I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| fibroblast | 7 studies | 27% ± 11% | |
| connective tissue cell | 3 studies | 35% ± 23% | |
| epithelial cell | 3 studies | 30% ± 4% | |
| goblet cell | 3 studies | 26% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| fibroblast | 7 studies | 27% ± 11% | |
| connective tissue cell | 3 studies | 35% ± 23% | |
| epithelial cell | 3 studies | 30% ± 4% | |
| goblet cell | 3 studies | 26% ± 5% |
Insufficient scRNA-seq data for expression of KDELR3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 99% | 664.31 | 326 / 328 | 98% | 77.76 | 175 / 178 |
| stomach | 98% | 692.11 | 352 / 359 | 99% | 85.86 | 284 / 286 |
| lung | 100% | 825.07 | 576 / 578 | 97% | 79.98 | 1126 / 1155 |
| prostate | 99% | 640.95 | 243 / 245 | 97% | 57.78 | 488 / 502 |
| breast | 100% | 733.55 | 458 / 459 | 96% | 80.60 | 1072 / 1118 |
| intestine | 95% | 463.14 | 913 / 966 | 98% | 78.81 | 519 / 527 |
| skin | 83% | 2211.13 | 1499 / 1809 | 98% | 106.44 | 463 / 472 |
| thymus | 99% | 537.71 | 646 / 653 | 80% | 37.56 | 486 / 605 |
| bladder | 90% | 440.24 | 19 / 21 | 85% | 51.53 | 430 / 504 |
| esophagus | 82% | 293.41 | 1179 / 1445 | 94% | 67.23 | 172 / 183 |
| uterus | 94% | 384.24 | 160 / 170 | 81% | 44.17 | 370 / 459 |
| kidney | 99% | 576.76 | 88 / 89 | 76% | 36.17 | 682 / 901 |
| ovary | 70% | 249.95 | 126 / 180 | 94% | 56.62 | 406 / 430 |
| liver | 91% | 539.74 | 205 / 226 | 74% | 39.24 | 299 / 406 |
| adrenal gland | 92% | 331.98 | 238 / 258 | 29% | 9.84 | 67 / 230 |
| adipose | 100% | 985.95 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 18.16 | 1 / 1 |
| eye | 0% | 0 | 0 / 0 | 99% | 72.42 | 79 / 80 |
| heart | 97% | 535.01 | 831 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 96% | 847.65 | 1283 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 81% | 182.60 | 196 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 76% | 21.75 | 34 / 45 |
| brain | 15% | 26.63 | 388 / 2642 | 15% | 5.43 | 104 / 705 |
| lymph node | 0% | 0 | 0 / 0 | 21% | 3.18 | 6 / 29 |
| muscle | 17% | 36.32 | 139 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 7% | 14.20 | 67 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0015031 | Biological process | protein transport |
| GO_0006888 | Biological process | endoplasmic reticulum to Golgi vesicle-mediated transport |
| GO_0006890 | Biological process | retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum |
| GO_0006621 | Biological process | protein retention in ER lumen |
| GO_0030663 | Cellular component | COPI-coated vesicle membrane |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0005801 | Cellular component | cis-Golgi network |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0030133 | Cellular component | transport vesicle |
| GO_0005046 | Molecular function | KDEL sequence binding |
| GO_0046923 | Molecular function | ER retention sequence binding |
| Gene name | KDELR3 |
| Protein name | ER lumen protein-retaining receptor 3 (KDEL endoplasmic reticulum protein retention receptor 3) (KDEL receptor 3) |
| Synonyms | ERD23 |
| Description | FUNCTION: Receptor for the C-terminal sequence motif K-D-E-L that is present on endoplasmic reticulum resident proteins and that mediates their recycling from the Golgi back to the endoplasmic reticulum. . |
| Accessions | ENST00000216014.9 [O43731-1] ENST00000409006.3 [O43731-2] O43731 |
