NT5C3A | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	16 studies	23% ± 5%	Explore
naive B cell	15 studies	24% ± 6%	Explore
endothelial cell	14 studies	23% ± 7%	Explore
regulatory T cell	13 studies	21% ± 4%	Explore
platelet	10 studies	47% ± 13%	Explore
natural killer cell	10 studies	20% ± 4%	Explore
memory B cell	10 studies	20% ± 2%	Explore
ciliated cell	8 studies	24% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	7 studies	18% ± 1%	Explore
CD16-positive, CD56-dim natural killer cell, human	7 studies	18% ± 2%	Explore
CD8-positive, alpha-beta T cell	7 studies	20% ± 4%	Explore
fibroblast	7 studies	19% ± 3%	Explore
gamma-delta T cell	7 studies	20% ± 6%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	18% ± 1%	Explore
basal cell	6 studies	25% ± 7%	Explore
non-classical monocyte	5 studies	23% ± 9%	Explore
CD4-positive, alpha-beta T cell	5 studies	21% ± 4%	Explore
epithelial cell	5 studies	39% ± 13%	Explore
GABAergic neuron	5 studies	40% ± 12%	Explore
astrocyte	5 studies	26% ± 4%	Explore
oligodendrocyte	5 studies	22% ± 3%	Explore
T cell	5 studies	19% ± 4%	Explore
interneuron	5 studies	32% ± 16%	Explore
monocyte	4 studies	18% ± 2%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	16% ± 1%	Explore
neuron	4 studies	29% ± 8%	Explore
megakaryocyte	4 studies	56% ± 15%	Explore
retinal cone cell	4 studies	30% ± 14%	Explore
macrophage	4 studies	21% ± 3%	Explore
type I pneumocyte	4 studies	16% ± 1%	Explore
glutamatergic neuron	4 studies	53% ± 11%	Explore
oligodendrocyte precursor cell	4 studies	31% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	19% ± 3%	Explore
goblet cell	4 studies	23% ± 4%	Explore
endothelial cell of lymphatic vessel	4 studies	20% ± 3%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	22% ± 8%	Explore
hematopoietic stem cell	4 studies	33% ± 17%	Explore
mucosal invariant T cell	4 studies	17% ± 0%	Explore
plasmacytoid dendritic cell	4 studies	21% ± 6%	Explore
hematopoietic precursor cell	3 studies	31% ± 15%	Explore
plasmablast	3 studies	42% ± 15%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	17% ± 1%	Explore
classical monocyte	3 studies	22% ± 5%	Explore
microglial cell	3 studies	20% ± 3%	Explore
immature B cell	3 studies	23% ± 4%	Explore
lymphocyte	3 studies	22% ± 4%	Explore
innate lymphoid cell	3 studies	16% ± 1%	Explore
erythrocyte	3 studies	27% ± 12%	Explore
abnormal cell	3 studies	27% ± 2%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	42% ± 24%	Explore
enteroendocrine cell	3 studies	31% ± 9%	Explore
transit amplifying cell	3 studies	26% ± 14%	Explore
brush cell	3 studies	28% ± 12%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	20% ± 4%	Explore
mature NK T cell	3 studies	17% ± 1%	Explore
double negative thymocyte	3 studies	22% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	9 studies	19% ± 4%	Explore
brain	6 studies	35% ± 15%	Explore
eye	3 studies	22% ± 1%	Explore
lung	3 studies	22% ± 5%	Explore
intestine	3 studies	20% ± 5%	Explore
liver	3 studies	30% ± 10%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	1342.12	577 / 578	100%	31.30	1154 / 1155
pancreas	100%	1090.97	327 / 328	100%	35.64	178 / 178
stomach	100%	855.96	359 / 359	100%	41.54	285 / 286
brain	100%	856.97	2632 / 2642	100%	27.28	705 / 705
uterus	100%	1337.19	170 / 170	100%	30.19	457 / 459
breast	100%	1335.92	459 / 459	100%	33.52	1113 / 1118
thymus	100%	1135.88	653 / 653	100%	29.31	602 / 605
esophagus	100%	1001.48	1445 / 1445	99%	43.51	182 / 183
bladder	100%	1073.43	21 / 21	99%	33.96	501 / 504
ovary	100%	1228.86	180 / 180	99%	25.01	427 / 430
prostate	100%	1109.11	245 / 245	99%	19.71	498 / 502
kidney	100%	1060.34	89 / 89	99%	29.43	891 / 901
skin	100%	1419.40	1809 / 1809	99%	38.38	466 / 472
intestine	100%	1535.24	966 / 966	98%	45.49	518 / 527
adrenal gland	100%	1217.43	258 / 258	97%	16.62	223 / 230
liver	99%	575.42	224 / 226	82%	12.79	333 / 406
adipose	100%	1289.31	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	32.91	29 / 29
muscle	100%	2666.19	803 / 803	0%	0	0 / 0
spleen	100%	1693.94	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	23.82	45 / 45
ureter	0%	0	0 / 0	100%	20.70	1 / 1
blood vessel	100%	840.73	1332 / 1335	0%	0	0 / 0
peripheral blood	98%	2387.88	915 / 929	0%	0	0 / 0
heart	98%	696.00	842 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	89%	13.33	71 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0051607	Biological process	defense response to virus
GO_0006213	Biological process	pyrimidine nucleoside metabolic process
GO_0009117	Biological process	nucleotide metabolic process
GO_0016604	Cellular component	nuclear body
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005783	Cellular component	endoplasmic reticulum
GO_0005737	Cellular component	cytoplasm
GO_0000287	Molecular function	magnesium ion binding
GO_0106411	Molecular function	XMP 5'-nucleosidase activity
GO_0000215	Molecular function	tRNA 2'-phosphotransferase activity
GO_0005515	Molecular function	protein binding
GO_0008253	Molecular function	5'-nucleotidase activity
GO_0000166	Molecular function	nucleotide binding

IV. Literature review

[source]

Gene name	NT5C3A
Protein name	7-methylguanosine nucleotidase (EC 3.1.3.91) Cytosolic 5'-nucleotidase 3A (EC 3.1.3.5) (7-methylguanosine phosphate-specific 5'-nucleotidase) (7-methylguanosine nucleotidase) (EC 3.1.3.91) (Cytosolic 5'-nucleotidase 3) (Cytosolic 5'-nucleotidase III) (cN-III) (Pyrimidine 5'-nucleotidase 1) (P5'N-1) (P5N-1) (PN-I) (Uridine 5'-monophosphate hydrolase 1) (p36) 5'-nucleotidase (EC 3.1.3.5) 5'-nucleotidase, cytosolic IIIA
Synonyms	UMPH1 NT5C3 P5N1 HSPC233
Description	FUNCTION: Nucleotidase which shows specific activity towards cytidine monophosphate (CMP) and 7-methylguanosine monophosphate (m(7)GMP) . CMP seems to be the preferred substrate . .
Accessions	X6RM59 B9A035 ENST00000409787.4 ENST00000610140.7 ENST00000409467.6 [Q9H0P0-3] Q9H0P0 C9K084 ENST00000449201.5 F8WDR0 ENST00000456458.5 ENST00000643244.1 [Q9H0P0-1]

NT5C3A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review