Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 8 studies | 26% ± 7% | |
type II pneumocyte | 5 studies | 28% ± 5% | |
GABAergic neuron | 4 studies | 35% ± 18% | |
glutamatergic neuron | 4 studies | 49% ± 20% | |
epithelial cell | 3 studies | 29% ± 7% | |
mesothelial cell | 3 studies | 16% ± 1% | |
ciliated cell | 3 studies | 23% ± 7% | |
respiratory goblet cell | 3 studies | 33% ± 12% | |
granule cell | 3 studies | 22% ± 7% | |
renal alpha-intercalated cell | 3 studies | 28% ± 7% | |
renal principal cell | 3 studies | 22% ± 4% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 3 studies | 36% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 100% | 1202.13 | 89 / 89 | 96% | 68.11 | 866 / 901 |
thymus | 100% | 1218.85 | 651 / 653 | 90% | 37.84 | 543 / 605 |
stomach | 72% | 1007.19 | 260 / 359 | 93% | 63.14 | 267 / 286 |
lung | 64% | 743.97 | 368 / 578 | 95% | 88.09 | 1100 / 1155 |
adrenal gland | 83% | 998.34 | 213 / 258 | 74% | 36.92 | 171 / 230 |
pancreas | 62% | 220.23 | 203 / 328 | 91% | 71.70 | 162 / 178 |
intestine | 51% | 711.14 | 493 / 966 | 97% | 61.47 | 512 / 527 |
esophagus | 39% | 1031.19 | 570 / 1445 | 95% | 98.81 | 173 / 183 |
ovary | 14% | 44.94 | 26 / 180 | 94% | 54.46 | 403 / 430 |
bladder | 33% | 592.81 | 7 / 21 | 71% | 34.38 | 360 / 504 |
brain | 85% | 730.71 | 2257 / 2642 | 16% | 2.48 | 114 / 705 |
tonsil | 0% | 0 | 0 / 0 | 96% | 86.00 | 43 / 45 |
uterus | 22% | 123.74 | 38 / 170 | 72% | 40.22 | 330 / 459 |
lymph node | 0% | 0 | 0 / 0 | 83% | 21.63 | 24 / 29 |
skin | 73% | 1902.89 | 1317 / 1809 | 4% | 1.28 | 21 / 472 |
prostate | 27% | 115.02 | 67 / 245 | 23% | 4.11 | 117 / 502 |
breast | 22% | 81.99 | 99 / 459 | 28% | 8.30 | 317 / 1118 |
heart | 49% | 362.68 | 424 / 861 | 0% | 0 | 0 / 0 |
spleen | 33% | 98.31 | 79 / 241 | 0% | 0 | 0 / 0 |
adipose | 28% | 195.53 | 338 / 1204 | 0% | 0 | 0 / 0 |
peripheral blood | 20% | 993.65 | 185 / 929 | 0% | 0 | 0 / 0 |
liver | 1% | 3.83 | 3 / 226 | 15% | 8.69 | 60 / 406 |
muscle | 7% | 27.51 | 53 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 2% | 10.11 | 33 / 1335 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0061469 | Biological process | regulation of type B pancreatic cell proliferation |
GO_0006670 | Biological process | sphingosine metabolic process |
GO_0030149 | Biological process | sphingolipid catabolic process |
GO_0046839 | Biological process | phospholipid dephosphorylation |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0070780 | Molecular function | dihydrosphingosine-1-phosphate phosphatase activity |
GO_0042392 | Molecular function | sphingosine-1-phosphate phosphatase activity |
Gene name | SGPP2 |
Protein name | SGPP2 protein Sphingosine-1-phosphate phosphatase 2 (SPPase2) (Spp2) (hSPP2) (EC 3.1.3.-) (Sphingosine-1-phosphatase 2) Uncharacterized protein SGPP2 |
Synonyms | |
Description | FUNCTION: Has specific phosphohydrolase activity towards sphingoid base 1-phosphates. Has high phosphohydrolase activity against dihydrosphingosine-1-phosphate and sphingosine-1-phosphate (S1P) in vitro . Sphingosine-1-phosphate phosphatase activity is needed for efficient recycling of sphingosine into the sphingolipid synthesis pathway (By similarity). May play a role in attenuating intracellular sphingosine 1-phosphate (S1P) signaling. May play a role in pro-inflammatory signaling . Plays a role in the regulation of pancreatic islet beta-cell endoplasmic reticulum stress and proliferation (By similarity). . |
Accessions | Q53QF5 Q3B870 Q4ZFX2 Q8IWX5 ENST00000321276.8 [Q8IWX5-1] |