LMAN1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	38 studies	33% ± 16%	Explore
endothelial cell	32 studies	26% ± 9%	Explore
plasma cell	25 studies	53% ± 21%	Explore
pericyte	22 studies	26% ± 13%	Explore
ciliated cell	18 studies	40% ± 17%	Explore
regulatory T cell	17 studies	27% ± 10%	Explore
macrophage	16 studies	22% ± 6%	Explore
epithelial cell	16 studies	38% ± 21%	Explore
connective tissue cell	16 studies	32% ± 14%	Explore
natural killer cell	15 studies	24% ± 7%	Explore
CD8-positive, alpha-beta T cell	15 studies	27% ± 9%	Explore
smooth muscle cell	14 studies	22% ± 4%	Explore
plasmacytoid dendritic cell	14 studies	36% ± 9%	Explore
basal cell	14 studies	35% ± 12%	Explore
endothelial cell of lymphatic vessel	13 studies	25% ± 8%	Explore
plasmablast	12 studies	65% ± 26%	Explore
secretory cell	11 studies	33% ± 12%	Explore
CD4-positive, alpha-beta T cell	11 studies	28% ± 10%	Explore
capillary endothelial cell	11 studies	21% ± 5%	Explore
vein endothelial cell	11 studies	22% ± 5%	Explore
gamma-delta T cell	11 studies	26% ± 10%	Explore
B cell	10 studies	20% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	22% ± 4%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	22% ± 4%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	20% ± 4%	Explore
mature NK T cell	10 studies	21% ± 4%	Explore
myofibroblast cell	10 studies	28% ± 9%	Explore
endothelial cell of artery	10 studies	21% ± 3%	Explore
mesothelial cell	10 studies	33% ± 15%	Explore
T cell	9 studies	20% ± 3%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	24% ± 5%	Explore
goblet cell	9 studies	34% ± 17%	Explore
IgG plasma cell	9 studies	45% ± 13%	Explore
mucosal invariant T cell	9 studies	27% ± 4%	Explore
type II pneumocyte	8 studies	29% ± 15%	Explore
club cell	8 studies	30% ± 13%	Explore
abnormal cell	8 studies	34% ± 13%	Explore
IgA plasma cell	8 studies	45% ± 18%	Explore
endothelial cell of vascular tree	8 studies	25% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	26% ± 9%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	7 studies	20% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	23% ± 4%	Explore
type I pneumocyte	6 studies	32% ± 10%	Explore
hematopoietic precursor cell	6 studies	25% ± 9%	Explore
respiratory goblet cell	6 studies	30% ± 16%	Explore
naive B cell	6 studies	17% ± 1%	Explore
mast cell	5 studies	21% ± 4%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	32% ± 10%	Explore
progenitor cell	5 studies	26% ± 9%	Explore
renal alpha-intercalated cell	5 studies	34% ± 7%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	27% ± 8%	Explore
memory B cell	5 studies	17% ± 2%	Explore
duct epithelial cell	4 studies	27% ± 7%	Explore
pancreatic A cell	4 studies	51% ± 12%	Explore
type B pancreatic cell	4 studies	51% ± 25%	Explore
classical monocyte	4 studies	17% ± 2%	Explore
conventional dendritic cell	4 studies	23% ± 3%	Explore
exhausted T cell	4 studies	29% ± 5%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	33% ± 10%	Explore
lymphocyte	4 studies	27% ± 11%	Explore
myeloid cell	4 studies	23% ± 12%	Explore
astrocyte	4 studies	29% ± 2%	Explore
retinal cone cell	4 studies	36% ± 13%	Explore
adventitial cell	4 studies	35% ± 3%	Explore
Mueller cell	4 studies	23% ± 8%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	33% ± 8%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	28% ± 7%	Explore
hepatocyte	4 studies	49% ± 20%	Explore
luminal cell of prostate epithelium	4 studies	34% ± 10%	Explore
oligodendrocyte precursor cell	4 studies	28% ± 7%	Explore
hematopoietic stem cell	4 studies	26% ± 4%	Explore
T follicular helper cell	4 studies	18% ± 2%	Explore
transit amplifying cell	4 studies	26% ± 17%	Explore
oligodendrocyte	4 studies	24% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	20% ± 4%	Explore
ionocyte	3 studies	32% ± 6%	Explore
pancreatic D cell	3 studies	52% ± 20%	Explore
leukocyte	3 studies	23% ± 1%	Explore
glomerular endothelial cell	3 studies	24% ± 1%	Explore
epithelial cell of proximal tubule	3 studies	25% ± 5%	Explore
neural crest cell	3 studies	28% ± 7%	Explore
kidney loop of Henle epithelial cell	3 studies	39% ± 10%	Explore
extravillous trophoblast	3 studies	76% ± 16%	Explore
placental villous trophoblast	3 studies	56% ± 17%	Explore
retina horizontal cell	3 studies	22% ± 3%	Explore
retinal pigment epithelial cell	3 studies	37% ± 19%	Explore
retinal rod cell	3 studies	21% ± 3%	Explore
mucus secreting cell	3 studies	37% ± 9%	Explore
serous secreting cell	3 studies	23% ± 0%	Explore
innate lymphoid cell	3 studies	20% ± 1%	Explore
neuron	3 studies	28% ± 8%	Explore
IgM plasma cell	3 studies	45% ± 6%	Explore
GABAergic neuron	3 studies	36% ± 6%	Explore
glutamatergic neuron	3 studies	37% ± 10%	Explore
dendritic cell	3 studies	30% ± 10%	Explore
pancreatic ductal cell	3 studies	48% ± 18%	Explore
granulocyte monocyte progenitor cell	3 studies	34% ± 5%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	40% ± 18%	Explore
enterocyte	3 studies	19% ± 3%	Explore
enteroendocrine cell	3 studies	27% ± 7%	Explore
group 3 innate lymphoid cell	3 studies	27% ± 8%	Explore
erythroblast	3 studies	30% ± 9%	Explore
double negative thymocyte	3 studies	34% ± 10%	Explore
microglial cell	3 studies	19% ± 3%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	13 studies	28% ± 12%	Explore
peripheral blood	10 studies	21% ± 3%	Explore
intestine	7 studies	24% ± 9%	Explore
kidney	6 studies	24% ± 5%	Explore
liver	6 studies	26% ± 11%	Explore
brain	6 studies	27% ± 5%	Explore
pancreas	4 studies	48% ± 20%	Explore
bone marrow	4 studies	23% ± 6%	Explore
eye	4 studies	27% ± 5%	Explore
uterus	4 studies	38% ± 22%	Explore
placenta	3 studies	55% ± 16%	Explore
breast	3 studies	24% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	6160.30	245 / 245	100%	139.95	501 / 502
breast	100%	6155.36	459 / 459	100%	124.99	1114 / 1118
ovary	100%	7131.68	180 / 180	100%	69.18	428 / 430
esophagus	100%	4758.37	1445 / 1445	99%	95.68	182 / 183
lung	100%	7330.91	578 / 578	99%	106.91	1147 / 1155
thymus	100%	7902.49	653 / 653	98%	117.98	595 / 605
pancreas	100%	8054.94	328 / 328	98%	70.03	175 / 178
uterus	100%	6722.82	170 / 170	98%	89.77	451 / 459
kidney	100%	5059.62	89 / 89	98%	120.86	881 / 901
liver	100%	12683.55	226 / 226	97%	82.07	394 / 406
bladder	100%	5398.67	21 / 21	96%	72.36	485 / 504
stomach	100%	5571.89	359 / 359	95%	68.51	273 / 286
brain	97%	2509.20	2574 / 2642	98%	47.08	688 / 705
intestine	100%	4823.88	966 / 966	95%	65.35	500 / 527
skin	100%	8979.03	1803 / 1809	95%	86.31	447 / 472
adrenal gland	100%	7059.20	258 / 258	91%	50.71	210 / 230
adipose	100%	6403.42	1204 / 1204	0%	0	0 / 0
spleen	100%	4873.05	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	20.25	1 / 1
muscle	100%	4194.21	802 / 803	0%	0	0 / 0
blood vessel	100%	5480.98	1333 / 1335	0%	0	0 / 0
heart	99%	4914.77	851 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	116.21	44 / 45
lymph node	0%	0	0 / 0	83%	48.57	24 / 29
eye	0%	0	0 / 0	65%	28.68	52 / 80
peripheral blood	40%	3395.65	371 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0032527	Biological process	protein exit from endoplasmic reticulum
GO_0007029	Biological process	endoplasmic reticulum organization
GO_0034498	Biological process	early endosome to Golgi transport
GO_0007596	Biological process	blood coagulation
GO_0006457	Biological process	protein folding
GO_0007030	Biological process	Golgi organization
GO_0010638	Biological process	positive regulation of organelle organization
GO_0006888	Biological process	endoplasmic reticulum to Golgi vesicle-mediated transport
GO_1903215	Biological process	negative regulation of protein targeting to mitochondrion
GO_0016020	Cellular component	membrane
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0070062	Cellular component	extracellular exosome
GO_0062023	Cellular component	collagen-containing extracellular matrix
GO_0033116	Cellular component	endoplasmic reticulum-Golgi intermediate compartment membrane
GO_0000139	Cellular component	Golgi membrane
GO_0030017	Cellular component	sarcomere
GO_0005783	Cellular component	endoplasmic reticulum
GO_0005793	Cellular component	endoplasmic reticulum-Golgi intermediate compartment
GO_0030134	Cellular component	COPII-coated ER to Golgi transport vesicle
GO_0012507	Cellular component	ER to Golgi transport vesicle membrane
GO_0005537	Molecular function	D-mannose binding
GO_0051082	Molecular function	unfolded protein binding
GO_0046872	Molecular function	metal ion binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	LMAN1
Protein name	LMAN1 protein Protein ERGIC-53 (ER-Golgi intermediate compartment 53 kDa protein) (Gp58) (Intracellular mannose-specific lectin MR60) (Lectin mannose-binding 1)
Synonyms	ERGIC53 F5F8D
Description	FUNCTION: Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both. The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins. .
Accessions	A0PJ85 P49257 ENST00000251047.6

LMAN1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review