PSMG1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0080129Biological processproteasome core complex assembly
GO_0021930Biological processcerebellar granule cell precursor proliferation
GO_0051131Biological processchaperone-mediated protein complex assembly
GO_0101031Cellular componentprotein folding chaperone complex
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005783Cellular componentendoplasmic reticulum
GO_0005794Cellular componentGolgi apparatus
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0070628Molecular functionproteasome binding
GO_0005515Molecular functionprotein binding
GO_0060090Molecular functionmolecular adaptor activity

IV. Literature review

[source]
Gene namePSMG1
Protein nameProteasome assembly chaperone 1 (PAC-1) (Chromosome 21 leucine-rich protein) (C21-LRP) (Down syndrome critical region protein 2)
Proteasome assembly chaperone 1
SynonymsDSCR2
PAC1
C21LRP
DescriptionFUNCTION: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization. .

AccessionsENST00000331573.8 [O95456-1]
ENST00000380900.2 [O95456-2]
ENST00000411828.5
F8WBH7
H7C3B4
ENST00000431628.1
O95456