TFPI report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030195Biological processnegative regulation of blood coagulation
GO_0071383Biological processcellular response to steroid hormone stimulus
GO_0007596Biological processblood coagulation
GO_0005615Cellular componentextracellular space
GO_0009986Cellular componentcell surface
GO_0098552Cellular componentside of membrane
GO_0005783Cellular componentendoplasmic reticulum
GO_0005576Cellular componentextracellular region
GO_0005886Cellular componentplasma membrane
GO_0005901Cellular componentcaveola
GO_0004866Molecular functionendopeptidase inhibitor activity
GO_0004867Molecular functionserine-type endopeptidase inhibitor activity

IV. Literature review

[source]
Gene nameTFPI
Protein nameTissue factor pathway inhibitor (TFPI) (Extrinsic pathway inhibitor) (EPI) (Lipoprotein-associated coagulation inhibitor) (LACI)
Tissue factor pathway inhibitor
SynonymsLACI
TFPI1
DescriptionFUNCTION: Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.

AccessionsENST00000437725.5
ENST00000339091.8 [P10646-2]
P10646
C9JT76
C9J103
C9JKV3
C9JP39
ENST00000409676.5 [P10646-2]
ENST00000420747.1
ENST00000421427.5
ENST00000453013.5
C9JQ14
ENST00000435414.5
ENST00000392365.5 [P10646-1]
ENST00000417013.5
ENST00000233156.9 [P10646-1]