CLDN8 | OmnibusX

Name	Number of supported studies	Average coverage
renal alpha-intercalated cell	4 studies	56% ± 1%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of CLDN8 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	98%	807.18	641 / 653	79%	26.65	480 / 605
prostate	77%	400.64	189 / 245	98%	108.10	494 / 502
breast	61%	1282.31	282 / 459	52%	15.97	585 / 1118
kidney	100%	2012.84	89 / 89	13%	32.69	116 / 901
skin	70%	494.29	1273 / 1809	0%	0.09	2 / 472
esophagus	33%	124.78	475 / 1445	19%	5.74	35 / 183
lung	20%	70.64	117 / 578	26%	10.39	295 / 1155
intestine	31%	527.39	300 / 966	10%	2.44	51 / 527
bladder	5%	10.14	1 / 21	12%	3.57	62 / 504
uterus	2%	7.01	3 / 170	12%	4.11	55 / 459
stomach	0%	0.33	1 / 359	5%	1.55	14 / 286
pancreas	0%	0.40	1 / 328	2%	1.41	4 / 178
tonsil	0%	0	0 / 0	2%	0.98	1 / 45
ovary	0%	0	0 / 180	2%	0.19	9 / 430
adipose	2%	10.67	22 / 1204	0%	0	0 / 0
liver	0%	0	0 / 226	0%	0.04	2 / 406
adrenal gland	0%	0.57	1 / 258	0%	0	0 / 230
blood vessel	0%	0.51	2 / 1335	0%	0	0 / 0
heart	0%	1.17	1 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
brain	0%	0	0 / 2642	0%	0	0 / 705
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
muscle	0%	0	0 / 803	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0016338	Biological process	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
GO_0007155	Biological process	cell adhesion
GO_0070830	Biological process	bicellular tight junction assembly
GO_0016327	Cellular component	apicolateral plasma membrane
GO_0005783	Cellular component	endoplasmic reticulum
GO_0005886	Cellular component	plasma membrane
GO_0016323	Cellular component	basolateral plasma membrane
GO_0005923	Cellular component	bicellular tight junction
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding
GO_0005198	Molecular function	structural molecule activity

Gene name	CLDN8
Protein name	Claudin-8
Synonyms	UNQ779/PRO1573
Description	FUNCTION: Tight-junction protein required for paracellular chloride transport in the kidney. Mediates recruitment of CLDN4 to tight junction in the kidney. Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. .
Accessions	P56748 ENST00000399899.2

CLDN8 report