SQLE report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0008203Biological processcholesterol metabolic process
GO_0140042Biological processlipid droplet formation
GO_0016126Biological processsterol biosynthetic process
GO_0042127Biological processregulation of cell population proliferation
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0005783Cellular componentendoplasmic reticulum
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0071949Molecular functionFAD binding
GO_0004506Molecular functionsqualene monooxygenase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSQLE
Protein nameSqualene monooxygenase (EC 1.14.14.17) (Squalene epoxidase) (SE)
Squalene monooxygenase (EC 1.14.14.17)
SynonymsERG1
DescriptionFUNCTION: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis. .

FUNCTION: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis. .

FUNCTION: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis. .

FUNCTION: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis. .

AccessionsE7EVQ6
ENST00000521232.1
ENST00000523430.5
E5RJH9
ENST00000265896.10
ENST00000518931.1
H0YBN7
Q14534