GPAT4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006654Biological processphosphatidic acid biosynthetic process
GO_0006656Biological processphosphatidylcholine biosynthetic process
GO_0002071Biological processglandular epithelial cell maturation
GO_0019432Biological processtriglyceride biosynthetic process
GO_0046339Biological processdiacylglycerol metabolic process
GO_0007595Biological processlactation
GO_0008610Biological processlipid biosynthetic process
GO_0040014Biological processregulation of multicellular organism growth
GO_0006631Biological processfatty acid metabolic process
GO_0006637Biological processacyl-CoA metabolic process
GO_0016024Biological processCDP-diacylglycerol biosynthetic process
GO_0005783Cellular componentendoplasmic reticulum
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0004366Molecular functionglycerol-3-phosphate O-acyltransferase activity
GO_0003841Molecular function1-acylglycerol-3-phosphate O-acyltransferase activity
GO_0102420Molecular functionsn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity

IV. Literature review

[source]
Gene nameGPAT4
Protein nameGlycerol-3-phosphate acyltransferase 4
Glycerol-3-phosphate acyltransferase 4 (EC 2.3.1.15) (1-acylglycerol-3-phosphate O-acyltransferase 6) (1-AGP acyltransferase 6) (1-AGPAT 6) (Acyl-CoA:glycerol-3-phosphate acyltransferase 4) (Lysophosphatidic acid acyltransferase zeta) (LPAAT-zeta) (Testis spermatogenesis apoptosis-related protein 7) (TSARG7)
SynonymsTSARG7
AGPAT6
UNQ551/PRO1108
DescriptionFUNCTION: Converts glycerol-3-phosphate to 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) by incorporating an acyl moiety at the sn-1 position of the glycerol backbone . Active against both saturated and unsaturated long-chain fatty acyl-CoAs . Protects cells against lipotoxicity . .

AccessionsENST00000521806.5
Q86UL3
ENST00000520223.1
ENST00000519853.5
E5RGW3
E5RIA1
E5RHA6
ENST00000396987.7