DPM3 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
ciliated cell	16 studies	35% ± 16%	Explore
endothelial cell	15 studies	28% ± 11%	Explore
fibroblast	13 studies	25% ± 11%	Explore
natural killer cell	12 studies	19% ± 5%	Explore
plasma cell	12 studies	32% ± 12%	Explore
classical monocyte	11 studies	22% ± 6%	Explore
pericyte	11 studies	21% ± 4%	Explore
epithelial cell	10 studies	38% ± 22%	Explore
smooth muscle cell	10 studies	23% ± 7%	Explore
connective tissue cell	8 studies	23% ± 5%	Explore
endothelial cell of lymphatic vessel	8 studies	22% ± 5%	Explore
basal cell	7 studies	30% ± 14%	Explore
secretory cell	7 studies	22% ± 8%	Explore
CD16-negative, CD56-bright natural killer cell, human	7 studies	18% ± 2%	Explore
conventional dendritic cell	7 studies	26% ± 11%	Explore
goblet cell	7 studies	29% ± 13%	Explore
CD16-positive, CD56-dim natural killer cell, human	6 studies	19% ± 3%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	18% ± 3%	Explore
capillary endothelial cell	6 studies	21% ± 3%	Explore
macrophage	6 studies	24% ± 6%	Explore
endothelial cell of artery	6 studies	18% ± 2%	Explore
CD8-positive, alpha-beta T cell	6 studies	19% ± 2%	Explore
abnormal cell	6 studies	22% ± 7%	Explore
plasmacytoid dendritic cell	6 studies	22% ± 5%	Explore
club cell	5 studies	27% ± 7%	Explore
monocyte	5 studies	20% ± 3%	Explore
non-classical monocyte	5 studies	24% ± 6%	Explore
kidney loop of Henle epithelial cell	5 studies	26% ± 10%	Explore
myofibroblast cell	5 studies	24% ± 2%	Explore
progenitor cell	5 studies	32% ± 13%	Explore
transit amplifying cell	5 studies	20% ± 2%	Explore
B cell	5 studies	19% ± 4%	Explore
type II pneumocyte	5 studies	31% ± 19%	Explore
mast cell	5 studies	19% ± 3%	Explore
hematopoietic precursor cell	4 studies	26% ± 8%	Explore
plasmablast	4 studies	40% ± 20%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	19% ± 4%	Explore
CD4-positive, alpha-beta T cell	4 studies	19% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	20% ± 1%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	36% ± 9%	Explore
epithelial cell of proximal tubule	4 studies	22% ± 4%	Explore
endothelial cell of vascular tree	4 studies	21% ± 4%	Explore
regulatory T cell	4 studies	19% ± 2%	Explore
enteroendocrine cell	4 studies	32% ± 17%	Explore
vein endothelial cell	4 studies	16% ± 0%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	20% ± 3%	Explore
pancreatic A cell	3 studies	44% ± 5%	Explore
type B pancreatic cell	3 studies	37% ± 12%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	19% ± 3%	Explore
glomerular endothelial cell	3 studies	22% ± 1%	Explore
mature NK T cell	3 studies	16% ± 1%	Explore
T cell	3 studies	22% ± 6%	Explore
renal alpha-intercalated cell	3 studies	42% ± 16%	Explore
common myeloid progenitor	3 studies	33% ± 11%	Explore
lymphocyte	3 studies	23% ± 9%	Explore
enterocyte	3 studies	20% ± 2%	Explore
retinal cone cell	3 studies	37% ± 10%	Explore
exhausted T cell	3 studies	16% ± 0%	Explore
intermediate monocyte	3 studies	25% ± 10%	Explore
dendritic cell	3 studies	37% ± 14%	Explore
hematopoietic stem cell	3 studies	21% ± 4%	Explore
gamma-delta T cell	3 studies	30% ± 15%	Explore
mucosal invariant T cell	3 studies	20% ± 3%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	21% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	9 studies	20% ± 4%	Explore
lung	8 studies	27% ± 6%	Explore
intestine	6 studies	22% ± 8%	Explore
kidney	5 studies	22% ± 6%	Explore
uterus	4 studies	27% ± 15%	Explore
pancreas	3 studies	33% ± 13%	Explore
eye	3 studies	24% ± 6%	Explore
brain	3 studies	19% ± 2%	Explore
liver	3 studies	31% ± 16%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	1484.51	258 / 258	100%	164.03	230 / 230
liver	100%	858.53	226 / 226	100%	178.19	406 / 406
ovary	100%	866.80	180 / 180	100%	225.19	430 / 430
thymus	100%	1177.91	653 / 653	100%	181.07	605 / 605
brain	100%	676.02	2638 / 2642	100%	126.93	705 / 705
uterus	100%	1056.27	170 / 170	100%	157.03	457 / 459
prostate	100%	1028.11	245 / 245	99%	200.63	498 / 502
pancreas	100%	702.63	328 / 328	99%	118.02	176 / 178
intestine	100%	977.73	966 / 966	99%	139.39	521 / 527
esophagus	100%	807.05	1444 / 1445	98%	81.90	180 / 183
stomach	100%	806.74	359 / 359	98%	115.69	281 / 286
bladder	100%	847.05	21 / 21	98%	167.03	494 / 504
skin	100%	735.89	1808 / 1809	98%	125.00	462 / 472
breast	100%	931.00	459 / 459	98%	123.98	1092 / 1118
lung	100%	798.75	576 / 578	97%	113.30	1125 / 1155
kidney	100%	1074.74	89 / 89	97%	89.39	874 / 901
eye	0%	0	0 / 0	100%	125.44	80 / 80
lymph node	0%	0	0 / 0	100%	119.25	29 / 29
spleen	100%	961.69	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	317.08	1 / 1
blood vessel	100%	757.92	1333 / 1335	0%	0	0 / 0
adipose	100%	799.07	1202 / 1204	0%	0	0 / 0
heart	99%	619.54	852 / 861	0%	0	0 / 0
muscle	99%	516.63	794 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	93%	72.20	42 / 45
peripheral blood	92%	379.58	856 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0031647	Biological process	regulation of protein stability
GO_0005975	Biological process	carbohydrate metabolic process
GO_0035268	Biological process	protein mannosylation
GO_0018406	Biological process	protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan
GO_0019348	Biological process	dolichol metabolic process
GO_0006506	Biological process	GPI anchor biosynthetic process
GO_0035269	Biological process	protein O-linked mannosylation
GO_0005783	Cellular component	endoplasmic reticulum
GO_0033185	Cellular component	dolichol-phosphate-mannose synthase complex
GO_0016020	Cellular component	membrane
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0031501	Cellular component	mannosyltransferase complex
GO_0008047	Molecular function	enzyme activator activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	DPM3
Protein name	Dolichol-phosphate mannosyltransferase subunit 3 (Dolichol-phosphate mannose synthase subunit 3) (DPM synthase subunit 3) (Dolichyl-phosphate beta-D-mannosyltransferase subunit 3) (Mannose-P-dolichol synthase subunit 3) (MPD synthase subunit 3) (Prostin-1) Dolichol-phosphate mannosyltransferase subunit 3
Synonyms
Description	FUNCTION: Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit DPM1 to the endoplasmic reticulum. . FUNCTION: Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. . FUNCTION: Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. . FUNCTION: Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. .
Accessions	Q86TM7 Q3SX58 ENST00000341298.3 [Q9P2X0-1] ENST00000368400.5 [Q9P2X0-1] ENST00000368399.1 [Q9P2X0-2] Q6P184 Q9P2X0

DPM3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review