MSRB3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030091Biological processprotein repair
GO_0006979Biological processresponse to oxidative stress
GO_0005783Cellular componentendoplasmic reticulum
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005739Cellular componentmitochondrion
GO_0033743Molecular functionpeptide-methionine (R)-S-oxide reductase activity
GO_0005515Molecular functionprotein binding
GO_0033745Molecular functionL-methionine-(R)-S-oxide reductase activity
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameMSRB3
Protein nameMethionine sulfoxide reductase B3
Methionine-R-sulfoxide reductase B3 (MsrB3) (EC 1.8.4.12) (EC 1.8.4.14)
Peptide-methionine (R)-S-oxide reductase (EC 1.8.4.12)
SynonymsUNQ1965/PRO4487
DescriptionFUNCTION: Catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine. Isoform 2 is essential for hearing. .

FUNCTION: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues. .

FUNCTION: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues. .

FUNCTION: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues. .

FUNCTION: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues. .

AccessionsENST00000540804.5
ENST00000642411.1 [Q8IXL7-2]
F5H199
ENST00000541897.5
H7C2B7
F5H4C9
ENST00000535664.5 [Q8IXL7-2]
ENST00000535239.5
ENST00000614640.4 [Q8IXL7-2]
ENST00000355192.8 [Q8IXL7-1]
ENST00000642404.1 [Q8IXL7-2]
F5H7C4
Q8IXL7
F5H6G9
ENST00000541189.5
ENST00000647481.1
ENST00000308259.10 [Q8IXL7-2]
A0A2R8Y7J8
ENST00000646299.1 [Q8IXL7-2]
ENST00000538045.5
ENST00000446731.2
H0YFW5