TIMM50 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006470Biological processprotein dephosphorylation
GO_0007006Biological processmitochondrial membrane organization
GO_0030150Biological processprotein import into mitochondrial matrix
GO_0006886Biological processintracellular protein transport
GO_0001836Biological processrelease of cytochrome c from mitochondria
GO_0005739Cellular componentmitochondrion
GO_0016607Cellular componentnuclear speck
GO_0005654Cellular componentnucleoplasm
GO_0005794Cellular componentGolgi apparatus
GO_0005743Cellular componentmitochondrial inner membrane
GO_0005783Cellular componentendoplasmic reticulum
GO_0005744Cellular componentTIM23 mitochondrial import inner membrane translocase complex
GO_0004721Molecular functionphosphoprotein phosphatase activity
GO_0043021Molecular functionribonucleoprotein complex binding
GO_0003723Molecular functionRNA binding
GO_0004722Molecular functionprotein serine/threonine phosphatase activity
GO_0140608Molecular functioncysteine-type endopeptidase activator activity
GO_0005515Molecular functionprotein binding
GO_0005134Molecular functioninterleukin-2 receptor binding
GO_0004725Molecular functionprotein tyrosine phosphatase activity

IV. Literature review

[source]
Gene nameTIMM50
Protein nameMitochondrial import inner membrane translocase subunit TIM50
Translocase of inner mitochondrial membrane 50
SynonymsTIM50
PRO1512
DescriptionFUNCTION: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. .; FUNCTION: [Isoform 2]: May participate in the release of snRNPs and SMN from the Cajal body. .

FUNCTION: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. .

FUNCTION: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. .

FUNCTION: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. .

FUNCTION: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. .

FUNCTION: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. .

FUNCTION: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. .

AccessionsM0R003
ENST00000601252.1
Q3ZCQ8
M0R2Q2
ENST00000597782.5
ENST00000601403.5
ENST00000607714.6 [Q3ZCQ8-1]
ENST00000601358.5
ENST00000594583.2
M0R1Y4
ENST00000599733.5
ENST00000602265.5
M0R047
M0R2F8
M0QXC3
ENST00000544017.5 [Q3ZCQ8-2]
M0R303
ENST00000599794.5
ENST00000597666.5
M0R0C3
M0R2D2
ENST00000602028.5
Q0VAB1
M0R2Z3