Name | Number of supported studies | Average coverage | |
---|---|---|---|
hepatocyte | 6 studies | 67% ± 26% | |
goblet cell | 4 studies | 21% ± 2% | |
pancreatic A cell | 3 studies | 41% ± 19% | |
enterocyte | 3 studies | 21% ± 4% | |
enteroendocrine cell | 3 studies | 35% ± 8% | |
epithelial cell | 3 studies | 27% ± 10% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
liver | 3 studies | 45% ± 20% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 11727.03 | 226 / 226 | 98% | 46.30 | 396 / 406 |
kidney | 99% | 1162.62 | 88 / 89 | 56% | 8.70 | 509 / 901 |
intestine | 73% | 1151.92 | 701 / 966 | 74% | 6.27 | 389 / 527 |
stomach | 75% | 76.84 | 271 / 359 | 71% | 6.96 | 202 / 286 |
pancreas | 100% | 1373.19 | 328 / 328 | 42% | 2.96 | 74 / 178 |
bladder | 14% | 1.57 | 3 / 21 | 23% | 1.96 | 115 / 504 |
esophagus | 6% | 1.69 | 89 / 1445 | 27% | 2.98 | 49 / 183 |
adrenal gland | 26% | 3.47 | 67 / 258 | 0% | 0 | 0 / 230 |
lung | 16% | 3.12 | 95 / 578 | 9% | 0.75 | 104 / 1155 |
peripheral blood | 24% | 30.96 | 222 / 929 | 0% | 0 | 0 / 0 |
muscle | 19% | 2.57 | 151 / 803 | 0% | 0 | 0 / 0 |
prostate | 15% | 2.44 | 36 / 245 | 3% | 0.12 | 14 / 502 |
thymus | 14% | 1.87 | 90 / 653 | 0% | 0 | 0 / 605 |
breast | 14% | 7.68 | 62 / 459 | 0% | 0.01 | 2 / 1118 |
skin | 14% | 2.10 | 246 / 1809 | 0% | 0 | 0 / 472 |
blood vessel | 13% | 1.73 | 167 / 1335 | 0% | 0 | 0 / 0 |
ovary | 11% | 1.14 | 19 / 180 | 0% | 0.01 | 1 / 430 |
uterus | 7% | 1.04 | 12 / 170 | 3% | 0.12 | 13 / 459 |
heart | 8% | 1.19 | 66 / 861 | 0% | 0 | 0 / 0 |
brain | 8% | 1.08 | 200 / 2642 | 0% | 0 | 0 / 705 |
spleen | 6% | 14.59 | 14 / 241 | 0% | 0 | 0 / 0 |
adipose | 6% | 2.89 | 69 / 1204 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0010609 | Biological process | mRNA localization resulting in post-transcriptional regulation of gene expression |
GO_0006397 | Biological process | mRNA processing |
GO_0016554 | Biological process | cytidine to uridine editing |
GO_2000623 | Biological process | negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
GO_0050821 | Biological process | protein stabilization |
GO_0016556 | Biological process | mRNA modification |
GO_0007566 | Biological process | embryo implantation |
GO_0030895 | Cellular component | apolipoprotein B mRNA editing enzyme complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0005737 | Cellular component | cytoplasm |
GO_0045293 | Cellular component | mRNA editing complex |
GO_0005634 | Cellular component | nucleus |
GO_0003727 | Molecular function | single-stranded RNA binding |
GO_0140767 | Molecular function | enzyme-substrate adaptor activity |
GO_0003729 | Molecular function | mRNA binding |
GO_0003723 | Molecular function | RNA binding |
GO_0003725 | Molecular function | double-stranded RNA binding |
GO_0005515 | Molecular function | protein binding |
Gene name | A1CF |
Protein name | APOBEC1 complementation factor (APOBEC1-stimulating protein) A1CF protein APOBEC1 complementation factor |
Synonyms | ASP ACF |
Description | FUNCTION: Essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA. Binds to APOB mRNA and is probably responsible for docking the catalytic subunit, APOBEC1, to the mRNA to allow it to deaminate its target cytosine. The complex also protects the edited APOB mRNA from nonsense-mediated decay. . |
Accessions | ENST00000374001.6 [Q9NQ94-2] ENST00000373993.6 [Q9NQ94-1] Q9NQ94 ENST00000395495.6 [Q9NQ94-4] ENST00000373995.7 [Q9NQ94-4] ENST00000414883.2 [Q9NQ94-2] Q5T0W7 ENST00000373997.8 [Q9NQ94-2] ENST00000395489.7 ENST00000414883.2 F8W9F8 Q7Z2U9 |