I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| enterocyte | 7 studies | 52% ± 19% | |
| epithelial cell | 5 studies | 24% ± 8% | |
| Mueller cell | 4 studies | 42% ± 15% | |
| hepatocyte | 4 studies | 32% ± 6% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| enterocyte | 7 studies | 52% ± 19% | |
| epithelial cell | 5 studies | 24% ± 8% | |
| Mueller cell | 4 studies | 42% ± 15% | |
| hepatocyte | 4 studies | 32% ± 6% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| intestine | 3 studies | 22% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 6346.33 | 226 / 226 | 90% | 73.58 | 366 / 406 |
| brain | 86% | 54.76 | 2284 / 2642 | 75% | 4.01 | 528 / 705 |
| kidney | 97% | 316.65 | 86 / 89 | 16% | 1.16 | 148 / 901 |
| intestine | 78% | 1498.71 | 758 / 966 | 23% | 4.14 | 123 / 527 |
| ovary | 94% | 323.30 | 170 / 180 | 4% | 0.16 | 19 / 430 |
| heart | 89% | 90.72 | 767 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 78% | 54.53 | 1042 / 1335 | 0% | 0 | 0 / 0 |
| stomach | 41% | 39.78 | 146 / 359 | 33% | 4.09 | 95 / 286 |
| adrenal gland | 67% | 22.49 | 172 / 258 | 5% | 1.04 | 11 / 230 |
| esophagus | 49% | 30.92 | 712 / 1445 | 19% | 4.39 | 34 / 183 |
| bladder | 57% | 55.71 | 12 / 21 | 9% | 1.66 | 44 / 504 |
| muscle | 56% | 18.78 | 452 / 803 | 0% | 0 | 0 / 0 |
| lung | 36% | 11.82 | 209 / 578 | 14% | 1.28 | 158 / 1155 |
| prostate | 42% | 18.35 | 104 / 245 | 1% | 0.01 | 4 / 502 |
| skin | 21% | 6.11 | 384 / 1809 | 9% | 0.33 | 43 / 472 |
| adipose | 29% | 10.54 | 347 / 1204 | 0% | 0 | 0 / 0 |
| peripheral blood | 21% | 51.16 | 195 / 929 | 0% | 0 | 0 / 0 |
| breast | 19% | 7.37 | 85 / 459 | 2% | 0.04 | 18 / 1118 |
| pancreas | 7% | 1.36 | 22 / 328 | 12% | 1.54 | 22 / 178 |
| thymus | 11% | 2.85 | 71 / 653 | 1% | 0.02 | 7 / 605 |
| uterus | 5% | 2.43 | 8 / 170 | 6% | 1.04 | 28 / 459 |
| spleen | 8% | 11.27 | 20 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 4% | 0.05 | 2 / 45 |
| eye | 0% | 0 | 0 / 0 | 4% | 0.07 | 3 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.04 | 1 / 29 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_1902389 | Biological process | ceramide 1-phosphate transport |
| GO_0015914 | Biological process | phospholipid transport |
| GO_0015918 | Biological process | sterol transport |
| GO_0120009 | Biological process | intermembrane lipid transfer |
| GO_0034379 | Biological process | very-low-density lipoprotein particle assembly |
| GO_0034197 | Biological process | triglyceride transport |
| GO_0042157 | Biological process | lipoprotein metabolic process |
| GO_0051649 | Biological process | establishment of localization in cell |
| GO_0007623 | Biological process | circadian rhythm |
| GO_0042632 | Biological process | cholesterol homeostasis |
| GO_0034374 | Biological process | low-density lipoprotein particle remodeling |
| GO_0034377 | Biological process | plasma lipoprotein particle assembly |
| GO_0006641 | Biological process | triglyceride metabolic process |
| GO_0034378 | Biological process | chylomicron assembly |
| GO_0042953 | Biological process | lipoprotein transport |
| GO_0006629 | Biological process | lipid metabolic process |
| GO_0051592 | Biological process | response to calcium ion |
| GO_0009306 | Biological process | protein secretion |
| GO_0031526 | Cellular component | brush border membrane |
| GO_0043235 | Cellular component | receptor complex |
| GO_0031982 | Cellular component | vesicle |
| GO_0031528 | Cellular component | microvillus membrane |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005788 | Cellular component | endoplasmic reticulum lumen |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005829 | Cellular component | cytosol |
| GO_0016323 | Cellular component | basolateral plasma membrane |
| GO_1902388 | Molecular function | ceramide 1-phosphate transfer activity |
| GO_0008289 | Molecular function | lipid binding |
| GO_0120020 | Molecular function | cholesterol transfer activity |
| GO_0044877 | Molecular function | protein-containing complex binding |
| GO_0034185 | Molecular function | apolipoprotein binding |
| GO_0120014 | Molecular function | phospholipid transfer activity |
| GO_0005548 | Molecular function | phospholipid transporter activity |
| GO_0005319 | Molecular function | lipid transporter activity |
| GO_0046982 | Molecular function | protein heterodimerization activity |
| GO_0140344 | Molecular function | triglyceride transfer activity |
| GO_0120019 | Molecular function | phosphatidylcholine transfer activity |
| GO_0005515 | Molecular function | protein binding |
| GO_1904121 | Molecular function | phosphatidylethanolamine transfer activity |
| Gene name | MTTP |
| Protein name | Microsomal triglyceride transfer protein Microsomal triglyceride transfer protein large subunit |
| Synonyms | MTP |
| Description | FUNCTION: Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces . Required for the assembly and secretion of plasma lipoproteins that contain apolipoprotein B . May be involved in regulating cholesteryl ester biosynthesis in cells that produce lipoproteins (By similarity). . |
| Accessions | D6RAB8 ENST00000457717.6 [P55157-1] D6R915 ENST00000511610.6 ENST00000511045.6 E9PBP6 ENST00000505094.6 ENST00000265517.10 [P55157-1] P55157 ENST00000422897.6 [P55157-2] |
