MGAT4A | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	27 studies	26% ± 8%	Explore
endothelial cell	27 studies	25% ± 8%	Explore
T cell	26 studies	26% ± 9%	Explore
macrophage	26 studies	29% ± 16%	Explore
CD4-positive, alpha-beta T cell	26 studies	31% ± 11%	Explore
CD8-positive, alpha-beta T cell	24 studies	28% ± 11%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	17 studies	35% ± 13%	Explore
mucosal invariant T cell	16 studies	37% ± 14%	Explore
microglial cell	15 studies	56% ± 23%	Explore
plasmacytoid dendritic cell	15 studies	28% ± 10%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	38% ± 15%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	31% ± 9%	Explore
mature NK T cell	13 studies	29% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	25% ± 6%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	36% ± 10%	Explore
glutamatergic neuron	10 studies	35% ± 23%	Explore
gamma-delta T cell	10 studies	28% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell	9 studies	31% ± 13%	Explore
regulatory T cell	9 studies	22% ± 5%	Explore
myeloid cell	9 studies	27% ± 9%	Explore
capillary endothelial cell	9 studies	20% ± 3%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	32% ± 12%	Explore
leukocyte	7 studies	39% ± 20%	Explore
monocyte	7 studies	22% ± 7%	Explore
endothelial cell of vascular tree	7 studies	24% ± 12%	Explore
oligodendrocyte	7 studies	24% ± 10%	Explore
classical monocyte	6 studies	20% ± 3%	Explore
oligodendrocyte precursor cell	6 studies	28% ± 9%	Explore
vein endothelial cell	6 studies	28% ± 14%	Explore
GABAergic neuron	5 studies	41% ± 18%	Explore
epithelial cell	5 studies	26% ± 4%	Explore
dendritic cell	5 studies	24% ± 9%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	37% ± 14%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	24% ± 3%	Explore
granule cell	4 studies	23% ± 5%	Explore
endothelial cell of artery	4 studies	19% ± 2%	Explore
lymphocyte	4 studies	36% ± 16%	Explore
conventional dendritic cell	4 studies	21% ± 2%	Explore
astrocyte	4 studies	29% ± 11%	Explore
innate lymphoid cell	4 studies	29% ± 6%	Explore
goblet cell	4 studies	35% ± 27%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	27% ± 4%	Explore
double negative thymocyte	4 studies	36% ± 8%	Explore
interneuron	4 studies	40% ± 13%	Explore
CD4-positive helper T cell	3 studies	34% ± 13%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	28% ± 3%	Explore
neuron	3 studies	26% ± 12%	Explore
enterocyte	3 studies	23% ± 3%	Explore
mononuclear phagocyte	3 studies	23% ± 4%	Explore
enteroendocrine cell	3 studies	24% ± 1%	Explore
alveolar macrophage	3 studies	31% ± 11%	Explore
T follicular helper cell	3 studies	40% ± 6%	Explore
group 3 innate lymphoid cell	3 studies	36% ± 1%	Explore
T-helper 17 cell	3 studies	37% ± 14%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	39% ± 9%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	32% ± 8%	Explore
double-positive, alpha-beta thymocyte	3 studies	43% ± 14%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	14 studies	27% ± 7%	Explore
brain	12 studies	32% ± 17%	Explore
lung	4 studies	20% ± 3%	Explore
intestine	4 studies	18% ± 1%	Explore
kidney	4 studies	16% ± 1%	Explore
lymph node	3 studies	20% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	2900.66	2638 / 2642	100%	16.53	703 / 705
stomach	100%	1974.04	359 / 359	99%	20.85	283 / 286
pancreas	100%	4524.46	328 / 328	99%	15.95	176 / 178
prostate	100%	2073.23	244 / 245	99%	22.24	498 / 502
breast	100%	2404.44	459 / 459	99%	41.21	1103 / 1118
thymus	100%	2072.24	653 / 653	98%	13.14	594 / 605
intestine	100%	3448.62	966 / 966	97%	19.60	511 / 527
kidney	100%	2644.00	89 / 89	96%	25.63	865 / 901
lung	100%	4112.65	578 / 578	90%	15.82	1042 / 1155
bladder	100%	1609.24	21 / 21	88%	15.71	442 / 504
ovary	88%	721.84	159 / 180	88%	9.70	378 / 430
uterus	100%	1903.11	170 / 170	76%	9.33	349 / 459
esophagus	99%	1216.00	1435 / 1445	74%	15.35	136 / 183
liver	97%	832.62	220 / 226	75%	7.66	306 / 406
adrenal gland	96%	932.66	247 / 258	73%	18.56	169 / 230
skin	69%	605.34	1253 / 1809	78%	8.88	366 / 472
adipose	100%	2310.68	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	14.52	29 / 29
spleen	100%	1737.20	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	13.59	1 / 1
blood vessel	100%	1594.81	1332 / 1335	0%	0	0 / 0
heart	97%	1117.33	838 / 861	0%	0	0 / 0
muscle	88%	629.69	705 / 803	0%	0	0 / 0
peripheral blood	84%	1400.40	785 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	79%	10.23	63 / 80
tonsil	0%	0	0 / 0	71%	6.66	32 / 45
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006486	Biological process	protein glycosylation
GO_0046487	Biological process	glyoxylate metabolic process
GO_0006487	Biological process	protein N-linked glycosylation
GO_0019082	Biological process	viral protein processing
GO_0006491	Biological process	N-glycan processing
GO_0005795	Cellular component	Golgi stack
GO_0000139	Cellular component	Golgi membrane
GO_0005788	Cellular component	endoplasmic reticulum lumen
GO_0005783	Cellular component	endoplasmic reticulum
GO_0070062	Cellular component	extracellular exosome
GO_0005777	Cellular component	peroxisome
GO_0005793	Cellular component	endoplasmic reticulum-Golgi intermediate compartment
GO_0008375	Molecular function	acetylglucosaminyltransferase activity
GO_0042803	Molecular function	protein homodimerization activity
GO_0008453	Molecular function	alanine-glyoxylate transaminase activity
GO_0008454	Molecular function	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity
GO_0046872	Molecular function	metal ion binding

IV. Literature review

[source]

Gene name	MGAT4A
Protein name	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVa) (GlcNAc-T IVa) (GnT-IVa) (N-acetylglucosaminyltransferase IVa) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVa) [Cleaved into: Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A soluble form] Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
Synonyms
Description	FUNCTION: Glycosyltransferase that catalyze the transfer of GlcNAc from UDP-GlcNAc to the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans through a beta1-4 linkage and participates in the production of tri- and tetra-antennary N-linked sugar chains . Involved in glucose transport by mediating SLC2A2/GLUT2 glycosylation, thereby controlling cell-surface expression of SLC2A2 in pancreatic beta cells (By similarity). .
Accessions	ENST00000495056.2 ENST00000409391.1 [Q9UM21-1] Q9UM21 ENST00000393487.6 [Q9UM21-1] ENST00000264968.7 [Q9UM21-1] ENST00000414521.6 [Q9UM21-2] U3KPT4

MGAT4A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review