MAGT1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0015693Biological processmagnesium ion transport
GO_0050890Biological processcognition
GO_0018279Biological processprotein N-linked glycosylation via asparagine
GO_0006487Biological processprotein N-linked glycosylation
GO_1903830Biological processmagnesium ion transmembrane transport
GO_0055085Biological processtransmembrane transport
GO_0008250Cellular componentoligosaccharyltransferase complex
GO_0035577Cellular componentazurophil granule membrane
GO_0005783Cellular componentendoplasmic reticulum
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0015095Molecular functionmagnesium ion transmembrane transporter activity

IV. Literature review

[source]
Gene nameMAGT1
Protein nameMagnesium transporter protein 1 (MagT1) (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1) (Oligosaccharyl transferase subunit MAGT1) (Implantation-associated protein) (IAP)
Magnesium transporter protein 1 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1)
SynonymsUNQ628/PRO1244
IAG2
PSEC0084
DescriptionFUNCTION: Accessory component of the STT3B-containing form of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains . Involved in N-glycosylation of STT3B-dependent substrates . Specifically required for the glycosylation of a subset of acceptor sites that are near cysteine residues; in this function seems to act redundantly with TUSC3. In its oxidized form proposed to form transient mixed disulfides with a glycoprotein substrate to facilitate access of STT3B to the unmodified acceptor site. Has also oxidoreductase-independent functions in the STT3B-containing OST complex possibly involving substrate recognition. .; FUNCTION: May be involved in Mg(2+) transport in epithelial cells. .

AccessionsENST00000689137.1
ENST00000358075.11 [Q9H0U3-1]
A0A8I5KYH1
ENST00000689519.1
Q9H0U3
ENST00000691172.1
A0A8I5QJM4
ENST00000692161.1
ENST00000373336.3 [Q9H0U3-2]
ENST00000688650.1
A0A8I5QJJ8
ENST00000685015.1
ENST00000618282.5 [Q9H0U3-1]
A0A8I5KUC4
A0A8I5QKX7
A0A087WU53
ENST00000691993.1
A0A8I5KY62
ENST00000358075
ENST00000685353.1