Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| naive B cell | 8 studies | 20% ± 2% | |
| astrocyte | 8 studies | 28% ± 12% | |
| endothelial cell | 7 studies | 28% ± 13% | |
| oligodendrocyte precursor cell | 7 studies | 25% ± 11% | |
| neuron | 6 studies | 31% ± 20% | |
| epithelial cell | 6 studies | 27% ± 8% | |
| oligodendrocyte | 6 studies | 23% ± 4% | |
| interneuron | 5 studies | 37% ± 24% | |
| microglial cell | 5 studies | 25% ± 6% | |
| B cell | 4 studies | 18% ± 5% | |
| plasmacytoid dendritic cell | 4 studies | 24% ± 8% | |
| macrophage | 3 studies | 25% ± 3% | |
| ciliated cell | 3 studies | 27% ± 6% | |
| innate lymphoid cell | 3 studies | 19% ± 2% | |
| abnormal cell | 3 studies | 29% ± 4% | |
| group 3 innate lymphoid cell | 3 studies | 28% ± 1% | |
| GABAergic neuron | 3 studies | 40% ± 17% | |
| glutamatergic neuron | 3 studies | 46% ± 18% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 2533.38 | 2642 / 2642 | 100% | 76.05 | 705 / 705 |
| esophagus | 98% | 859.25 | 1420 / 1445 | 100% | 28.45 | 183 / 183 |
| breast | 100% | 949.49 | 458 / 459 | 98% | 21.57 | 1100 / 1118 |
| prostate | 100% | 1176.66 | 244 / 245 | 98% | 21.65 | 494 / 502 |
| kidney | 100% | 1085.00 | 89 / 89 | 98% | 27.66 | 882 / 901 |
| intestine | 98% | 1087.24 | 946 / 966 | 100% | 28.33 | 526 / 527 |
| ovary | 100% | 1030.86 | 180 / 180 | 97% | 16.16 | 418 / 430 |
| stomach | 99% | 975.74 | 355 / 359 | 98% | 27.41 | 281 / 286 |
| thymus | 99% | 805.31 | 649 / 653 | 98% | 16.86 | 591 / 605 |
| uterus | 99% | 1231.24 | 169 / 170 | 98% | 20.96 | 448 / 459 |
| lung | 98% | 858.87 | 569 / 578 | 98% | 18.34 | 1136 / 1155 |
| adrenal gland | 100% | 2045.07 | 258 / 258 | 96% | 17.48 | 221 / 230 |
| bladder | 100% | 865.29 | 21 / 21 | 95% | 18.65 | 479 / 504 |
| pancreas | 96% | 641.68 | 315 / 328 | 98% | 15.05 | 175 / 178 |
| skin | 96% | 1086.40 | 1744 / 1809 | 94% | 22.62 | 444 / 472 |
| liver | 97% | 936.83 | 220 / 226 | 75% | 10.53 | 304 / 406 |
| spleen | 100% | 877.45 | 241 / 241 | 0% | 0 | 0 / 0 |
| adipose | 100% | 983.92 | 1202 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 100% | 1187.49 | 801 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 726.26 | 1316 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 22.57 | 44 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 21.33 | 28 / 29 |
| eye | 0% | 0 | 0 / 0 | 80% | 11.23 | 64 / 80 |
| heart | 63% | 314.24 | 539 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 34% | 2404.27 | 319 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006654 | Biological process | phosphatidic acid biosynthetic process |
| GO_0002244 | Biological process | hematopoietic progenitor cell differentiation |
| GO_0008654 | Biological process | phospholipid biosynthetic process |
| GO_0016024 | Biological process | CDP-diacylglycerol biosynthetic process |
| GO_0036149 | Biological process | phosphatidylinositol acyl-chain remodeling |
| GO_0006639 | Biological process | acylglycerol metabolic process |
| GO_0005741 | Cellular component | mitochondrial outer membrane |
| GO_0005730 | Cellular component | nucleolus |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005635 | Cellular component | nuclear envelope |
| GO_0012505 | Cellular component | endomembrane system |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0003841 | Molecular function | 1-acylglycerol-3-phosphate O-acyltransferase activity |
| GO_0016746 | Molecular function | acyltransferase activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | AGPAT5 |
| Protein name | 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 5) (1-AGP acyltransferase 5) (1-AGPAT 5) (Lysophosphatidic acid acyltransferase epsilon) (LPAAT-epsilon) 1-acylglycerol-3-phosphate O-acyltransferase 5 1-acylglycerol-3-phosphate O-acyltransferase 5 (Lysophosphatidic acid acyltransferase, epsilon), isoform CRA_a (Testicular tissue protein Li 144) AGPAT5 protein |
| Synonyms | hCG_22281 |
| Description | FUNCTION: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone . Acts on LPA containing saturated or unsaturated fatty acids C15:0-C20:4 at the sn-1 position using C18:1-CoA as the acyl donor . Also acts on lysophosphatidylethanolamine using oleoyl-CoA, but not arachidonoyl-CoA, and lysophosphatidylinositol using arachidonoyl-CoA, but not oleoyl-CoA . Activity toward lysophosphatidylglycerol not detectable . . |
| Accessions | E5RH21 Q9NUQ2 Q6NUM7 ENST00000518327.1 H0YC22 ENST00000285518.11 ENST00000523234.5 H0YAW1 ENST00000523586.1 A0A024R640 ENST00000646327.2 |