Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 17 studies | 36% ± 13% | |
| endothelial cell | 10 studies | 28% ± 7% | |
| type II pneumocyte | 9 studies | 26% ± 14% | |
| oligodendrocyte | 9 studies | 24% ± 9% | |
| epithelial cell | 8 studies | 33% ± 16% | |
| retinal ganglion cell | 6 studies | 57% ± 25% | |
| basal cell | 6 studies | 31% ± 9% | |
| fibroblast | 5 studies | 23% ± 5% | |
| connective tissue cell | 5 studies | 22% ± 9% | |
| abnormal cell | 5 studies | 22% ± 11% | |
| neuron | 5 studies | 35% ± 11% | |
| mesothelial cell | 4 studies | 26% ± 13% | |
| amacrine cell | 4 studies | 26% ± 3% | |
| club cell | 4 studies | 25% ± 5% | |
| retina horizontal cell | 4 studies | 39% ± 9% | |
| dendritic cell | 4 studies | 25% ± 5% | |
| GABAergic neuron | 4 studies | 32% ± 5% | |
| glutamatergic neuron | 4 studies | 40% ± 11% | |
| type I pneumocyte | 3 studies | 26% ± 7% | |
| deuterosomal cell | 3 studies | 20% ± 4% | |
| ionocyte | 3 studies | 25% ± 1% | |
| glomerular endothelial cell | 3 studies | 25% ± 3% | |
| neural crest cell | 3 studies | 16% ± 1% | |
| progenitor cell | 3 studies | 25% ± 3% | |
| smooth muscle cell | 3 studies | 19% ± 4% | |
| placental villous trophoblast | 3 studies | 26% ± 8% | |
| myeloid cell | 3 studies | 18% ± 2% | |
| astrocyte | 3 studies | 27% ± 7% | |
| mast cell | 3 studies | 31% ± 16% | |
| megakaryocyte-erythroid progenitor cell | 3 studies | 35% ± 4% | |
| pericyte | 3 studies | 29% ± 14% | |
| goblet cell | 3 studies | 30% ± 2% | |
| secretory cell | 3 studies | 31% ± 11% | |
| interneuron | 3 studies | 28% ± 14% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 95% | 2634.52 | 548 / 578 | 95% | 69.29 | 1096 / 1155 |
| brain | 93% | 1792.34 | 2454 / 2642 | 97% | 41.92 | 682 / 705 |
| skin | 100% | 4791.89 | 1809 / 1809 | 89% | 45.92 | 421 / 472 |
| uterus | 92% | 1557.59 | 156 / 170 | 95% | 69.51 | 436 / 459 |
| adrenal gland | 93% | 3162.69 | 241 / 258 | 87% | 88.66 | 201 / 230 |
| ovary | 84% | 1481.82 | 151 / 180 | 97% | 52.89 | 416 / 430 |
| prostate | 87% | 1006.80 | 214 / 245 | 91% | 36.88 | 459 / 502 |
| stomach | 81% | 1306.44 | 291 / 359 | 91% | 62.88 | 261 / 286 |
| liver | 82% | 2222.03 | 185 / 226 | 85% | 63.18 | 344 / 406 |
| breast | 67% | 705.12 | 308 / 459 | 98% | 92.42 | 1100 / 1118 |
| esophagus | 67% | 3183.71 | 961 / 1445 | 96% | 86.26 | 175 / 183 |
| bladder | 57% | 761.71 | 12 / 21 | 97% | 71.00 | 491 / 504 |
| intestine | 58% | 1060.50 | 565 / 966 | 95% | 72.13 | 501 / 527 |
| pancreas | 49% | 512.67 | 161 / 328 | 97% | 57.49 | 172 / 178 |
| kidney | 91% | 1208.66 | 81 / 89 | 38% | 8.84 | 344 / 901 |
| thymus | 84% | 883.33 | 546 / 653 | 33% | 7.97 | 197 / 605 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 71.37 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 51.49 | 1 / 1 |
| spleen | 94% | 1028.87 | 226 / 241 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 83% | 28.41 | 24 / 29 |
| blood vessel | 82% | 840.78 | 1099 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 75% | 821.71 | 902 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 50% | 22.54 | 40 / 80 |
| heart | 32% | 268.94 | 272 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 25% | 1628.58 | 231 / 929 | 0% | 0 | 0 / 0 |
| muscle | 0% | 1.74 | 2 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0008203 | Biological process | cholesterol metabolic process |
| GO_0140042 | Biological process | lipid droplet formation |
| GO_0016126 | Biological process | sterol biosynthetic process |
| GO_0042127 | Biological process | regulation of cell population proliferation |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0016020 | Cellular component | membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0071949 | Molecular function | FAD binding |
| GO_0004506 | Molecular function | squalene monooxygenase activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SQLE |
| Protein name | Squalene monooxygenase (EC 1.14.14.17) (Squalene epoxidase) (SE) Squalene monooxygenase (EC 1.14.14.17) |
| Synonyms | ERG1 |
| Description | FUNCTION: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis. . FUNCTION: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis. . FUNCTION: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis. . FUNCTION: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis. . |
| Accessions | E7EVQ6 ENST00000521232.1 ENST00000523430.5 E5RJH9 ENST00000265896.10 ENST00000518931.1 H0YBN7 Q14534 |