I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| goblet cell | 5 studies | 32% ± 14% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| goblet cell | 5 studies | 32% ± 14% |
Insufficient scRNA-seq data for expression of ANO7 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 14461.04 | 245 / 245 | 100% | 110.92 | 501 / 502 |
| ovary | 100% | 176.97 | 180 / 180 | 90% | 3.70 | 389 / 430 |
| intestine | 96% | 2276.88 | 923 / 966 | 84% | 5.75 | 445 / 527 |
| stomach | 97% | 1942.53 | 349 / 359 | 81% | 3.42 | 231 / 286 |
| thymus | 100% | 92.67 | 650 / 653 | 75% | 1.40 | 454 / 605 |
| pancreas | 92% | 55.00 | 301 / 328 | 81% | 3.79 | 144 / 178 |
| kidney | 98% | 99.42 | 87 / 89 | 73% | 1.64 | 660 / 901 |
| lung | 98% | 74.99 | 567 / 578 | 68% | 1.81 | 781 / 1155 |
| bladder | 100% | 92.76 | 21 / 21 | 63% | 1.95 | 320 / 504 |
| skin | 89% | 72.42 | 1608 / 1809 | 68% | 1.69 | 321 / 472 |
| liver | 98% | 83.86 | 221 / 226 | 52% | 1.16 | 212 / 406 |
| uterus | 99% | 148.02 | 169 / 170 | 49% | 1.22 | 226 / 459 |
| esophagus | 75% | 47.49 | 1088 / 1445 | 71% | 2.76 | 130 / 183 |
| breast | 93% | 86.83 | 429 / 459 | 48% | 1.62 | 538 / 1118 |
| brain | 99% | 121.64 | 2614 / 2642 | 35% | 0.61 | 244 / 705 |
| adrenal gland | 100% | 125.00 | 258 / 258 | 23% | 0.51 | 53 / 230 |
| spleen | 100% | 104.51 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 3.38 | 1 / 1 |
| eye | 0% | 0 | 0 / 0 | 90% | 2.12 | 72 / 80 |
| heart | 89% | 48.02 | 768 / 861 | 0% | 0 | 0 / 0 |
| adipose | 89% | 51.97 | 1067 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 51% | 22.34 | 683 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 40% | 35.59 | 369 / 929 | 0% | 0 | 0 / 0 |
| muscle | 35% | 11.69 | 281 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 28% | 0.34 | 8 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 24% | 0.30 | 11 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0034220 | Biological process | monoatomic ion transmembrane transport |
| GO_0061588 | Biological process | calcium activated phospholipid scrambling |
| GO_1902476 | Biological process | chloride transmembrane transport |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005829 | Cellular component | cytosol |
| GO_0070161 | Cellular component | anchoring junction |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0046983 | Molecular function | protein dimerization activity |
| GO_0005229 | Molecular function | intracellularly calcium-gated chloride channel activity |
| GO_0005254 | Molecular function | chloride channel activity |
| Gene name | ANO7 |
| Protein name | Anoctamin-7 (Dresden transmembrane protein of the prostate) (D-TMPP) (IPCA-5) (New gene expressed in prostate) (Prostate cancer-associated protein 5) (Transmembrane protein 16G) Anoctamin Anoctamin 7 ANO7 protein |
| Synonyms | TMEM16G PCANAP5 NGEP |
| Description | FUNCTION: Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium-activated chloride channel (CaCC) activity . May play a role in cell-cell interactions . . |
| Accessions | ENST00000274979.12 [Q6IWH7-1] A0A6Q8JT31 ENST00000402430.8 ENST00000674324.2 A0A6Q8JTU6 A0A6I8PRE6 ENST00000402530.8 Q6IWH7 ENST00000451047.1 H7C220 Q8N348 |
