Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| non-classical monocyte | 24 studies | 58% ± 21% | |
| classical monocyte | 20 studies | 31% ± 15% | |
| monocyte | 15 studies | 27% ± 10% | |
| macrophage | 12 studies | 28% ± 10% | |
| conventional dendritic cell | 9 studies | 27% ± 17% | |
| dendritic cell | 7 studies | 29% ± 17% | |
| myeloid cell | 5 studies | 23% ± 8% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| peripheral blood | 3 studies | 19% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 100% | 1275.88 | 578 / 578 | 92% | 12.24 | 1058 / 1155 |
| breast | 86% | 321.59 | 397 / 459 | 92% | 9.64 | 1028 / 1118 |
| bladder | 100% | 320.52 | 21 / 21 | 63% | 7.36 | 320 / 504 |
| intestine | 87% | 327.71 | 841 / 966 | 75% | 7.47 | 394 / 527 |
| adrenal gland | 100% | 866.70 | 257 / 258 | 57% | 11.18 | 131 / 230 |
| kidney | 54% | 195.18 | 48 / 89 | 92% | 19.82 | 830 / 901 |
| stomach | 58% | 180.85 | 210 / 359 | 82% | 9.20 | 235 / 286 |
| esophagus | 62% | 190.98 | 899 / 1445 | 70% | 5.58 | 129 / 183 |
| uterus | 57% | 137.74 | 97 / 170 | 74% | 6.84 | 341 / 459 |
| ovary | 41% | 90.83 | 74 / 180 | 87% | 10.68 | 375 / 430 |
| prostate | 69% | 200.76 | 170 / 245 | 56% | 3.09 | 282 / 502 |
| liver | 56% | 193.13 | 127 / 226 | 69% | 6.58 | 279 / 406 |
| thymus | 45% | 109.12 | 291 / 653 | 72% | 5.46 | 433 / 605 |
| pancreas | 32% | 77.55 | 104 / 328 | 84% | 10.34 | 150 / 178 |
| skin | 23% | 43.88 | 417 / 1809 | 86% | 13.79 | 405 / 472 |
| brain | 20% | 47.43 | 541 / 2642 | 81% | 11.10 | 569 / 705 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 37.86 | 29 / 29 |
| spleen | 100% | 6063.04 | 241 / 241 | 0% | 0 | 0 / 0 |
| adipose | 97% | 701.46 | 1171 / 1204 | 0% | 0 | 0 / 0 |
| peripheral blood | 95% | 11266.98 | 881 / 929 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 87% | 9.34 | 39 / 45 |
| blood vessel | 72% | 360.53 | 957 / 1335 | 0% | 0 | 0 / 0 |
| heart | 53% | 138.45 | 457 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 46% | 3.06 | 37 / 80 |
| muscle | 45% | 109.52 | 365 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005829 | Cellular component | cytosol |
| GO_0015630 | Cellular component | microtubule cytoskeleton |
| GO_0016020 | Cellular component | membrane |
| GO_0005515 | Molecular function | protein binding |
| Gene name | LRRC25 |
| Protein name | LRRC25 protein (Leucine rich repeat containing 25, isoform CRA_a) Leucine-rich repeat-containing protein 25 (Monocyte and plasmacytoid-activated protein) |
| Synonyms | MAPA UNQ6169/PRO20174 hCG_1776913 |
| Description | FUNCTION: Plays a role in the inhibition of RLR-mediated type I interferon signaling pathway by targeting RIGI for autophagic degradation. Interacts specifically with ISG15-associated RIGI to promote interaction between RIGI and the autophagic cargo receptor p62/SQSTM1 to mediate RIGI degradation via selective autophagy . Also plays a role in the inhibition of NF-kappa-B signaling pathway and inflammatory response by promoting the degradation of p65/RELA. . |
| Accessions | Q8TAB8 ENST00000595840.1 ENST00000339007.4 Q8N386 |
