Insufficient scRNA-seq data for expression of ALG10B at single-cell level.
Insufficient scRNA-seq data for expression of ALG10B at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 962.04 | 180 / 180 | 99% | 4.50 | 427 / 430 |
brain | 99% | 439.06 | 2625 / 2642 | 100% | 5.01 | 704 / 705 |
prostate | 100% | 636.39 | 245 / 245 | 99% | 4.62 | 496 / 502 |
thymus | 100% | 922.58 | 653 / 653 | 98% | 4.20 | 595 / 605 |
adrenal gland | 100% | 789.41 | 258 / 258 | 98% | 3.61 | 225 / 230 |
breast | 100% | 897.82 | 459 / 459 | 97% | 5.36 | 1089 / 1118 |
kidney | 100% | 514.49 | 89 / 89 | 97% | 4.43 | 872 / 901 |
lung | 100% | 700.35 | 576 / 578 | 97% | 4.04 | 1117 / 1155 |
uterus | 100% | 893.11 | 170 / 170 | 96% | 4.31 | 441 / 459 |
esophagus | 100% | 557.57 | 1444 / 1445 | 96% | 4.84 | 175 / 183 |
pancreas | 100% | 481.88 | 327 / 328 | 96% | 3.02 | 170 / 178 |
skin | 100% | 721.41 | 1807 / 1809 | 89% | 3.88 | 418 / 472 |
bladder | 100% | 595.19 | 21 / 21 | 86% | 2.63 | 434 / 504 |
stomach | 100% | 572.08 | 358 / 359 | 84% | 2.82 | 241 / 286 |
intestine | 100% | 590.59 | 966 / 966 | 77% | 2.64 | 406 / 527 |
liver | 99% | 324.30 | 223 / 226 | 63% | 1.43 | 257 / 406 |
adipose | 100% | 744.22 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 819.47 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 1.59 | 1 / 1 |
blood vessel | 100% | 563.58 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 99% | 405.75 | 849 / 861 | 0% | 0 | 0 / 0 |
muscle | 98% | 291.99 | 783 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 4.11 | 43 / 45 |
lymph node | 0% | 0 | 0 / 0 | 93% | 2.67 | 27 / 29 |
eye | 0% | 0 | 0 / 0 | 64% | 1.78 | 51 / 80 |
peripheral blood | 44% | 481.36 | 412 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006488 | Biological process | dolichol-linked oligosaccharide biosynthetic process |
GO_0006487 | Biological process | protein N-linked glycosylation |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0098553 | Cellular component | lumenal side of endoplasmic reticulum membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0106073 | Molecular function | dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | ALG10B |
Protein name | dolichyl-P-Glc:Glc2Man9GlcNAc2-PP-dolichol alpha-1,2-glucosyltransferase (EC 2.4.1.256) ALG10 alpha-1,2-glucosyltransferase B Alternative protein ALG10B Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase (EC 2.4.1.256) (Alpha-1,2-glucosyltransferase ALG10-A) (Alpha-2-glucosyltransferase ALG10-B) (Asparagine-linked glycosylation protein 10 homolog B) (Potassium channel regulator 1) |
Synonyms | KCR1 |
Description | FUNCTION: Putative alpha-1,2-glucosyltransferase, which adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol (By similarity). When coupled to KCNH2 may reduce KCNH2 sensitivity to classic proarrhythmic drug blockade, possibly by mediating glycosylation of KCNH2 . Has a role in maintenance of cochlear outer hair cell function (By similarity). . |
Accessions | F8VXJ0 L8E7C9 ENST00000548240.1 Q5I7T1 F8VWA9 ENST00000551464.1 ENST00000308742.9 |