Name | Number of supported studies | Average coverage | |
---|---|---|---|
retinal ganglion cell | 4 studies | 51% ± 23% | |
endothelial cell of lymphatic vessel | 4 studies | 22% ± 6% | |
glutamatergic neuron | 3 studies | 35% ± 15% |
Insufficient scRNA-seq data for expression of KCTD17 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 4387.21 | 2640 / 2642 | 100% | 57.54 | 705 / 705 |
bladder | 100% | 1334.95 | 21 / 21 | 97% | 24.01 | 488 / 504 |
intestine | 98% | 1118.82 | 949 / 966 | 98% | 24.94 | 514 / 527 |
adrenal gland | 100% | 1127.11 | 257 / 258 | 96% | 39.57 | 220 / 230 |
lung | 96% | 751.18 | 555 / 578 | 95% | 19.05 | 1099 / 1155 |
ovary | 100% | 1029.48 | 180 / 180 | 91% | 14.15 | 391 / 430 |
uterus | 99% | 1232.90 | 168 / 170 | 89% | 19.84 | 407 / 459 |
skin | 100% | 1442.08 | 1805 / 1809 | 87% | 20.48 | 409 / 472 |
thymus | 94% | 634.38 | 612 / 653 | 90% | 18.47 | 547 / 605 |
breast | 85% | 518.36 | 389 / 459 | 94% | 15.47 | 1055 / 1118 |
esophagus | 87% | 866.17 | 1259 / 1445 | 89% | 15.02 | 163 / 183 |
prostate | 98% | 927.50 | 240 / 245 | 74% | 7.57 | 373 / 502 |
stomach | 55% | 455.93 | 196 / 359 | 94% | 23.92 | 268 / 286 |
kidney | 51% | 295.62 | 45 / 89 | 80% | 12.55 | 723 / 901 |
pancreas | 9% | 37.74 | 28 / 328 | 97% | 23.62 | 172 / 178 |
lymph node | 0% | 0 | 0 / 0 | 100% | 35.29 | 29 / 29 |
ureter | 0% | 0 | 0 / 0 | 100% | 5.75 | 1 / 1 |
spleen | 100% | 868.07 | 240 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 963.04 | 1317 / 1335 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 15.16 | 43 / 45 |
heart | 87% | 1043.52 | 752 / 861 | 0% | 0 | 0 / 0 |
adipose | 86% | 550.49 | 1037 / 1204 | 0% | 0 | 0 / 0 |
liver | 11% | 54.62 | 24 / 226 | 62% | 16.05 | 250 / 406 |
peripheral blood | 58% | 340.16 | 541 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 57% | 7.55 | 46 / 80 |
muscle | 1% | 3.90 | 8 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0051260 | Biological process | protein homooligomerization |
GO_0045724 | Biological process | positive regulation of cilium assembly |
GO_0030030 | Biological process | cell projection organization |
GO_0032469 | Biological process | endoplasmic reticulum calcium ion homeostasis |
GO_0043161 | Biological process | proteasome-mediated ubiquitin-dependent protein catabolic process |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0031463 | Cellular component | Cul3-RING ubiquitin ligase complex |
GO_0005737 | Cellular component | cytoplasm |
GO_1990756 | Molecular function | ubiquitin-like ligase-substrate adaptor activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0097602 | Molecular function | cullin family protein binding |
GO_0005515 | Molecular function | protein binding |
Gene name | KCTD17 |
Protein name | Potassium channel tetramerization domain containing 17 BTB/POZ domain-containing protein KCTD17 |
Synonyms | |
Description | FUNCTION: Substrate-adapter for CUL3-RING ubiquitin ligase complexes which mediates the ubiquitination and subsequent proteasomal degradation of TCHP, a protein involved in ciliogenesis down-regulation. Thereby, positively regulates ciliogenesis, playing a crucial role in the initial steps of axoneme extension . May also play a role in endoplasmic reticulum calcium ion homeostasis . . |
Accessions | A0A087WX35 ENST00000456470.1 Q8N5Z5 ENST00000402077.8 [Q8N5Z5-2] B0QYB2 H0Y731 H7C323 ENST00000431531.1 ENST00000403888.8 [Q8N5Z5-1] ENST00000421900.5 ENST00000610767.5 |