AGPAT4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006654Biological processphosphatidic acid biosynthetic process
GO_0008654Biological processphospholipid biosynthetic process
GO_0016024Biological processCDP-diacylglycerol biosynthetic process
GO_0005741Cellular componentmitochondrial outer membrane
GO_0005783Cellular componentendoplasmic reticulum
GO_0012505Cellular componentendomembrane system
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0003841Molecular function1-acylglycerol-3-phosphate O-acyltransferase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameAGPAT4
Protein nameAGPAT4 protein
1-acyl-sn-glycerol-3-phosphate acyltransferase delta (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 4) (1-AGP acyltransferase 4) (1-AGPAT 4) (Lysophosphatidic acid acyltransferase delta) (LPAAT-delta)
1-acylglycerol-3-phosphate O-acyltransferase (EC 2.3.1.51)
1-acylglycerol-3-phosphate O-acyltransferase 4
SynonymsUNQ499/PRO1016
hCG_1781301
DKFZp686G10113
DescriptionFUNCTION: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity). Exhibits high acyl-CoA specificity for polyunsaturated fatty acyl-CoA, especially docosahexaenoyl-CoA (22:6-CoA, DHA-CoA) (By similarity). .

AccessionsENST00000366911.9
Q9NRZ5
ENST00000437165.1
Q6PJN9
Q6AI25
ENST00000436279.1
B4DHC0
ENST00000320285.9 [Q9NRZ5-1]
ENST00000366905.3
G3XAF1
Q5TEE8
H0Y5R3