SEC31A | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	40 studies	33% ± 13%	Explore
endothelial cell	28 studies	32% ± 14%	Explore
pericyte	28 studies	29% ± 13%	Explore
smooth muscle cell	24 studies	26% ± 7%	Explore
macrophage	20 studies	26% ± 12%	Explore
natural killer cell	16 studies	19% ± 3%	Explore
endothelial cell of lymphatic vessel	14 studies	24% ± 9%	Explore
plasma cell	14 studies	31% ± 13%	Explore
plasmacytoid dendritic cell	14 studies	31% ± 9%	Explore
ciliated cell	13 studies	30% ± 12%	Explore
epithelial cell	13 studies	40% ± 23%	Explore
classical monocyte	12 studies	23% ± 10%	Explore
B cell	12 studies	21% ± 4%	Explore
myofibroblast cell	12 studies	32% ± 11%	Explore
basal cell	11 studies	30% ± 17%	Explore
connective tissue cell	11 studies	37% ± 16%	Explore
microglial cell	11 studies	30% ± 12%	Explore
oligodendrocyte precursor cell	11 studies	30% ± 12%	Explore
mast cell	11 studies	26% ± 9%	Explore
astrocyte	11 studies	31% ± 12%	Explore
oligodendrocyte	11 studies	28% ± 10%	Explore
type I pneumocyte	10 studies	32% ± 7%	Explore
adipocyte	10 studies	44% ± 10%	Explore
club cell	9 studies	33% ± 13%	Explore
naive B cell	9 studies	19% ± 2%	Explore
GABAergic neuron	9 studies	36% ± 20%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	19% ± 3%	Explore
CD16-positive, CD56-dim natural killer cell, human	9 studies	22% ± 3%	Explore
myeloid cell	9 studies	29% ± 7%	Explore
capillary endothelial cell	8 studies	18% ± 3%	Explore
goblet cell	8 studies	36% ± 24%	Explore
glutamatergic neuron	8 studies	43% ± 26%	Explore
dendritic cell	8 studies	28% ± 16%	Explore
T cell	7 studies	20% ± 4%	Explore
neuron	7 studies	34% ± 18%	Explore
endothelial cell of artery	7 studies	17% ± 3%	Explore
interneuron	7 studies	37% ± 20%	Explore
regulatory T cell	7 studies	18% ± 3%	Explore
type II pneumocyte	7 studies	31% ± 7%	Explore
monocyte	7 studies	26% ± 5%	Explore
plasmablast	6 studies	39% ± 17%	Explore
respiratory goblet cell	6 studies	41% ± 14%	Explore
secretory cell	6 studies	26% ± 6%	Explore
non-classical monocyte	6 studies	29% ± 11%	Explore
conventional dendritic cell	6 studies	28% ± 13%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	19% ± 3%	Explore
abnormal cell	6 studies	33% ± 16%	Explore
memory B cell	6 studies	18% ± 2%	Explore
mucosal invariant T cell	6 studies	21% ± 3%	Explore
vein endothelial cell	6 studies	25% ± 15%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	20% ± 3%	Explore
gamma-delta T cell	6 studies	23% ± 8%	Explore
hematopoietic precursor cell	5 studies	33% ± 12%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	5 studies	18% ± 2%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	19% ± 3%	Explore
mature NK T cell	5 studies	22% ± 7%	Explore
progenitor cell	5 studies	25% ± 6%	Explore
epithelial cell of proximal tubule	5 studies	20% ± 4%	Explore
enterocyte	5 studies	20% ± 3%	Explore
CD8-positive, alpha-beta T cell	5 studies	21% ± 4%	Explore
retina horizontal cell	5 studies	20% ± 5%	Explore
adventitial cell	5 studies	24% ± 7%	Explore
mucus secreting cell	5 studies	34% ± 13%	Explore
cardiac muscle cell	5 studies	31% ± 5%	Explore
mesothelial cell	5 studies	35% ± 9%	Explore
endothelial cell of vascular tree	5 studies	28% ± 13%	Explore
squamous epithelial cell	4 studies	38% ± 22%	Explore
leukocyte	4 studies	21% ± 4%	Explore
CD4-positive, alpha-beta T cell	4 studies	21% ± 5%	Explore
glial cell	4 studies	24% ± 6%	Explore
pro-B cell	4 studies	23% ± 6%	Explore
lymphocyte	4 studies	30% ± 11%	Explore
Mueller cell	4 studies	19% ± 5%	Explore
hepatocyte	4 studies	61% ± 17%	Explore
hematopoietic stem cell	4 studies	24% ± 7%	Explore
enteroendocrine cell	4 studies	25% ± 8%	Explore
alveolar macrophage	4 studies	29% ± 10%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	20% ± 5%	Explore
pancreatic A cell	3 studies	50% ± 21%	Explore
type B pancreatic cell	3 studies	57% ± 23%	Explore
granule cell	3 studies	22% ± 4%	Explore
retinal ganglion cell	3 studies	31% ± 5%	Explore
precursor B cell	3 studies	20% ± 3%	Explore
amacrine cell	3 studies	18% ± 1%	Explore
retinal bipolar neuron	3 studies	17% ± 1%	Explore
retinal pigment epithelial cell	3 studies	38% ± 23%	Explore
serous secreting cell	3 studies	17% ± 2%	Explore
mononuclear phagocyte	3 studies	26% ± 7%	Explore
retinal rod cell	3 studies	19% ± 4%	Explore
rod bipolar cell	3 studies	21% ± 3%	Explore
innate lymphoid cell	3 studies	19% ± 2%	Explore
muscle cell	3 studies	40% ± 16%	Explore
granulocyte monocyte progenitor cell	3 studies	28% ± 15%	Explore
chondrocyte	3 studies	44% ± 9%	Explore
double negative thymocyte	3 studies	27% ± 8%	Explore
kidney loop of Henle epithelial cell	3 studies	20% ± 1%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	14 studies	26% ± 8%	Explore
brain	14 studies	34% ± 18%	Explore
peripheral blood	10 studies	22% ± 7%	Explore
eye	6 studies	26% ± 17%	Explore
intestine	6 studies	24% ± 10%	Explore
kidney	5 studies	20% ± 4%	Explore
heart	5 studies	28% ± 6%	Explore
liver	5 studies	31% ± 19%	Explore
uterus	4 studies	28% ± 13%	Explore
adipose	4 studies	38% ± 16%	Explore
pancreas	3 studies	53% ± 22%	Explore
bone marrow	3 studies	31% ± 14%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	10852.31	459 / 459	100%	107.26	1118 / 1118
esophagus	100%	9573.82	1445 / 1445	100%	86.32	183 / 183
lung	100%	10777.57	578 / 578	100%	77.17	1155 / 1155
ovary	100%	17640.34	180 / 180	100%	67.13	430 / 430
prostate	100%	10427.80	245 / 245	100%	86.82	502 / 502
skin	100%	14640.37	1808 / 1809	100%	90.97	472 / 472
stomach	100%	7906.27	359 / 359	100%	64.69	285 / 286
adrenal gland	100%	11123.76	258 / 258	100%	69.10	229 / 230
kidney	100%	7841.54	89 / 89	100%	77.35	897 / 901
thymus	100%	11170.49	653 / 653	100%	75.01	602 / 605
pancreas	100%	10783.13	328 / 328	99%	75.86	177 / 178
intestine	100%	9625.42	966 / 966	99%	55.68	524 / 527
bladder	100%	10364.71	21 / 21	99%	56.22	501 / 504
liver	100%	6871.95	226 / 226	99%	46.29	403 / 406
uterus	100%	13814.86	170 / 170	99%	63.16	455 / 459
brain	95%	4312.39	2509 / 2642	100%	46.02	702 / 705
adipose	100%	11746.51	1204 / 1204	0%	0	0 / 0
blood vessel	100%	16170.35	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	59.89	80 / 80
muscle	100%	7110.60	803 / 803	0%	0	0 / 0
spleen	100%	7210.04	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	59.02	45 / 45
ureter	0%	0	0 / 0	100%	20.02	1 / 1
heart	97%	7370.88	836 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	90%	34.04	26 / 29
peripheral blood	69%	4462.62	642 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0007029	Biological process	endoplasmic reticulum organization
GO_0015031	Biological process	protein transport
GO_0006888	Biological process	endoplasmic reticulum to Golgi vesicle-mediated transport
GO_0051592	Biological process	response to calcium ion
GO_0090110	Biological process	COPII-coated vesicle cargo loading
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0030127	Cellular component	COPII vesicle coat
GO_0030120	Cellular component	vesicle coat
GO_0070971	Cellular component	endoplasmic reticulum exit site
GO_0005783	Cellular component	endoplasmic reticulum
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0030134	Cellular component	COPII-coated ER to Golgi transport vesicle
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0012507	Cellular component	ER to Golgi transport vesicle membrane
GO_0005198	Molecular function	structural molecule activity
GO_0048306	Molecular function	calcium-dependent protein binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	SEC31A
Protein name	SEC31 homolog A, COPII coat complex component Protein transport protein Sec31A (ABP125) (ABP130) (SEC31-like protein 1) (SEC31-related protein A) (Web1-like protein) Protein transport protein Sec31A (SEC31-like protein 1) (SEC31-related protein A)
Synonyms	SEC31L1 KIAA0905 HSPC334 HSPC275
Description	FUNCTION: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER) . The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). .
Accessions	ENST00000503937.5 ENST00000311785.11 [O94979-3] ENST00000395310.7 [O94979-1] ENST00000508479.5 ENST00000348405.8 [O94979-4] ENST00000448323.5 [O94979-1] H0Y8W8 H0Y9K1 D6RCQ9 D6REA9 ENST00000512664.5 ENST00000508502.5 [O94979-2] H0Y8V7 D6RAB3 O94979 ENST00000513858.5 [O94979-6] ENST00000507340.5 ENST00000505472.5 H0Y9V3 D6REC0 D6RHE8 ENST00000507816.5 ENST00000515062.5 ENST00000505984.5 [O94979-10] ENST00000507676.5 ENST00000264405.9 ENST00000503210.5 U3KQC9 D6RHZ5 D6RBT0 ENST00000507828.5 A0A1S5UZ19 ENST00000509142.5 [O94979-3] ENST00000511338.1 ENST00000503058.5 H0YAF5 ENST00000506495.5 ENST00000510167.1 ENST00000514326.5 ENST00000513323.5 D6RE64 H0Y9T9 H7BXG7 U3KQR3 ENST00000505434.5 ENST00000500777.6 [O94979-6] ENST00000355196.6 [O94979-1] ENST00000443462.6 [O94979-9] H0YAB3 D6REX3 ENST00000507051.1

SEC31A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review