CDKAL1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1990145Biological processmaintenance of translational fidelity
GO_0035600Biological processtRNA methylthiolation
GO_0008150Biological processbiological_process
GO_0005783Cellular componentendoplasmic reticulum
GO_0005791Cellular componentrough endoplasmic reticulum
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005515Molecular functionprotein binding
GO_0051539Molecular function4 iron, 4 sulfur cluster binding
GO_0035598Molecular functionN6-threonylcarbomyladenosine methylthiotransferase activity
GO_0046872Molecular functionmetal ion binding
GO_0061712Molecular functiontRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase

IV. Literature review

[source]
Gene nameCDKAL1
Protein nameThreonylcarbamoyladenosine tRNA methylthiotransferase (EC 2.8.4.5) (CDK5 regulatory subunit-associated protein 1-like 1) (tRNA-t(6)A37 methylthiotransferase)
Synonyms
DescriptionFUNCTION: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine. .

AccessionsENST00000378610.1 [Q5VV42-1]
Q5VV42
ENST00000274695.8 [Q5VV42-1]
ENST00000613575.4 [Q5VV42-3]