SERP1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	43 studies	59% ± 16%	Explore
macrophage	41 studies	58% ± 20%	Explore
endothelial cell	41 studies	38% ± 15%	Explore
fibroblast	39 studies	42% ± 16%	Explore
natural killer cell	37 studies	46% ± 12%	Explore
CD8-positive, alpha-beta T cell	36 studies	48% ± 17%	Explore
T cell	34 studies	48% ± 14%	Explore
CD4-positive, alpha-beta T cell	32 studies	57% ± 15%	Explore
plasma cell	29 studies	70% ± 21%	Explore
pericyte	29 studies	35% ± 14%	Explore
conventional dendritic cell	29 studies	74% ± 12%	Explore
classical monocyte	28 studies	73% ± 16%	Explore
smooth muscle cell	27 studies	32% ± 11%	Explore
regulatory T cell	26 studies	52% ± 12%	Explore
dendritic cell	25 studies	65% ± 24%	Explore
monocyte	25 studies	61% ± 24%	Explore
plasmacytoid dendritic cell	25 studies	75% ± 14%	Explore
non-classical monocyte	24 studies	82% ± 12%	Explore
basal cell	21 studies	56% ± 18%	Explore
epithelial cell	21 studies	65% ± 20%	Explore
mature NK T cell	20 studies	42% ± 14%	Explore
memory B cell	20 studies	62% ± 10%	Explore
mast cell	19 studies	52% ± 14%	Explore
gamma-delta T cell	19 studies	48% ± 17%	Explore
naive B cell	19 studies	57% ± 12%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	18 studies	54% ± 16%	Explore
ciliated cell	18 studies	62% ± 20%	Explore
endothelial cell of lymphatic vessel	17 studies	37% ± 10%	Explore
connective tissue cell	17 studies	47% ± 15%	Explore
mucosal invariant T cell	16 studies	52% ± 15%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	44% ± 10%	Explore
myeloid cell	15 studies	58% ± 23%	Explore
CD16-negative, CD56-bright natural killer cell, human	14 studies	45% ± 14%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	57% ± 12%	Explore
myofibroblast cell	14 studies	38% ± 11%	Explore
neutrophil	13 studies	46% ± 23%	Explore
endothelial cell of vascular tree	13 studies	40% ± 14%	Explore
plasmablast	12 studies	80% ± 12%	Explore
CD4-positive, alpha-beta memory T cell	12 studies	55% ± 17%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	52% ± 14%	Explore
secretory cell	12 studies	68% ± 21%	Explore
capillary endothelial cell	12 studies	31% ± 13%	Explore
goblet cell	12 studies	49% ± 21%	Explore
vein endothelial cell	12 studies	38% ± 14%	Explore
effector memory CD8-positive, alpha-beta T cell	11 studies	45% ± 17%	Explore
innate lymphoid cell	11 studies	52% ± 17%	Explore
mesothelial cell	11 studies	48% ± 15%	Explore
astrocyte	11 studies	35% ± 12%	Explore
type I pneumocyte	10 studies	39% ± 18%	Explore
type II pneumocyte	10 studies	62% ± 26%	Explore
club cell	10 studies	55% ± 21%	Explore
abnormal cell	10 studies	51% ± 19%	Explore
endothelial cell of artery	10 studies	37% ± 8%	Explore
IgG plasma cell	10 studies	59% ± 24%	Explore
microglial cell	10 studies	34% ± 19%	Explore
platelet	9 studies	37% ± 13%	Explore
leukocyte	9 studies	59% ± 17%	Explore
T follicular helper cell	9 studies	52% ± 15%	Explore
alveolar macrophage	8 studies	52% ± 25%	Explore
progenitor cell	8 studies	65% ± 12%	Explore
IgA plasma cell	8 studies	69% ± 22%	Explore
hematopoietic stem cell	8 studies	68% ± 17%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	49% ± 8%	Explore
mononuclear phagocyte	7 studies	56% ± 27%	Explore
oligodendrocyte precursor cell	7 studies	36% ± 10%	Explore
hematopoietic precursor cell	6 studies	64% ± 24%	Explore
ionocyte	6 studies	41% ± 14%	Explore
respiratory goblet cell	6 studies	55% ± 20%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	61% ± 11%	Explore
epithelial cell of proximal tubule	6 studies	29% ± 8%	Explore
kidney loop of Henle epithelial cell	6 studies	36% ± 7%	Explore
renal alpha-intercalated cell	6 studies	49% ± 8%	Explore
neuron	6 studies	34% ± 14%	Explore
enterocyte	6 studies	40% ± 13%	Explore
precursor B cell	6 studies	61% ± 9%	Explore
adipocyte	6 studies	22% ± 5%	Explore
erythrocyte	6 studies	45% ± 22%	Explore
intermediate monocyte	6 studies	72% ± 29%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	65% ± 11%	Explore
oligodendrocyte	6 studies	28% ± 8%	Explore
CD4-positive helper T cell	5 studies	49% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	35% ± 11%	Explore
exhausted T cell	5 studies	53% ± 8%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	47% ± 4%	Explore
enteroendocrine cell	5 studies	49% ± 19%	Explore
intestinal crypt stem cell	5 studies	46% ± 21%	Explore
transit amplifying cell	5 studies	47% ± 17%	Explore
glutamatergic neuron	5 studies	52% ± 20%	Explore
erythroblast	5 studies	46% ± 21%	Explore
pro-B cell	5 studies	56% ± 21%	Explore
T-helper 17 cell	5 studies	63% ± 14%	Explore
group 3 innate lymphoid cell	5 studies	74% ± 7%	Explore
immature B cell	5 studies	67% ± 8%	Explore
mucus secreting cell	5 studies	59% ± 23%	Explore
granulocyte	5 studies	59% ± 10%	Explore
GABAergic neuron	5 studies	45% ± 13%	Explore
interneuron	5 studies	37% ± 19%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	45% ± 11%	Explore
deuterosomal cell	4 studies	47% ± 12%	Explore
duct epithelial cell	4 studies	60% ± 19%	Explore
pancreatic A cell	4 studies	59% ± 19%	Explore
type B pancreatic cell	4 studies	68% ± 20%	Explore
retinal bipolar neuron	4 studies	29% ± 11%	Explore
lymphocyte	4 studies	49% ± 20%	Explore
adventitial cell	4 studies	40% ± 7%	Explore
cardiac muscle cell	4 studies	24% ± 4%	Explore
Mueller cell	4 studies	34% ± 11%	Explore
acinar cell	4 studies	63% ± 28%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	81% ± 5%	Explore
luminal cell of prostate epithelium	4 studies	65% ± 21%	Explore
IgM plasma cell	4 studies	62% ± 26%	Explore
hepatocyte	4 studies	54% ± 23%	Explore
T-helper 1 cell	4 studies	68% ± 8%	Explore
double negative thymocyte	4 studies	57% ± 19%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	44% ± 20%	Explore
hillock cell	3 studies	34% ± 13%	Explore
squamous epithelial cell	3 studies	58% ± 19%	Explore
pancreatic D cell	3 studies	62% ± 21%	Explore
monocyte-derived dendritic cell	3 studies	79% ± 13%	Explore
glomerular endothelial cell	3 studies	21% ± 4%	Explore
neural crest cell	3 studies	39% ± 4%	Explore
renal principal cell	3 studies	49% ± 8%	Explore
thymocyte	3 studies	58% ± 24%	Explore
extravillous trophoblast	3 studies	79% ± 12%	Explore
placental villous trophoblast	3 studies	69% ± 16%	Explore
megakaryocyte	3 studies	57% ± 6%	Explore
brush cell	3 studies	37% ± 25%	Explore
neuroendocrine cell	3 studies	58% ± 17%	Explore
amacrine cell	3 studies	37% ± 6%	Explore
retinal pigment epithelial cell	3 studies	39% ± 18%	Explore
serous secreting cell	3 studies	80% ± 13%	Explore
tissue-resident macrophage	3 studies	50% ± 22%	Explore
intraepithelial lymphocyte	3 studies	45% ± 18%	Explore
rod bipolar cell	3 studies	21% ± 4%	Explore
germinal center B cell	3 studies	69% ± 4%	Explore
myoepithelial cell	3 studies	46% ± 6%	Explore
inflammatory macrophage	3 studies	54% ± 15%	Explore
muscle cell	3 studies	39% ± 14%	Explore
pancreatic ductal cell	3 studies	56% ± 15%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	77% ± 15%	Explore
glial cell	3 studies	43% ± 18%	Explore
melanocyte	3 studies	26% ± 7%	Explore
keratinocyte	3 studies	51% ± 18%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	60% ± 9%	Explore
double-positive, alpha-beta thymocyte	3 studies	66% ± 11%	Explore
progenitor cell of mammary luminal epithelium	3 studies	73% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	20 studies	58% ± 15%	Explore
lung	19 studies	53% ± 16%	Explore
intestine	12 studies	45% ± 19%	Explore
brain	12 studies	37% ± 16%	Explore
kidney	8 studies	43% ± 14%	Explore
eye	7 studies	31% ± 13%	Explore
bone marrow	7 studies	36% ± 17%	Explore
liver	7 studies	45% ± 20%	Explore
lymph node	6 studies	58% ± 18%	Explore
pancreas	5 studies	57% ± 24%	Explore
uterus	5 studies	52% ± 20%	Explore
prostate	5 studies	52% ± 25%	Explore
placenta	4 studies	55% ± 20%	Explore
heart	4 studies	22% ± 5%	Explore
adipose	4 studies	27% ± 13%	Explore
breast	4 studies	61% ± 5%	Explore
adrenal gland	3 studies	44% ± 15%	Explore
esophagus	3 studies	53% ± 24%	Explore
thymus	3 studies	60% ± 30%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	9989.57	578 / 578	100%	148.66	1155 / 1155
ovary	100%	8910.32	180 / 180	100%	159.47	430 / 430
pancreas	100%	17729.12	328 / 328	100%	95.70	178 / 178
prostate	100%	10198.98	245 / 245	100%	275.65	502 / 502
stomach	100%	9978.30	359 / 359	100%	118.40	286 / 286
esophagus	100%	6398.47	1444 / 1445	100%	131.03	183 / 183
brain	100%	5760.44	2639 / 2642	100%	93.34	705 / 705
thymus	100%	8522.02	653 / 653	100%	119.89	604 / 605
breast	100%	7953.63	459 / 459	100%	171.66	1116 / 1118
intestine	100%	6358.75	966 / 966	100%	123.63	526 / 527
bladder	100%	6628.24	21 / 21	100%	111.34	503 / 504
uterus	100%	6112.35	170 / 170	100%	131.59	458 / 459
liver	100%	10552.11	226 / 226	100%	83.36	404 / 406
adrenal gland	100%	11130.69	258 / 258	97%	64.55	224 / 230
kidney	100%	7030.88	89 / 89	97%	72.50	877 / 901
skin	100%	7029.87	1808 / 1809	97%	72.54	459 / 472
adipose	100%	7443.98	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	122.93	29 / 29
spleen	100%	9182.71	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	123.54	45 / 45
ureter	0%	0	0 / 0	100%	53.61	1 / 1
blood vessel	100%	6946.72	1332 / 1335	0%	0	0 / 0
peripheral blood	99%	9161.93	920 / 929	0%	0	0 / 0
heart	88%	2573.21	761 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	74%	28.65	59 / 80
muscle	39%	689.65	315 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0060124	Biological process	positive regulation of growth hormone secretion
GO_0009791	Biological process	post-embryonic development
GO_0032024	Biological process	positive regulation of insulin secretion
GO_0030968	Biological process	endoplasmic reticulum unfolded protein response
GO_0036211	Biological process	protein modification process
GO_0007009	Biological process	plasma membrane organization
GO_0048644	Biological process	muscle organ morphogenesis
GO_0045727	Biological process	positive regulation of translation
GO_0030073	Biological process	insulin secretion
GO_0001501	Biological process	skeletal system development
GO_0046622	Biological process	positive regulation of organ growth
GO_0006006	Biological process	glucose metabolic process
GO_0006486	Biological process	protein glycosylation
GO_0005840	Cellular component	ribosome
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0005783	Cellular component	endoplasmic reticulum
GO_0005829	Cellular component	cytosol
GO_0005881	Cellular component	cytoplasmic microtubule
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	SERP1
Protein name	Stress-associated endoplasmic reticulum protein 1 (Ribosome-attached membrane protein 4) Stress-associated endoplasmic reticulum protein
Synonyms	RAMP4
Description	FUNCTION: Interacts with target proteins during their translocation into the lumen of the endoplasmic reticulum. Protects unfolded target proteins against degradation during ER stress. May facilitate glycosylation of target proteins after termination of ER stress. May modulate the use of N-glycosylation sites on target proteins. . FUNCTION: Interacts with target proteins during their translocation into the lumen of the endoplasmic reticulum. Protects unfolded target proteins against degradation during ER stress. May facilitate glycosylation of target proteins after termination of ER stress. May modulate the use of N-glycosylation sites on target proteins. .; FUNCTION: Interacts with target proteins during translocation into the lumen of the endoplasmic reticulum. Protects unfolded target proteins against degradation and facilitate correct glycosylation. . FUNCTION: Interacts with target proteins during their translocation into the lumen of the endoplasmic reticulum. Protects unfolded target proteins against degradation during ER stress. May facilitate glycosylation of target proteins after termination of ER stress. May modulate the use of N-glycosylation sites on target proteins. .; FUNCTION: Interacts with target proteins during translocation into the lumen of the endoplasmic reticulum. Protects unfolded target proteins against degradation and facilitate correct glycosylation. .
Accessions	C9JSB0 ENST00000491660.1 ENST00000487153.1 ENST00000239944.7 ENST00000479209.1 Q9Y6X1 C9JUH5

SERP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review