AGPAT5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006654Biological processphosphatidic acid biosynthetic process
GO_0002244Biological processhematopoietic progenitor cell differentiation
GO_0008654Biological processphospholipid biosynthetic process
GO_0016024Biological processCDP-diacylglycerol biosynthetic process
GO_0036149Biological processphosphatidylinositol acyl-chain remodeling
GO_0006639Biological processacylglycerol metabolic process
GO_0005741Cellular componentmitochondrial outer membrane
GO_0005730Cellular componentnucleolus
GO_0005783Cellular componentendoplasmic reticulum
GO_0005635Cellular componentnuclear envelope
GO_0012505Cellular componentendomembrane system
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005739Cellular componentmitochondrion
GO_0003841Molecular function1-acylglycerol-3-phosphate O-acyltransferase activity
GO_0016746Molecular functionacyltransferase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameAGPAT5
Protein name1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 5) (1-AGP acyltransferase 5) (1-AGPAT 5) (Lysophosphatidic acid acyltransferase epsilon) (LPAAT-epsilon)
1-acylglycerol-3-phosphate O-acyltransferase 5
1-acylglycerol-3-phosphate O-acyltransferase 5 (Lysophosphatidic acid acyltransferase, epsilon), isoform CRA_a (Testicular tissue protein Li 144)
AGPAT5 protein
SynonymshCG_22281
DescriptionFUNCTION: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone . Acts on LPA containing saturated or unsaturated fatty acids C15:0-C20:4 at the sn-1 position using C18:1-CoA as the acyl donor . Also acts on lysophosphatidylethanolamine using oleoyl-CoA, but not arachidonoyl-CoA, and lysophosphatidylinositol using arachidonoyl-CoA, but not oleoyl-CoA . Activity toward lysophosphatidylglycerol not detectable . .

AccessionsE5RH21
Q9NUQ2
Q6NUM7
ENST00000518327.1
H0YC22
ENST00000285518.11
ENST00000523234.5
H0YAW1
ENST00000523586.1
A0A024R640
ENST00000646327.2