PLOD2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0046947Biological processhydroxylysine biosynthetic process
GO_0036211Biological processprotein modification process
GO_0017185Biological processpeptidyl-lysine hydroxylation
GO_0001666Biological processresponse to hypoxia
GO_0006493Biological processprotein O-linked glycosylation
GO_0070062Cellular componentextracellular exosome
GO_0005783Cellular componentendoplasmic reticulum
GO_0030867Cellular componentrough endoplasmic reticulum membrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0033823Molecular functionprocollagen glucosyltransferase activity
GO_0005506Molecular functioniron ion binding
GO_0008475Molecular functionprocollagen-lysine 5-dioxygenase activity
GO_0031418Molecular functionL-ascorbic acid binding

IV. Literature review

[source]
Gene namePLOD2
Protein nameProcollagen-lysine,2-oxoglutarate 5-dioxygenase 2
procollagen-lysine 5-dioxygenase (EC 1.14.11.4)
Lysyl hydroxylase 2
PLOD2 protein
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 (EC 1.14.11.4) (Lysyl hydroxylase 2) (LH2)
Synonyms
DescriptionFUNCTION: Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links. .

AccessionsF8WEW3
ENST00000703518.1 [O00469-2]
Q96QU5
ENST00000706626.1
A0A994J3M7
ENST00000703527.1 [O00469-2]
A0A994J6E6
A0A994J6S5
ENST00000703528.1
ENST00000480704.2
ENST00000703521.1
ENST00000494950.5
ENST00000461497.5 [O00469-3]
ENST00000703520.1
ENST00000703522.1 [O00469-2]
ENST00000282903.10 [O00469-2]
O00469
A0A9L9PX47
ENST00000703523.1 [O00469-1]
C9JXZ0
Q96AR9
ENST00000469350.6
E7ETU9
ENST00000360060.7 [O00469-1]
ENST00000706636.1
A0A9L9PXC2
ENST00000706635.1