0 / 0	100%	191.66	29 / 29
spleen	100%	12197.70	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	213.73	45 / 45
ureter	0%	0	0 / 0	100%	158.81	1 / 1
blood vessel	100%	9724.78	1334 / 1335	0%	0	0 / 0
peripheral blood	99%	10915.00	919 / 929	0%	0	0 / 0
muscle	99%	4365.03	793 / 803	0%	0	0 / 0
heart	98%	6302.48	847 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0035556	Biological process	intracellular signal transduction
GO_0001889	Biological process	liver development
GO_0006491	Biological process	N-glycan processing
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0005788	Cellular component	endoplasmic reticulum lumen
GO_0005783	Cellular component	endoplasmic reticulum
GO_0017177	Cellular component	glucosidase II complex
GO_0005080	Molecular function	protein kinase C binding
GO_0005509	Molecular function	calcium ion binding
GO_0051219	Molecular function	phosphoprotein binding
GO_0005515	Molecular function	protein binding
GO_0044325	Molecular function	transmembrane transporter binding

IV. Literature review

[source]

Gene name	PRKCSH
Protein name	Glucosidase 2 subunit beta (80K-H protein) (Glucosidase II subunit beta) (Protein kinase C substrate 60.1 kDa protein heavy chain) (PKCSH) Glucosidase 2 subunit beta Protein kinase C substrate 80K-H isoform 4 Protein kinase C substrate 80K-H isoform 2 PRKCSH protein Protein kinase C substrate 80K-H Protein kinase C substrate 80K-H isoform 1
Synonyms	G19P1
Description	FUNCTION: Regulatory subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins . Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia (By similarity). .
Accessions	A0A0C4DGP4 ENST00000591462.6 [P14314-2] K7EIP3 K7ELL7 A0A0S2Z4A0 ENST00000676823.1 A0A0S2Z4D8 ENST00000592741.5 ENST00000593101.5 ENST00000586486.1 ENST00000677123.1 P14314 A0A7I2V2T6 K7EPW7 ENST00000587509.5 ENST00000587327.5 [P14314-2] ENST00000589838.5 [P14314-1] A2VCQ4 K7EJ70 ENST00000588269.1 K7EL27 A0A0S2Z4W7 ENST00000591946.5 K7EKX1 ENST00000589126.5

PRKCSH report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review