SULF2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0003094Biological processglomerular filtration
GO_0090263Biological processpositive regulation of canonical Wnt signaling pathway
GO_0035860Biological processglial cell-derived neurotrophic factor receptor signaling pathway
GO_2000345Biological processregulation of hepatocyte proliferation
GO_0014846Biological processesophagus smooth muscle contraction
GO_0001822Biological processkidney development
GO_0032836Biological processglomerular basement membrane development
GO_0030201Biological processheparan sulfate proteoglycan metabolic process
GO_0002063Biological processchondrocyte development
GO_0097421Biological processliver regeneration
GO_0048706Biological processembryonic skeletal system development
GO_0010575Biological processpositive regulation of vascular endothelial growth factor production
GO_1904472Biological processpositive regulation of endothelin production
GO_0060348Biological processbone development
GO_0060384Biological processinnervation
GO_0051216Biological processcartilage development
GO_0009611Biological processresponse to wounding
GO_0030177Biological processpositive regulation of Wnt signaling pathway
GO_0040037Biological processnegative regulation of fibroblast growth factor receptor signaling pathway
GO_0005795Cellular componentGolgi stack
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0005886Cellular componentplasma membrane
GO_0009986Cellular componentcell surface
GO_0005783Cellular componentendoplasmic reticulum
GO_0004065Molecular functionarylsulfatase activity
GO_0005539Molecular functionglycosaminoglycan binding
GO_0005509Molecular functioncalcium ion binding
GO_0008449Molecular functionN-acetylglucosamine-6-sulfatase activity

IV. Literature review

[source]
Gene nameSULF2
Protein nameSulfatase 2
Extracellular sulfatase Sulf-2 (hSulf-2) (Arylsulfatase) (EC 3.1.6.1) (N-acetylglucosamine-6-sulfatase) (EC 3.1.6.14) [Cleaved into: Extracellular sulfatase Sulf-2 secreted form]
SULF2 protein
SynonymsUNQ559/PRO1120
KIAA1247
DescriptionFUNCTION: Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity . It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin . .

AccessionsH0Y872
Q8IWU5
ENST00000359930.8 [Q8IWU5-1]
ENST00000495544.5
Q5BKT1
ENST00000484875.5 [Q8IWU5-1]
A0A8V8TMY2
ENST00000698128.1
B1AMP9
ENST00000437955.1
ENST00000688720.1 [Q8IWU5-1]
ENST00000467815.5 [Q8IWU5-2]
Q6DKK3