Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 17 studies | 36% ± 19% | |
| fibroblast | 15 studies | 31% ± 17% | |
| endothelial cell | 10 studies | 34% ± 14% | |
| adipocyte | 10 studies | 39% ± 10% | |
| mesothelial cell | 9 studies | 34% ± 11% | |
| epithelial cell | 7 studies | 37% ± 14% | |
| oligodendrocyte precursor cell | 6 studies | 28% ± 13% | |
| Mueller cell | 6 studies | 32% ± 19% | |
| pericyte | 6 studies | 28% ± 21% | |
| GABAergic neuron | 5 studies | 28% ± 9% | |
| abnormal cell | 5 studies | 40% ± 24% | |
| cardiac muscle cell | 5 studies | 20% ± 2% | |
| smooth muscle cell | 5 studies | 20% ± 5% | |
| basal cell | 4 studies | 22% ± 3% | |
| retinal rod cell | 4 studies | 37% ± 14% | |
| connective tissue cell | 4 studies | 40% ± 27% | |
| myofibroblast cell | 4 studies | 20% ± 4% | |
| pancreatic A cell | 3 studies | 39% ± 5% | |
| type B pancreatic cell | 3 studies | 43% ± 16% | |
| podocyte | 3 studies | 41% ± 18% | |
| kidney distal convoluted tubule epithelial cell | 3 studies | 22% ± 6% | |
| extravillous trophoblast | 3 studies | 29% ± 7% | |
| retinal cone cell | 3 studies | 33% ± 14% | |
| retinal pigment epithelial cell | 3 studies | 29% ± 11% | |
| ciliated cell | 3 studies | 27% ± 8% | |
| chondrocyte | 3 studies | 34% ± 18% | |
| cholangiocyte | 3 studies | 42% ± 26% | |
| glutamatergic neuron | 3 studies | 36% ± 5% | |
| ependymal cell | 3 studies | 37% ± 17% | |
| megakaryocyte-erythroid progenitor cell | 3 studies | 19% ± 4% | |
| enterocyte | 3 studies | 19% ± 2% | |
| interneuron | 3 studies | 34% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| kidney | 100% | 2357.11 | 89 / 89 | 97% | 107.34 | 873 / 901 |
| thymus | 100% | 6127.39 | 653 / 653 | 96% | 98.42 | 578 / 605 |
| uterus | 99% | 3207.51 | 168 / 170 | 95% | 64.85 | 434 / 459 |
| ovary | 100% | 3276.61 | 180 / 180 | 90% | 35.81 | 388 / 430 |
| lung | 99% | 2359.16 | 574 / 578 | 90% | 55.97 | 1037 / 1155 |
| breast | 99% | 3403.78 | 455 / 459 | 87% | 39.14 | 969 / 1118 |
| pancreas | 95% | 1853.94 | 312 / 328 | 89% | 37.04 | 159 / 178 |
| esophagus | 99% | 3344.25 | 1436 / 1445 | 84% | 38.68 | 153 / 183 |
| liver | 100% | 4998.12 | 225 / 226 | 82% | 32.08 | 334 / 406 |
| intestine | 100% | 3647.70 | 964 / 966 | 81% | 28.92 | 428 / 527 |
| stomach | 100% | 2690.83 | 359 / 359 | 80% | 27.73 | 228 / 286 |
| bladder | 100% | 3573.76 | 21 / 21 | 77% | 36.08 | 386 / 504 |
| brain | 85% | 1334.39 | 2257 / 2642 | 79% | 26.44 | 556 / 705 |
| adrenal gland | 100% | 3098.31 | 258 / 258 | 53% | 13.70 | 121 / 230 |
| prostate | 93% | 1664.82 | 227 / 245 | 38% | 7.71 | 193 / 502 |
| skin | 54% | 9272.11 | 971 / 1809 | 65% | 22.28 | 306 / 472 |
| adipose | 100% | 5424.50 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 5680.01 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 48.94 | 43 / 45 |
| heart | 88% | 2048.27 | 761 / 861 | 0% | 0 | 0 / 0 |
| spleen | 41% | 397.02 | 99 / 241 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 14% | 2.14 | 4 / 29 |
| muscle | 7% | 71.81 | 58 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 6% | 0.87 | 5 / 80 |
| peripheral blood | 2% | 18.70 | 15 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0046947 | Biological process | hydroxylysine biosynthetic process |
| GO_0036211 | Biological process | protein modification process |
| GO_0017185 | Biological process | peptidyl-lysine hydroxylation |
| GO_0001666 | Biological process | response to hypoxia |
| GO_0006493 | Biological process | protein O-linked glycosylation |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0030867 | Cellular component | rough endoplasmic reticulum membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0033823 | Molecular function | procollagen glucosyltransferase activity |
| GO_0005506 | Molecular function | iron ion binding |
| GO_0008475 | Molecular function | procollagen-lysine 5-dioxygenase activity |
| GO_0031418 | Molecular function | L-ascorbic acid binding |
| Gene name | PLOD2 |
| Protein name | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 procollagen-lysine 5-dioxygenase (EC 1.14.11.4) Lysyl hydroxylase 2 PLOD2 protein Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 (EC 1.14.11.4) (Lysyl hydroxylase 2) (LH2) |
| Synonyms | |
| Description | FUNCTION: Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links. . |
| Accessions | F8WEW3 ENST00000703518.1 [O00469-2] Q96QU5 ENST00000706626.1 A0A994J3M7 ENST00000703527.1 [O00469-2] A0A994J6E6 A0A994J6S5 ENST00000703528.1 ENST00000480704.2 ENST00000703521.1 ENST00000494950.5 ENST00000461497.5 [O00469-3] ENST00000703520.1 ENST00000703522.1 [O00469-2] ENST00000282903.10 [O00469-2] O00469 A0A9L9PX47 ENST00000703523.1 [O00469-1] C9JXZ0 Q96AR9 ENST00000469350.6 E7ETU9 ENST00000360060.7 [O00469-1] ENST00000706636.1 A0A9L9PXC2 ENST00000706635.1 |