ZDHHC1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ZDHHC1 at tissue level.

III. Associated gene sets

GO_0018345Biological processprotein palmitoylation
GO_0018230Biological processpeptidyl-L-cysteine S-palmitoylation
GO_0140374Biological processantiviral innate immune response
GO_0006612Biological processprotein targeting to membrane
GO_0002230Biological processpositive regulation of defense response to virus by host
GO_0010008Cellular componentendosome membrane
GO_0070062Cellular componentextracellular exosome
GO_0005783Cellular componentendoplasmic reticulum
GO_0005794Cellular componentGolgi apparatus
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0016409Molecular functionpalmitoyltransferase activity
GO_0003677Molecular functionDNA binding
GO_0019706Molecular functionprotein-cysteine S-palmitoyltransferase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameZDHHC1
Protein namePalmitoyltransferase ZDHHC1 (EC 2.3.1.225) (DHHC domain-containing cysteine-rich protein 1) (Zinc finger DHHC domain-containing protein 1) (DHHC-1) (Zinc finger protein 377)
Palmitoyltransferase (EC 2.3.1.225)
SynonymsC16orf1
ZNF377
DescriptionFUNCTION: Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates (By similarity). Has a palmitoyltransferase activity toward NCDN and regulates NCDN association with endosome membranes through this palmitoylation. .; FUNCTION: Has also a palmitoyltransferase activity-independent function in DNA virus-triggered and CGAS-mediated innate immune response . Functions as an activator of STING1 by promoting its cGAMP-induced oligomerization and the recruitment of downstream signaling components . .

AccessionsI3L202
ENST00000348579.6
Q8WTX9
ENST00000565726.3